Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.001004/0.001004, allocations: 84.53 kB / 19.93 MB, free: 4.609 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.001454/0.001454, allocations: 173.9 kB / 23.21 MB, free: 1.328 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 0.9254/0.9254, allocations: 177.1 MB / 203.5 MB, free: 5.758 MB / 186.7 MB " [Timeout remaining time 179] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 1.628/1.628, allocations: 273.5 MB / 0.5209 GB, free: 15.04 MB / 458.7 MB " [Timeout remaining time 178] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") [Timeout 660] "Notification: Performance of FrontEnd - loaded program: time 2.675e-06/2.675e-06, allocations: 0 / 0.7558 GB, free: 10.77 MB / 0.5887 GB Notification: Performance of FrontEnd - Absyn->SCode: time 3.866e-05/4.134e-05, allocations: 5.234 kB / 0.7558 GB, free: 10.76 MB / 0.5887 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic): time 0.01251/0.01256, allocations: 11.69 MB / 0.7672 GB, free: 15.09 MB / 0.6043 GB Notification: Performance of NFInst.instExpressions: time 0.008132/0.02069, allocations: 2.662 MB / 0.7698 GB, free: 12.44 MB / 0.6043 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.001636/0.02232, allocations: 27.94 kB / 0.7698 GB, free: 12.41 MB / 0.6043 GB Notification: Performance of NFTyping.typeComponents: time 0.0007957/0.02312, allocations: 308.8 kB / 0.7701 GB, free: 12.11 MB / 0.6043 GB Notification: Performance of NFTyping.typeBindings: time 0.002475/0.02559, allocations: 0.9063 MB / 0.771 GB, free: 11.19 MB / 0.6043 GB Notification: Performance of NFTyping.typeClassSections: time 0.001632/0.02723, allocations: 0.6787 MB / 0.7717 GB, free: 10.51 MB / 0.6043 GB Notification: Performance of NFFlatten.flatten: time 0.003534/0.03076, allocations: 3.258 MB / 0.7748 GB, free: 7.238 MB / 0.6043 GB Notification: Performance of NFFlatten.resolveConnections: time 0.001113/0.03187, allocations: 454.6 kB / 0.7753 GB, free: 6.766 MB / 0.6043 GB Notification: Performance of NFEvalConstants.evaluate: time 0.002228/0.0341, allocations: 1.653 MB / 0.7769 GB, free: 5.109 MB / 0.6043 GB Notification: Performance of NFSimplifyModel.simplify: time 0.001417/0.03552, allocations: 0.9074 MB / 0.7778 GB, free: 4.199 MB / 0.6043 GB Notification: Performance of NFPackage.collectConstants: time 0.0004242/0.03594, allocations: 284 kB / 0.778 GB, free: 3.922 MB / 0.6043 GB Notification: Performance of NFFlatten.collectFunctions: time 0.0004749/0.03642, allocations: 284 kB / 0.7783 GB, free: 3.645 MB / 0.6043 GB Notification: Performance of NFScalarize.scalarize: time 0.0003872/0.03681, allocations: 0.502 MB / 0.7788 GB, free: 3.141 MB / 0.6043 GB Notification: Performance of NFVerifyModel.verify: time 0.00121/0.03802, allocations: 0.9515 MB / 0.7797 GB, free: 2.188 MB / 0.6043 GB Notification: Performance of NFConvertDAE.convert: time 0.003355/0.04137, allocations: 3.089 MB / 0.7827 GB, free: 15.09 MB / 0.6199 GB Notification: Performance of FrontEnd - DAE generated: time 7.784e-06/0.04138, allocations: 0 / 0.7827 GB, free: 15.09 MB / 0.6199 GB Notification: Performance of FrontEnd: time 2.855e-06/0.04138, allocations: 0 / 0.7827 GB, free: 15.09 MB / 0.6199 GB Notification: Performance of Transformations before backend: time 5.051e-05/0.04143, allocations: 0 / 0.7827 GB, free: 15.09 MB / 0.6199 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 402 * Number of variables: 402 Notification: Performance of Generate backend data structure: time 0.004944/0.04638, allocations: 3.152 MB / 0.7858 GB, free: 11.74 MB / 0.6199 GB Notification: Performance of prepare preOptimizeDAE: time 5.967e-05/0.04644, allocations: 8.031 kB / 0.7858 GB, free: 11.73 MB / 0.6199 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.0004096/0.04685, allocations: 251.4 kB / 0.7861 GB, free: 11.48 MB / 0.6199 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.001678/0.04852, allocations: 