Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "[:1:22-1:33:writable] Warning: Modelica only supports 32-bit signed integers! Transforming: 13743895347 into a real [:1:1-1:33:writable] Error: Class GC_set_max_heap_size not found in scope (looking for a function or record). Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.0003278/0.0003278, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.0003811/0.0003811, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 0.3303/0.3303, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Drugs/ATC/B/B02BD15.mo:9:22-9:32:writable] Warning: Modelica only supports 32-bit signed integers! Transforming: 6000000000 into a real [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 0.8637/0.8637, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 179] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: simulate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment,startTime=0,stopTime=864000,tolerance=1e-06,numberOfIntervals=86400,outputFormat="empty",variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment",simflags="-abortSlowSimulation -alarm=240 -lv LOG_STATS") simulate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment,startTime=0,stopTime=864000,tolerance=1e-06,numberOfIntervals=86400,outputFormat="empty",variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment",simflags="-abortSlowSimulation -alarm=240 -lv LOG_STATS") [Timeout 900] "Notification: Performance of FrontEnd - loaded program: time 7.51e-07/7.51e-07, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FrontEnd - Absyn->SCode: time 2.533e-05/2.608e-05, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment): time 0.02018/0.02021, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFInst.instExpressions: time 0.00902/0.02923, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFInst.updateImplicitVariability: time 0.001175/0.03041, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFTyping.typeComponents: time 0.001565/0.03197, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFTyping.typeBindings: time 0.003257/0.03523, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFTyping.typeClassSections: time 0.002946/0.03817, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFFlatten.flatten: time 0.003015/0.04119, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFFlatten.resolveConnections: time 0.001175/0.04236, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFEvalConstants.evaluate: time 0.002465/0.04483, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFSimplifyModel.simplify: time 0.001273/0.0461, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFPackage.collectConstants: time 0.0005118/0.04661, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFFlatten.collectFunctions: time 0.0008741/0.04749, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFScalarize.scalarize: time 0.0004957/0.04798, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFVerifyModel.verify: time 0.001099/0.04908, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFConvertDAE.convert: time 0.004629/0.05371, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FrontEnd - DAE generated: time 0.0002357/0.05395, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FrontEnd: time 2.645e-06/0.05395, allocations: 0 / 0, free: 0 / 0 Notification: Performance of Transformations before backend: time 2.844e-05/0.05398, allocations: 0 / 0, free: 0 / 0 Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 233 * Number of variables: 233 Notification: Performance of Generate backend data structure: time 0.007311/0.06129, allocations: 0 / 0, free: 0 / 0 Notification: Performance of prepare preOptimizeDAE: time 0.0001628/0.06145, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt normalInlineFunction (simulation): time 0.003394/0.06485, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt evaluateParameters (simulation): time 0.003745/0.06859, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt simplifyIfEquations (simulation): time 0.0002352/0.06883, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt expandDerOperator (simulation): time 0.0005652/0.06939, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt clockPartitioning (simulation): time 0.005571/0.07496, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt findStateOrder (simulation): time 0.0001658/0.07513, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt replaceEdgeChange (simulation): time 0.0003663/0.07549, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt inlineArrayEqn (simulation): time 4.145e-05/0.07554, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt removeEqualRHS (simulation): time 0.003881/0.07942, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.01104/0.09046, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt comSubExp (simulation): time 0.003527/0.09398, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt resolveLoops (simulation): time 0.001845/0.09583, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt evalFunc (simulation): time 8.075e-05/0.09591, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.003314/0.09922, allocations: 0 / 0, free: 0 / 0 Notification: Performance of pre-optimization done (n=157): time 2.016e-05/0.09924, allocations: 0 / 0, free: 0 / 0 Notification: Performance of matching and sorting (n=165): time 