Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.002321/0.002321, allocations: 80.44 kB / 19.17 MB, free: 0.7422 MB / 13.93 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.002989/0.002989, allocations: 165.9 kB / 22.45 MB, free: 2.105 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 1.636/1.636, allocations: 177.1 MB / 202.8 MB, free: 5.512 MB / 186.7 MB " [Timeout remaining time 178] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 3.463/3.463, allocations: 274 MB / 0.5207 GB, free: 14.91 MB / 458.7 MB " [Timeout remaining time 176] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") [Timeout 660] "Notification: Performance of FrontEnd - loaded program: time 2.775e-06/2.775e-06, allocations: 0 / 0.7563 GB, free: 9.906 MB / 0.5887 GB Notification: Performance of FrontEnd - Absyn->SCode: time 3.18e-05/3.458e-05, allocations: 7.828 kB / 0.7563 GB, free: 9.898 MB / 0.5887 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic): time 0.02546/0.0255, allocations: 11.69 MB / 0.7677 GB, free: 14.23 MB / 0.6043 GB Notification: Performance of NFInst.instExpressions: time 0.009709/0.03521, allocations: 2.67 MB / 0.7703 GB, free: 11.56 MB / 0.6043 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.001521/0.03673, allocations: 23.94 kB / 0.7703 GB, free: 11.54 MB / 0.6043 GB Notification: Performance of NFTyping.typeComponents: time 0.000804/0.03753, allocations: 304.9 kB / 0.7706 GB, free: 11.24 MB / 0.6043 GB Notification: Performance of NFTyping.typeBindings: time 0.002232/0.03976, allocations: 0.9102 MB / 0.7715 GB, free: 10.32 MB / 0.6043 GB Notification: Performance of NFTyping.typeClassSections: time 0.00172/0.04148, allocations: 0.6787 MB / 0.7722 GB, free: 9.641 MB / 0.6043 GB Notification: Performance of NFFlatten.flatten: time 0.0044/0.04588, allocations: 3.265 MB / 0.7754 GB, free: 6.359 MB / 0.6043 GB Notification: Performance of NFFlatten.resolveConnections: time 0.0009468/0.04683, allocations: 454.7 kB / 0.7758 GB, free: 5.887 MB / 0.6043 GB Notification: Performance of NFEvalConstants.evaluate: time 0.002395/0.04922, allocations: 1.645 MB / 0.7774 GB, free: 4.238 MB / 0.6043 GB Notification: Performance of NFSimplifyModel.simplify: time 0.001628/0.05085, allocations: 0.9113 MB / 0.7783 GB, free: 3.324 MB / 0.6043 GB Notification: Performance of NFPackage.collectConstants: time 0.0004522/0.05131, allocations: 280 kB / 0.7786 GB, free: 3.051 MB / 0.6043 GB Notification: Performance of NFFlatten.collectFunctions: time 0.0005045/0.05181, allocations: 288 kB / 0.7788 GB, free: 2.77 MB / 0.6043 GB Notification: Performance of NFScalarize.scalarize: time 0.0005106/0.05232, allocations: 0.5019 MB / 0.7793 GB, free: 2.266 MB / 0.6043 GB Notification: Performance of NFVerifyModel.verify: time 0.001331/0.05365, allocations: 0.9554 MB / 0.7803 GB, free: 1.309 MB / 0.6043 GB Notification: Performance of NFConvertDAE.convert: time 0.003818/0.05747, allocations: 3.082 MB / 0.7833 GB, free: 14.21 MB / 0.6199 GB Notification: Performance of FrontEnd - DAE generated: time 7.444e-06/0.05748, allocations: 4 kB / 0.7833 GB, free: 14.21 MB / 0.6199 GB Notification: Performance of FrontEnd: time 1.473e-06/0.05748, allocations: 4 kB / 0.7833 GB, free: 14.21 MB / 0.6199 GB Notification: Performance of Transformations before backend: time 5.364e-05/0.05753, allocations: 0 / 0.7833 GB, free: 14.21 MB / 0.6199 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 402 * Number of variables: 402 Notification: Performance of Generate backend data structure: time 0.006245/0.06378, allocations: 3.149 MB / 0.7863 GB, free: 10.86 MB / 0.6199 GB Notification: Performance of prepare preOptimizeDAE: time 4.363e-05/0.06382, allocations: 8.031 kB / 0.7864 GB, free: 10.85 MB / 0.6199 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.0004376/0.06426, allocations: 247.4 kB / 0.7866 GB, free: 10.61 MB / 0.6199 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.001742/0.066, allocations: 0.9813 MB / 0.7875 GB, free: 9.59 MB / 0.6199 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 0.0001678/0.06617, allocations: 127.4 kB / 0.7877 GB, free: 9.465 MB / 0.6199 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.000345/0.06651, allocations: 196.2 kB / 0.7879 GB, free: 9.273 MB / 0.6199 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.004066/0.07058, allocations: 2.244 MB / 0.79 GB, free: 6.863 MB / 0.6199 GB Notification: Performance of preOpt findStateOrder (simulation): time 9.728e-05/0.07068, allocations: 39.72 kB / 0.7901 GB, free: 6.824 MB / 0.6199 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 0.0001615/0.07084, allocations: 67.61 kB / 0.7902 GB, free: 6.762 MB / 0.6199 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 4.21e-05/0.07088, allocations: 36 kB / 0.7902 GB, free: 6.727 MB / 0.6199 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.00408/0.07496, allocations: 2.028 MB / 0.7922 GB, free: 4.59 MB / 0.6199 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.009067/0.08403, allocations: 4.946 MB / 0.797 GB, free: 15.53 MB / 0.6355 GB Notification: Performance of preOpt comSubExp (simulation): time 0.004005/0.08803, allocations: 1.981 MB / 0.7989 GB, free: 13.39 MB / 0.6355 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.002262/0.09029, allocations: 1.262 MB / 0.8002 GB, free: 12 MB / 0.6355 GB Notification: Performance of preOpt evalFunc (simulation): time 9.987e-05/0.09039, allocations: 23.98 kB / 0.8002 GB, free: 11.97 MB / 0.6355 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.003983/0.09438, allocations: 2.98 MB / 0.8031 GB, free: 8.617 MB / 0.6355 GB Notification: Performance of pre-optimization done (n=264): time 4.508e-06/0.09438, allocations: 4 kB / 0.8031 GB, free: 8.613 MB / 0.6355 GB Notification: Performance of matching and sorting (n=282): time 0.01861/0.113, allocations: 10.2 MB / 0.8131 GB, free: 13.72 MB / 0.6512 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.001198/0.1142, allocations: 1.648 MB / 0.8147 GB, free: 11.7 MB / 0.6512 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.001984/0.1162, allocations: 1.21 MB / 0.8158 GB, free: 10.47 MB / 0.6512 GB Notification: Performance of collectPreVariables (initialization): time 0.0003051/0.1165, allocations: 117.7 kB / 0.816 GB, free: 10.35 MB / 0.6512 GB Notification: Performance of collectInitialEqns (initialization): time 0.0007645/0.1172, allocations: 0.712 MB / 0.8167 GB, free: 9.633 MB / 0.6512 GB Notification: Performance of collectInitialBindings (initialization): time 0.001078/0.1183, allocations: 0.9106 MB / 0.8175 GB, free: 8.715 MB / 0.6512 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0008105/0.1191, allocations: 475.1 kB / 0.818 GB, free: 8.242 MB / 0.6512 GB Notification: Performance of setup shared object (initialization): time 0.0001753/0.1193, allocations: 304.9 kB / 0.8183 GB, free: 7.945 MB / 0.6512 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.002682/0.122, allocations: 1.624 MB / 0.8199 GB, free: 6.164 MB / 0.6512 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.003472/0.1255, allocations: 2.442 MB / 0.8223 GB, free: 3.223 MB / 0.6512 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.01163/0.1371, allocations: 6.577 MB / 0.8287 GB, free: 11.79 MB / 0.6668 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 3.283e-05/0.1371, allocations: 11.94 kB / 0.8287 GB, free: 11.78 MB / 0.6668 GB Notification: Performance of matching and sorting (n=426) (initialization): time 0.007968/0.1451, allocations: 4.503 MB / 0.8331 GB, free: 6.977 MB / 0.6668 GB Notification: Performance of prepare postOptimizeDAE: time 0.0005252/0.1456, allocations: 0.6727 MB / 0.8337 GB, free: 6.156 MB / 0.6668 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 3.562e-05/0.1457, allocations: 20 kB / 0.8338 GB, free: 6.137 MB / 0.6668 GB Notification: Performance of postOpt tearingSystem (initialization): time 6.284e-05/0.1457, allocations: 36 kB / 