0.9891 MB / 0.787 GB, free: 10.46 MB / 0.6199 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 0.0001081/0.04863, allocations: 123.3 kB / 0.7872 GB, free: 10.34 MB / 0.6199 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.0003168/0.04895, allocations: 192.2 kB / 0.7873 GB, free: 10.15 MB / 0.6199 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.003922/0.05287, allocations: 2.256 MB / 0.7895 GB, free: 7.727 MB / 0.6199 GB Notification: Performance of preOpt findStateOrder (simulation): time 7.325e-05/0.05294, allocations: 27.8 kB / 0.7896 GB, free: 7.699 MB / 0.6199 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 0.0001091/0.05305, allocations: 71.98 kB / 0.7896 GB, free: 7.629 MB / 0.6199 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 2.253e-05/0.05308, allocations: 36 kB / 0.7897 GB, free: 7.594 MB / 0.6199 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.002111/0.05519, allocations: 2.02 MB / 0.7916 GB, free: 5.465 MB / 0.6199 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.005338/0.06052, allocations: 4.946 MB / 0.7965 GB, free: 420 kB / 0.6199 GB Notification: Performance of preOpt comSubExp (simulation): time 0.002144/0.06267, allocations: 1.984 MB / 0.7984 GB, free: 14.27 MB / 0.6355 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.001091/0.06376, allocations: 1.261 MB / 0.7996 GB, free: 12.88 MB / 0.6355 GB Notification: Performance of preOpt evalFunc (simulation): time 7.278e-05/0.06383, allocations: 35.88 kB / 0.7997 GB, free: 12.84 MB / 0.6355 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.002136/0.06597, allocations: 2.981 MB / 0.8026 GB, free: 9.492 MB / 0.6355 GB Notification: Performance of pre-optimization done (n=264): time 3.878e-06/0.06597, allocations: 0 / 0.8026 GB, free: 9.492 MB / 0.6355 GB Notification: Performance of matching and sorting (n=282): time 0.01014/0.07611, allocations: 10.2 MB / 0.8126 GB, free: 14.6 MB / 0.6512 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.0005413/0.07665, allocations: 1.648 MB / 0.8142 GB, free: 12.57 MB / 0.6512 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.001149/0.0778, allocations: 1.206 MB / 0.8153 GB, free: 11.35 MB / 0.6512 GB Notification: Performance of collectPreVariables (initialization): time 0.0001284/0.07793, allocations: 121.7 kB / 0.8155 GB, free: 11.23 MB / 0.6512 GB Notification: Performance of collectInitialEqns (initialization): time 0.0007528/0.07868, allocations: 0.7082 MB / 0.8162 GB, free: 10.51 MB / 0.6512 GB Notification: Performance of collectInitialBindings (initialization): time 0.0005159/0.0792, allocations: 0.9144 MB / 0.817 GB, free: 9.59 MB / 0.6512 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0004547/0.07965, allocations: 475.1 kB / 0.8175 GB, free: 9.117 MB / 0.6512 GB Notification: Performance of setup shared object (initialization): time 8.232e-05/0.07973, allocations: 305.1 kB / 0.8178 GB, free: 8.816 MB / 0.6512 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.00142/0.08115, allocations: 1.628 MB / 0.8194 GB, free: 7.031 MB / 0.6512 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.001782/0.08294, allocations: 2.438 MB / 0.8218 GB, free: 4.094 MB / 0.6512 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.006056/0.08899, allocations: 6.573 MB / 0.8282 GB, free: 12.67 MB / 0.6668 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 2.52e-05/0.08902, allocations: 11.94 kB / 0.8282 GB, free: 12.66 MB / 0.6668 GB Notification: Performance of matching and sorting (n=426) (initialization): time 0.004478/0.09349, allocations: 4.495 MB / 0.8326 GB, free: 7.859 MB / 0.6668 GB Notification: Performance of prepare postOptimizeDAE: time 0.0002715/0.09377, allocations: 0.6805 MB / 0.8332 GB, free: 7.031 MB / 0.6668 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 2.255e-05/0.09379, allocations: 20.06 kB / 0.8333 GB, free: 7.012 MB / 0.6668 GB Notification: Performance of postOpt tearingSystem (initialization): time 4.363e-05/0.09383, allocations: 40 kB / 0.8333 GB, free: 6.973 MB / 0.6668 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.001127/0.09496, allocations: 0.6168 MB / 0.8339 GB, free: 6.355 MB / 0.6668 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 3.829e-05/0.095, allocations: 55.84 kB / 0.834 GB, free: 6.301 MB / 0.6668 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.001014/0.09601, allocations: 155.8 kB / 0.8341 GB, free: 6.148 MB / 0.6668 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.000131/0.09614, allocations: 132 kB / 0.8342 GB, free: 6.02 MB / 0.6668 GB Warning: Assuming fixed start value for the following 84 variables: ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 174 ($PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (402): * Single equations (assignments): 378 * Array equations: 0 * Algorithm blocks: 24 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.001498/0.09764, allocations: 1.396 MB / 0.8356 GB, free: 4.52 MB / 0.6668 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0004984/0.09814, allocations: 234.6 kB / 0.8358 GB, free: 4.289 MB / 0.6668 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.0002243/0.09836, allocations: 204.9 kB / 0.836 GB, free: 4.086 MB / 0.6668 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 1.291e-05/0.09838, allocations: 31.98 kB / 0.836 GB, free: 4.055 MB / 0.6668 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 2e-05/0.0984, allocations: 0 / 0.836 GB, free: 4.055 MB / 0.6668 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 1.219e-05/0.09841, allocations: 11.97 kB / 0.8361 GB, free: 4.043 MB / 0.6668 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.005631/0.104, allocations: 5.96 MB / 0.8419 GB, free: 13.82 MB / 0.6824 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 6.361e-06/0.104, allocations: 4 kB / 0.8419 GB, free: 13.81 MB / 0.6824 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.001055/0.1051, allocations: 451.4 kB / 0.8423 GB, free: 13.37 MB / 0.6824 GB Notification: Performance of postOpt tearingSystem (simulation): time 1.252e-05/0.1051, allocations: 12 kB / 0.8423 GB, free: 13.36 MB / 0.6824 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0001247/0.1052, allocations: 91.95 kB / 0.8424 GB, free: 13.27 MB / 0.6824 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 9.958e-06/0.1052, allocations: 11.98 kB / 0.8424 GB, free: 13.26 MB / 0.6824 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 3.507e-06/0.1053, allocations: 4 kB / 0.8424 GB, free: 13.25 MB / 0.6824 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.005248/0.1105, allocations: 5.888 MB / 0.8482 GB, free: 6.961 MB / 0.6824 GB Notification: Performance of postOpt removeConstants (simulation): time 0.0006895/0.1112, allocations: 442.3 kB / 0.8486 GB, free: 6.531 MB / 0.6824 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0002872/0.1115, allocations: 116 kB / 0.8487 GB, free: 6.418 MB / 0.6824 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.0006621/0.1121, allocations: 111.9 kB / 0.8488 GB, free: 6.309 MB / 0.6824 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0003337/0.1125, allocations: 251.3 kB / 0.8491 GB, free: 6.062 MB / 0.6824 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 0.0001013/0.1126, allocations: 99.95 kB / 0.8491 GB, free: 5.965 MB / 0.6824 GB Notification: Performance of sorting global known variables: time 0.001172/0.1137, allocations: 0.7874 MB / 0.8499 GB, free: 5.176 MB / 0.6824 GB Notification: Performance of sort global known variables: time 7e-08/0.1137, allocations: 0 / 0.8499 GB, free: 5.176 MB / 0.6824 GB Notification: Performance of remove unused functions: time 0.001546/0.1153, allocations: 0.6601 MB / 0.8506 GB, free: 4.516 MB / 0.6824 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC) * Number of discrete variables: 108 