0.02251/0.1217, allocations: 0 / 0, free: 0 / 0 Notification: Performance of inlineWhenForInitialization (initialization): time 0.0002403/0.122, allocations: 0 / 0, free: 0 / 0 Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.004039/0.126, allocations: 0 / 0, free: 0 / 0 Notification: Performance of collectPreVariables (initialization): time 0.0004262/0.1265, allocations: 0 / 0, free: 0 / 0 Notification: Performance of collectInitialEqns (initialization): time 0.001299/0.1278, allocations: 0 / 0, free: 0 / 0 Notification: Performance of collectInitialBindings (initialization): time 0.0009607/0.1287, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simplifyInitialFunctions (initialization): time 0.00143/0.1301, allocations: 0 / 0, free: 0 / 0 Notification: Performance of setup shared object (initialization): time 0.0001588/0.1303, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preBalanceInitialSystem (initialization): time 0.002382/0.1327, allocations: 0 / 0, free: 0 / 0 Notification: Performance of partitionIndependentBlocks (initialization): time 0.003074/0.1358, allocations: 0 / 0, free: 0 / 0 Notification: Performance of analyzeInitialSystem (initialization): time 0.006758/0.1425, allocations: 0 / 0, free: 0 / 0 Notification: Performance of solveInitialSystemEqSystem (initialization): time 3.764e-05/0.1426, allocations: 0 / 0, free: 0 / 0 Notification: Performance of matching and sorting (n=229) (initialization): time 0.008765/0.1513, allocations: 0 / 0, free: 0 / 0 Notification: Performance of prepare postOptimizeDAE: time 0.0002456/0.1516, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyComplexFunction (initialization): time 3.994e-05/0.1516, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt tearingSystem (initialization): time 6.109e-05/0.1517, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.002204/0.1539, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 5.334e-05/0.1539, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.001535/0.1555, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.0005154/0.156, allocations: 0 / 0, free: 0 / 0 Warning: Assuming fixed start value for the following 40 variables: patient4.dose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient4.dose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient4.dose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient4.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_citalopram_CYP2C19_2.dose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_citalopram_CYP2C19_2.dose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_citalopram_CYP2C19_2.dose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_citalopram_CYP2C19_2.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient2.dose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient2.dose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient2.dose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient2.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_citalopram_normal.dose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_citalopram_normal.dose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_citalopram_normal.dose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_citalopram_normal.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_citalopram_normal.dose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_citalopram_normal.dose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_citalopram_normal.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_citalopram_normal.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient2.dose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient2.dose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient2.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient2.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_citalopram_CYP2C19_2.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_citalopram_CYP2C19_2.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient4.dose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient4.dose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient4.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient4.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_citalopram_normal.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_citalopram_normal.dose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient2.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient2.dose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_citalopram_CYP2C19_2.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_citalopram_CYP2C19_2.dose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient4.