0.8338 GB, free: 6.102 MB / 0.6668 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.002378/0.1481, allocations: 0.6245 MB / 0.8344 GB, free: 5.477 MB / 0.6668 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 6.148e-05/0.1482, allocations: 47.86 kB / 0.8345 GB, free: 5.43 MB / 0.6668 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.001664/0.1498, allocations: 163.8 kB / 0.8346 GB, free: 5.27 MB / 0.6668 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.0002224/0.15, allocations: 136 kB / 0.8347 GB, free: 5.137 MB / 0.6668 GB Warning: Assuming fixed start value for the following 84 variables: ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 174 ($PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (402): * Single equations (assignments): 378 * Array equations: 0 * Algorithm blocks: 24 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.001989/0.152, allocations: 1.387 MB / 0.8361 GB, free: 3.648 MB / 0.6668 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0004062/0.1524, allocations: 230.6 kB / 0.8363 GB, free: 3.422 MB / 0.6668 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.0004074/0.1528, allocations: 208.6 kB / 0.8365 GB, free: 3.219 MB / 0.6668 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 2.367e-05/0.1529, allocations: 24 kB / 0.8365 GB, free: 3.195 MB / 0.6668 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 1.793e-05/0.1529, allocations: 4 kB / 0.8365 GB, free: 3.191 MB / 0.6668 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 2.975e-05/0.1529, allocations: 19.89 kB / 0.8366 GB, free: 3.172 MB / 0.6668 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.01024/0.1632, allocations: 5.953 MB / 0.8424 GB, free: 12.95 MB / 0.6824 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 1.139e-05/0.1632, allocations: 4 kB / 0.8424 GB, free: 12.95 MB / 0.6824 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.002275/0.1654, allocations: 439.4 kB / 0.8428 GB, free: 12.52 MB / 0.6824 GB Notification: Performance of postOpt tearingSystem (simulation): time 1.616e-05/0.1655, allocations: 15.94 kB / 0.8428 GB, free: 12.5 MB / 0.6824 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0002366/0.1657, allocations: 103.9 kB / 0.8429 GB, free: 12.4 MB / 0.6824 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 1.46e-05/0.1657, allocations: 8 kB / 0.8429 GB, free: 12.39 MB / 0.6824 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 5.17e-06/0.1657, allocations: 4 kB / 0.8429 GB, free: 12.39 MB / 0.6824 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.009474/0.1752, allocations: 5.888 MB / 0.8487 GB, free: 6.098 MB / 0.6824 GB Notification: Performance of postOpt removeConstants (simulation): time 0.001166/0.1764, allocations: 434.3 kB / 0.8491 GB, free: 5.672 MB / 0.6824 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0004663/0.1768, allocations: 124 kB / 0.8492 GB, free: 5.551 MB / 0.6824 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.001333/0.1782, allocations: 115.9 kB / 0.8493 GB, free: 5.438 MB / 0.6824 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0006031/0.1788, allocations: 263.3 kB / 0.8496 GB, free: 5.18 MB / 0.6824 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 0.0001884/0.1789, allocations: 99.94 kB / 0.8497 GB, free: 5.082 MB / 0.6824 GB Notification: Performance of sorting global known variables: time 0.001275/0.1802, allocations: 0.7913 MB / 0.8504 GB, free: 4.289 MB / 0.6824 GB Notification: Performance of sort global known variables: time 6e-08/0.1802, allocations: 0 / 0.8504 GB, free: 4.289 MB / 0.6824 GB Notification: Performance of remove unused functions: time 0.002103/0.1823, allocations: 0.6523 MB / 0.8511 GB, free: 3.637 MB / 0.6824 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC) * Number of discrete variables: 108 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising) * Number of discrete states: 96 (patient.periodicDose.pulse.count,patient.peripheral.Cmin,$whenCondition41,patient.peripheral.Cmax,$whenCondition40,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition39,patient.periodicDose.absorptionLumen.Cmax,$whenCondition38,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition37,patient.central.Cmax,$whenCondition36,patient.central.rising,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmin,$whenCondition34,patient_high.peripheral.Cmax,$whenCondition33,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition32,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition31,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition30,patient_high.central.Cmax,$whenCondition29,patient_high.central.rising,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmin,$whenCondition27,patient_low.peripheral.Cmax,$whenCondition26,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition25,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition24,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition23,patient_low.central.Cmax,$whenCondition22,patient_low.central.rising,ref.periodicDose.pulse.count,ref.peripheral.Cmin,$whenCondition20,ref.peripheral.Cmax,$whenCondition19,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition18,ref.periodicDose.absorptionLumen.Cmax,$whenCondition17,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition16,ref.central.Cmax,$whenCondition15,ref.central.rising,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmin,$whenCondition13,ref_high.peripheral.Cmax,$whenCondition12,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition11,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition10,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition9,ref_high.central.Cmax,$whenCondition8,ref_high.central.rising,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmin,$whenCondition6,ref_low.peripheral.Cmax,$whenCondition5,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition4,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition3,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition2,ref_low.central.Cmax,$whenCondition1,ref_low.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (228): * Single equations (assignments): 198 * Array equations: 0 * Algorithm blocks: 18 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.000523/0.1828, allocations: 345.5 kB / 0.8514 GB, free: 3.293 MB / 0.6824 GB Notification: Performance of simCode: created initialization part: time 0.2991/0.482, allocations: 4.827 MB / 0.8561 GB, free: 102.6 MB / 0.6824 GB Notification: Performance of simCode: created event and clocks part: time 9.197e-06/0.482, allocations: 2.094 kB / 0.8561 GB, free: 102.6 MB / 0.6824 GB Notification: Performance of simCode: created simulation system equations: time 0.00349/0.4855, allocations: 2.791 MB / 0.8588 GB, free: 100.9 MB / 0.6824 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.003749/0.4892, allocations: 0.6772 MB / 0.8595 GB, free: 100.8 MB / 0.6824 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.008133/0.4974, allocations: 6.058 MB / 0.8654 GB, free: 97.25 MB / 0.6824 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.0007409/0.4981, allocations: 0.8788 MB / 0.8663 GB, free: 97.05 MB / 0.6824 GB Notification: Performance of simCode: alias equations: time 0.001534/0.4996, allocations: 243.8 kB / 0.8665 GB, free: 97.02 MB / 0.6824 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.0004218/0.5001, allocations: 160.6 kB / 0.8667 GB, free: 97.01 MB / 0.6824 GB Notification: Performance of SimCode: time 2.534e-06/0.5001, allocations: 0 / 0.8667 GB, free: 97.01 MB / 0.6824 GB Notification: Performance of Templates: time 0.07142/0.5715, allocations: 35.88 MB / 0.9017 GB, free: 82.98 MB / 0.6824 GB " [Timeout remaining time 659] make -j1 -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.sim & ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic -abortSlowSimulation -alarm=240 -lv LOG_STATS > Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 10.84834501100704]