Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.001851/0.001851, allocations: 105.5 kB / 18.95 MB, free: 1.18 MB / 13.93 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.002665/0.002665, allocations: 222.8 kB / 22.25 MB, free: 3.586 MB / 13.93 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 1.657/1.657, allocations: 230.6 MB / 256 MB, free: 9.598 MB / 202.7 MB " [Timeout remaining time 178] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 3.691/3.691, allocations: 335.2 MB / 0.6325 GB, free: 7.23 MB / 442.7 MB " [Timeout remaining time 176] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") [Timeout 660] "Notification: Pharmacolibrary requested package Modelica of version 4.0.0. Modelica 4.1.0 is used instead which states that it is fully compatible without conversion script needed. Notification: Performance of FrontEnd - loaded program: time 0.003766/0.003766, allocations: 75.89 kB / 0.868 GB, free: 5.746 MB / 0.573 GB Notification: Performance of FrontEnd - Absyn->SCode: time 0.2436/0.2474, allocations: 112.8 MB / 0.9782 GB, free: 4.664 MB / 0.6824 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic): time 0.5674/0.8148, allocations: 11.66 MB / 0.9896 GB, free: 20.2 MB / 0.698 GB Notification: Performance of NFInst.instExpressions: time 0.005215/0.82, allocations: 2.67 MB / 0.9922 GB, free: 20 MB / 0.698 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.001677/0.8217, allocations: 17.47 kB / 0.9922 GB, free: 20 MB / 0.698 GB Notification: Performance of NFTyping.typeComponents: time 0.0008111/0.8225, allocations: 308.3 kB / 0.9925 GB, free: 19.83 MB / 0.698 GB Notification: Performance of NFTyping.typeBindings: time 0.002947/0.8255, allocations: 0.862 MB / 0.9933 GB, free: 19.45 MB / 0.698 GB Notification: Performance of NFTyping.typeClassSections: time 0.001845/0.8273, allocations: 0.6593 MB / 0.994 GB, free: 19.44 MB / 0.698 GB Notification: Performance of NFFlatten.flatten: time 0.004221/0.8315, allocations: 3.156 MB / 0.9971 GB, free: 18.61 MB / 0.698 GB Notification: Performance of NFFlatten.resolveConnections: time 0.0008559/0.8324, allocations: 452.2 kB / 0.9975 GB, free: 18.52 MB / 0.698 GB Notification: Performance of NFEvalConstants.evaluate: time 0.001774/0.8342, allocations: 1.082 MB / 0.9985 GB, free: 18.03 MB / 0.698 GB Notification: Performance of NFSimplifyModel.simplify: time 0.001526/0.8357, allocations: 1.056 MB / 0.9996 GB, free: 17.57 MB / 0.698 GB Notification: Performance of NFPackage.collectConstants: time 0.0003613/0.836, allocations: 289.9 kB / 0.9999 GB, free: 17.57 MB / 0.698 GB Notification: Performance of NFFlatten.collectFunctions: time 0.0004992/0.8365, allocations: 283.5 kB / 1 GB, free: 17.57 MB / 0.698 GB Notification: Performance of NFScalarize.scalarize: time 0.0003062/0.8369, allocations: 0.4941 MB / 1.001 GB, free: 17.21 MB / 0.698 GB Notification: Performance of NFVerifyModel.verify: time 0.001101/0.838, allocations: 1.106 MB / 1.002 GB, free: 16.63 MB / 0.698 GB Notification: Performance of NFConvertDAE.convert: time 0.004011/0.842, allocations: 3.013 MB / 1.005 GB, free: 15.34 MB / 0.698 GB Notification: Performance of FrontEnd - DAE generated: time 6.793e-06/0.842, allocations: 1.812 kB / 1.005 GB, free: 15.34 MB / 0.698 GB Notification: Performance of FrontEnd: time 2.725e-06/0.842, allocations: 0 / 1.005 GB, free: 15.34 MB / 0.698 GB Notification: Performance of Transformations before backend: time 0.0001306/0.8421, allocations: 4.906 kB / 1.005 GB, free: 15.33 MB / 0.698 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 402 * Number of variables: 402 Notification: Performance of Generate backend data structure: time 0.007233/0.8493, allocations: 3.17 MB / 1.008 GB, free: 13.04 MB / 0.698 GB Notification: Performance of prepare preOptimizeDAE: time 5.864e-05/0.8494, allocations: 11.45 kB / 1.008 GB, free: 13.04 MB / 0.698 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.0006238/0.85, allocations: 251.2 kB / 1.008 GB, free: 12.91 MB / 0.698 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.002049/0.8521, allocations: 0.9832 MB / 1.009 GB, free: 12.22 MB / 0.698 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 0.0001209/0.8522, allocations: 131.3 kB / 1.009 GB, free: 12.16 MB / 0.698 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.0003779/0.8526, allocations: 194.2 kB / 1.009 GB, free: 12.09 MB / 0.698 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.004845/0.8574, allocations: 2.25 MB / 1.011 GB, free: 10.75 MB / 0.698 GB Notification: Performance of preOpt findStateOrder (simulation): time 0.0001122/0.8575, allocations: 32.83 kB / 1.011 GB, free: 10.73 MB / 0.698 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 0.0001745/0.8577, allocations: 66.27 kB / 1.012 GB, free: 10.69 MB / 0.698 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 3.967e-05/0.8577, allocations: 37.81 kB / 1.012 GB, free: 10.69 MB / 0.698 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.004069/0.8618, allocations: 2.032 MB / 1.014 GB, free: 9.621 MB / 0.698 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.0117/0.8735, allocations: 4.95 MB / 1.018 GB, free: 6.438 MB / 0.698 GB Notification: Performance of preOpt comSubExp (simulation): time 