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient4.dose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 41 * Number of states: 0 () * Number of discrete variables: 92 ($PRE.patient_citalopram_normal.dose.absorptionLumen.Cmin,patient_citalopram_normal.dose.absorptionLumen.Cmin,$PRE.patient_citalopram_normal.dose.absorptionLumen.Cmax,patient_citalopram_normal.dose.absorptionLumen.Cmax,$PRE.patient_citalopram_normal.central.Cmin,patient_citalopram_normal.central.Cmin,$PRE.patient_citalopram_normal.central.Cmax,patient_citalopram_normal.central.Cmax,$PRE.patient2.dose.absorptionLumen.Cmin,patient2.dose.absorptionLumen.Cmin,$PRE.patient2.dose.absorptionLumen.Cmax,patient2.dose.absorptionLumen.Cmax,$PRE.patient2.central.Cmin,patient2.central.Cmin,$PRE.patient2.central.Cmax,patient2.central.Cmax,$PRE.patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmin,patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmin,$PRE.patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmax,patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmax,$PRE.patient_citalopram_CYP2C19_2.central.Cmin,patient_citalopram_CYP2C19_2.central.Cmin,$PRE.patient_citalopram_CYP2C19_2.central.Cmax,patient_citalopram_CYP2C19_2.central.Cmax,$PRE.patient4.dose.absorptionLumen.Cmin,patient4.dose.absorptionLumen.Cmin,$PRE.patient4.dose.absorptionLumen.Cmax,patient4.dose.absorptionLumen.Cmax,$PRE.patient4.central.Cmin,patient4.central.Cmin,$PRE.patient4.central.Cmax,patient4.central.Cmax,$PRE.patient_citalopram_normal.central.rising,$PRE.patient_citalopram_normal.dose.pulse.count,$PRE.patient_citalopram_normal.dose.pulse.T_start,$PRE.patient_citalopram_normal.dose.absorptionLumen.rising,patient_citalopram_normal.CYP2C19.status,patient_citalopram_normal.SLC22A2.status,patient_citalopram_normal.central.rising,patient_citalopram_normal.dose.pulse.count,patient_citalopram_normal.dose.pulse.T_start,patient_citalopram_normal.dose.absorptionLumen.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$PRE.patient2.central.rising,$PRE.patient2.dose.pulse.count,$PRE.patient2.dose.pulse.T_start,$PRE.patient2.dose.absorptionLumen.rising,patient2.CYP2C19.status,patient2.SLC22A2.status,patient2.central.rising,patient2.dose.pulse.count,patient2.dose.pulse.T_start,patient2.dose.absorptionLumen.rising,$whenCondition15,$whenCondition14,$whenCondition13,$whenCondition12,$whenCondition11,$PRE.patient_citalopram_CYP2C19_2.central.rising,$PRE.patient_citalopram_CYP2C19_2.dose.pulse.count,$PRE.patient_citalopram_CYP2C19_2.dose.pulse.T_start,$PRE.patient_citalopram_CYP2C19_2.dose.absorptionLumen.rising,patient_citalopram_CYP2C19_2.CYP2C19.status,patient_citalopram_CYP2C19_2.SLC22A2.status,patient_citalopram_CYP2C19_2.central.rising,patient_citalopram_CYP2C19_2.dose.pulse.count,patient_citalopram_CYP2C19_2.dose.pulse.T_start,patient_citalopram_CYP2C19_2.dose.absorptionLumen.rising,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition7,$whenCondition6,$PRE.patient4.central.rising,$PRE.patient4.dose.pulse.count,$PRE.patient4.dose.pulse.T_start,$PRE.patient4.dose.absorptionLumen.rising,patient4.CYP2C19.status,patient4.SLC22A2.status,patient4.central.rising,patient4.dose.pulse.count,patient4.dose.pulse.T_start,patient4.dose.absorptionLumen.rising,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (209): * Single equations (assignments): 189 * Array equations: 0 * Algorithm blocks: 20 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.002336/0.1583, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt lateInlineFunction (simulation): time 0.001811/0.1601, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.0006883/0.1608, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt inlineArrayEqn (simulation): time 2.197e-05/0.1608, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt constantLinearSystem (simulation): time 1.966e-05/0.1609, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifysemiLinear (simulation): time 2.687e-05/0.1609, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.01448/0.1754, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyComplexFunction (simulation): time 1.947e-05/0.1754, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.001729/0.1771, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt tearingSystem (simulation): time 2.353e-05/0.1771, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0003804/0.1775, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 2.189e-05/0.1775, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 6.001e-06/0.1775, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt symbolicJacobian (simulation): time 0.01107/0.1886, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt removeConstants (simulation): time 0.002489/0.1911, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0008866/0.192, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.001477/0.1935, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt findZeroCrossings (simulation): time 0.001305/0.1948, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt collapseArrayExpressions (simulation): time 0.0004732/0.1952, allocations: 0 / 0, free: 0 / 0 Notification: Performance of sorting global known variables: time 0.0021/0.1973, allocations: 0 / 0, free: 0 / 0 Notification: Performance of sort global known variables: time 4.028e-05/0.1974, allocations: 0 / 0, free: 0 / 0 Notification: Performance of remove unused functions: time 0.003992/0.2014, allocations: 0 / 0, free: 0 / 0 Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 5 * Number of states: 28 (patient4.dose.TotalCumulativeMass,patient4.dose.absorptionLumen.C,patient4.dose.absorptionLumen.AUC,patient4.dose.variableDose.TotalCumulativeMass,patient4.central.C,patient4.central.AUC,patient4.elim.MExc,patient_citalopram_CYP2C19_2.dose.TotalCumulativeMass,patient_citalopram_CYP2C19_2.dose.absorptionLumen.C,patient_citalopram_CYP2C19_2.dose.absorptionLumen.AUC,patient_citalopram_CYP2C19_2.dose.variableDose.TotalCumulativeMass,patient_citalopram_CYP2C19_2.central.C,patient_citalopram_CYP2C19_2.central.AUC,patient_citalopram_CYP2C19_2.elim.MExc,patient2.dose.TotalCumulativeMass,patient2.dose.absorptionLumen.C,patient2.dose.absorptionLumen.AUC,patient2.dose.variableDose.TotalCumulativeMass,patient2.central.C,patient2.central.AUC,patient2.elim.MExc,patient_citalopram_normal.dose.TotalCumulativeMass,patient_citalopram_normal.dose.absorptionLumen.C,patient_citalopram_normal.dose.absorptionLumen.AUC,patient_citalopram_normal.dose.variableDose.TotalCumulativeMass,patient_citalopram_normal.central.C,patient_citalopram_normal.central.AUC,patient_citalopram_normal.elim.MExc) * Number of discrete variables: 60 ($whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,patient4.dose.absorptionLumen.Cmax,patient4.dose.absorptionLumen.Cmin,patient4.dose.absorptionLumen.rising,patient4.dose.pulse.T_start,patient4.dose.pulse.count,patient4.central.Cmax,patient4.central.Cmin,patient4.central.rising,patient4.SLC22A2.status,patient4.CYP2C19.status,$whenCondition6,$whenCondition7,$whenCondition8,$whenCondition9,$whenCondition10,patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmax,patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmin,patient_citalopram_CYP2C19_2.dose.absorptionLumen.rising,patient_citalopram_CYP2C19_2.dose.pulse.T_start,patient_citalopram_CYP2C19_2.dose.pulse.count,patient_citalopram_CYP2C19_2.central.Cmax,patient_citalopram_CYP2C19_2.central.Cmin,patient_citalopram_CYP2C19_2.central.rising,patient_citalopram_CYP2C19_2.SLC22A2.status,patient_citalopram_CYP2C19_2.CYP2C19.status,$whenCondition11,$whenCondition12,$whenCondition13,$whenCondition14,$whenCondition15,patient2.dose.absorptionLumen.Cmax,patient2.dose.absorptionLumen.Cmin,patient2.dose.absorptionLumen.rising,patient2.dose.pulse.T_start,patient2.dose.pulse.count,patient2.central.Cmax,patient2.central.Cmin,patient2.central.rising,patient2.SLC22A2.status,patient2.CYP2C19.status,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,patient_citalopram_normal.dose.absorptionLumen.Cmax,patient_citalopram_normal.dose.absorptionLumen.Cmin,patient_citalopram_normal.dose.absorptionLumen.rising,patient_citalopram_normal.dose.pulse.T_start,patient_citalopram_normal.dose.pulse.count,patient_citalopram_normal.central.Cmax,patient_citalopram_normal.central.Cmin,patient_citalopram_normal.central.rising,patient_citalopram_normal.SLC22A2.status,patient_citalopram_normal.CYP2C19.status) * Number of discrete states: 52 (patient_citalopram_normal.dose.pulse.count,patient_citalopram_normal.SLC22A2.status,patient_citalopram_normal.CYP2C19.status,patient_citalopram_normal.dose.absorptionLumen.Cmin,$whenCondition20,patient_citalopram_normal.dose.absorptionLumen.Cmax,$whenCondition19,patient_citalopram_normal.dose.absorptionLumen.rising,patient_citalopram_normal.central.Cmin,$whenCondition18,patient_citalopram_normal.central.Cmax,$whenCondition17,patient_citalopram_normal.central.rising,patient2.dose.pulse.count,patient2.SLC22A2.status,patient2.CYP2C19.status,patient2.dose.absorptionLumen.Cmin,$whenCondition15,patient2.dose.absorptionLumen.Cmax,$whenCondition14,patient2.dose.absorptionLumen.rising,patient2.central.Cmin,$whenCondition13,patient2.central.Cmax,$whenCondition12,patient2.central.rising,patient_citalopram_CYP2C19_2.dose.pulse.count,patient_citalopram_CYP2C19_2.SLC22A2.status,patient_citalopram_CYP2C19_2.CYP2C19.status,patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmin,$whenCondition10,patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmax,$whenCondition9,patient_citalopram_CYP2C19_2.dose.absorptionLumen.rising,patient_citalopram_CYP2C19_2.central.Cmin,$whenCondition8,patient_citalopram_CYP2C19_2.central.Cmax,$whenCondition7,patient_citalopram_CYP2C19_2.central.rising,patient4.dose.pulse.count,patient4.SLC22A2.status,patient4.CYP2C19.status,patient4.dose.absorptionLumen.Cmin,$whenCondition5,patient4.dose.absorptionLumen.Cmax,$whenCondition4,patient4.dose.absorptionLumen.rising,patient4.central.Cmin,$whenCondition3,patient4.central.Cmax,$whenCondition2,patient4.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (133): * Single equations (assignments): 109 * Array equations: 0 * Algorithm blocks: 16 * Record equations: 0 * When equations: 8 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.001243/0.2026, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created initialization part: time 0.005993/0.2086, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created event and clocks part: time 4.017e-06/0.2086, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created simulation system equations: time 0.0031/0.2117, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.006247/0.218, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.01306/0.231, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: some other stuff during SimCode phase: time 0.001281/0.2323, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: alias equations: time 0.001258/0.2336, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: all other stuff during SimCode phase: time 0.0009668/0.2345, allocations: 0 / 0, free: 0 / 0 Notification: Performance of SimCode: time 5.086e-05/0.2346, allocations: 0 / 0, free: 0 / 0 Notification: Performance of Templates: time 0.004618/0.2392, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 899] [Calling sys.exit(0), Time elapsed: 3.322147054132074]