Environment - simulationEnvironment: startTime=0 stopTime=86400 tolerance=1e-06 numberOfIntervals=86400 stepSize=1 Regular simulation: ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.Patient_PK_2C_Ibuprofen -abortSlowSimulation -alarm=240 -lv LOG_STATS LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1189.000000 | | | | ((periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= periodicDose.absorptionLumen.M, has value: -4.50184e-11" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable] | | | | The following assertion has been violated at time 1209.000000 | | | | ((periodicDose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= periodicDose.absorptionLumen.C, has value: -1.04572e-09" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable] | | | | The following assertion has been violated at time 7531.819467 | | | | ((periodicDose.absorptionLumen.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= periodicDose.absorptionLumen.Cmin, has value: -5.08475e-09" LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0.00216763s reading init.xml | | | | | | 0.000187252s reading info.xml | | | | | | 8.5961e-05s [ 0.1%] pre-initialization | | | | | | 8.2385e-05s [ 0.1%] initialization | | | | | | 1.272e-06s [ 0.0%] steps | | | | | | 0.015911s [ 11.8%] solver (excl. callbacks) | | | | | | 0s [ 0.0%] creating output-file | | | | | | 0.0177849s [ 13.2%] event-handling | | | | | | 0.00581633s [ 4.3%] overhead | | | | | | 0.0953287s [ 70.6%] simulation | | | | | | 0.135011s [100.0%] total | | | | | events | | | | | | 33 state events | | | | | | 0 time events | | | | | solver: dassl | | | | | | 822 steps taken | | | | | | 1028 calls of functionODE | | | | | | 469 evaluations of jacobian | | | | | | 23 error test failures | | | | | | 0 convergence test failures | | | | | | 0.000605682s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.