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising) * Number of discrete states: 96 (patient.periodicDose.pulse.count,patient.peripheral.Cmin,$whenCondition41,patient.peripheral.Cmax,$whenCondition40,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition39,patient.periodicDose.absorptionLumen.Cmax,$whenCondition38,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition37,patient.central.Cmax,$whenCondition36,patient.central.rising,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmin,$whenCondition34,patient_high.peripheral.Cmax,$whenCondition33,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition32,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition31,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition30,patient_high.central.Cmax,$whenCondition29,patient_high.central.rising,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmin,$whenCondition27,patient_low.peripheral.Cmax,$whenCondition26,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition25,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition24,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition23,patient_low.central.Cmax,$whenCondition22,patient_low.central.rising,ref.periodicDose.pulse.count,ref.peripheral.Cmin,$whenCondition20,ref.peripheral.Cmax,$whenCondition19,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition18,ref.periodicDose.absorptionLumen.Cmax,$whenCondition17,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition16,ref.central.Cmax,$whenCondition15,ref.central.rising,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmin,$whenCondition13,ref_high.peripheral.Cmax,$whenCondition12,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition11,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition10,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition9,ref_high.central.Cmax,$whenCondition8,ref_high.central.rising,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmin,$whenCondition6,ref_low.peripheral.Cmax,$whenCondition5,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition4,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition3,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition2,ref_low.central.Cmax,$whenCondition1,ref_low.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (228): * Single equations (assignments): 198 * Array equations: 0 * Algorithm blocks: 18 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0003291/0.1156, allocations: 348.5 kB / 0.8509 GB, free: 4.172 MB / 0.6824 GB Notification: Performance of simCode: created initialization part: time 0.3355/0.4511, allocations: 4.828 MB / 0.8556 GB, free: 103.9 MB / 0.6824 GB Notification: Performance of simCode: created event and clocks part: time 1.347e-05/0.4511, allocations: 1.062 kB / 0.8556 GB, free: 103.9 MB / 0.6824 GB Notification: Performance of simCode: created simulation system equations: time 0.003304/0.4544, allocations: 2.73 MB / 0.8583 GB, free: 102.2 MB / 0.6824 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.002614/0.4571, allocations: 0.682 MB / 0.8589 GB, free: 102.1 MB / 0.6824 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.006395/0.4635, allocations: 6.101 MB / 0.8649 GB, free: 98.62 MB / 0.6824 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.000584/0.464, allocations: 0.876 MB / 0.8658 GB, free: 98.43 MB / 0.6824 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.0003872/0.4644, allocations: 174.5 kB / 0.8659 GB, free: 98.42 MB / 0.6824 GB Notification: Performance of SimCode: time 1.292e-06/0.4644, allocations: 0 / 0.8659 GB, free: 98.42 MB / 0.6824 GB Notification: Performance of Templates: time 0.0438/0.5082, allocations: 31.67 MB / 0.8969 GB, free: 85.8 MB / 0.6824 GB " [Timeout remaining time 659] make -j1 -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.sim & ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic > Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 8.574022819055244]