0.004804/0.8783, allocations: 1.989 MB / 1.02 GB, free: 5.234 MB / 0.698 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.002658/0.881, allocations: 1.264 MB / 1.022 GB, free: 4.316 MB / 0.698 GB Notification: Performance of preOpt evalFunc (simulation): time 0.0001068/0.8811, allocations: 23.61 kB / 1.022 GB, free: 4.316 MB / 0.698 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.004741/0.8858, allocations: 2.966 MB / 1.024 GB, free: 2.02 MB / 0.698 GB Notification: Performance of pre-optimization done (n=264): time 5.951e-06/0.8858, allocations: 0.5625 kB / 1.024 GB, free: 2.02 MB / 0.698 GB Notification: Performance of matching and sorting (n=282): time 0.0196/0.9054, allocations: 10.19 MB / 1.034 GB, free: 11.03 MB / 0.7137 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.001262/0.9067, allocations: 1.651 MB / 1.036 GB, free: 9.09 MB / 0.7137 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.002156/0.9088, allocations: 1.206 MB / 1.037 GB, free: 8.59 MB / 0.7137 GB Notification: Performance of collectPreVariables (initialization): time 0.0006853/0.9095, allocations: 117.3 kB / 1.037 GB, free: 8.508 MB / 0.7137 GB Notification: Performance of collectInitialEqns (initialization): time 0.0007931/0.9103, allocations: 0.7132 MB / 1.038 GB, free: 7.941 MB / 0.7137 GB Notification: Performance of collectInitialBindings (initialization): time 0.001282/0.9116, allocations: 0.9147 MB / 1.039 GB, free: 7.211 MB / 0.7137 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0008229/0.9124, allocations: 478.2 kB / 1.039 GB, free: 6.992 MB / 0.7137 GB Notification: Performance of setup shared object (initialization): time 0.0001735/0.9126, allocations: 305.1 kB / 1.04 GB, free: 6.691 MB / 0.7137 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.002806/0.9154, allocations: 1.628 MB / 1.041 GB, free: 5.375 MB / 0.7137 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.003947/0.9193, allocations: 2.437 MB / 1.044 GB, free: 3.012 MB / 0.7137 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.01209/0.9314, allocations: 6.563 MB / 1.05 GB, free: 13.45 MB / 0.7293 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 5.373e-05/0.9315, allocations: 6.906 kB / 1.05 GB, free: 13.45 MB / 0.7293 GB Notification: Performance of matching and sorting (n=426) (initialization): time 0.009258/0.9407, allocations: 4.501 MB / 1.054 GB, free: 10.36 MB / 0.7293 GB Notification: Performance of prepare postOptimizeDAE: time 0.0005849/0.9413, allocations: 0.6736 MB / 1.055 GB, free: 9.566 MB / 0.7293 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 5.039e-05/0.9414, allocations: 22.5 kB / 1.055 GB, free: 9.566 MB / 0.7293 GB Notification: Performance of postOpt tearingSystem (initialization): time 7.569e-05/0.9415, allocations: 40.22 kB / 1.055 GB, free: 9.562 MB / 0.7293 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.002425/0.9439, allocations: 0.629 MB / 1.056 GB, free: 9.395 MB / 0.7293 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 6.422e-05/0.9439, allocations: 47.67 kB / 1.056 GB, free: 9.383 MB / 0.7293 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.002618/0.9466, allocations: 149.9 kB / 1.056 GB, free: 9.312 MB / 0.7293 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.0003044/0.9469, allocations: 135.1 kB / 1.056 GB, free: 9.281 MB / 0.7293 GB Warning: Assuming fixed start value for the following 84 variables: ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 174 ($PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (402): * Single equations (assignments): 378 * Array equations: 0 * Algorithm blocks: 24 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.002625/0.9495, allocations: 1.409 MB / 1.057 GB, free: 8.074 MB / 0.7293 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0007296/0.9502, allocations: 234.9 kB / 1.058 GB, free: 7.957 MB / 0.7293 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.0005933/0.9508, allocations: 208.7 kB / 1.058 GB, free: 7.793 MB / 0.7293 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 3.482e-05/0.9509, allocations: 27.09 kB / 1.058 GB, free: 7.789 MB / 0.7293 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 4.632e-05/0.9509, allocations: 1.375 kB / 1.058 GB, free: 7.789 MB / 0.7293 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 2.869e-05/0.9509, allocations: 13.33 kB / 1.058 GB, free: 7.777 MB / 0.7293 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.01097/0.9619, allocations: 5.956 MB / 1.064 GB, free: 3.582 MB / 0.7293 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 1.009e-05/0.9619, allocations: 1.156 kB / 1.064 GB, free: 3.582 MB / 0.7293 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.002149/0.9641, allocations: 447 kB / 1.064 GB, free: 3.473 MB / 0.7293 GB Notification: Performance of postOpt tearingSystem (simulation): time 1.851e-05/0.9641, allocations: 8.031 kB / 1.064 GB, free: 3.473 MB / 0.7293 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0002429/0.9643, allocations: 101.8 kB / 1.064 GB, free: 3.414 MB / 0.7293 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 1.606e-05/0.9643, allocations: 16.72 kB / 1.064 GB, free: 3.406 MB / 0.7293 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 2.424e-06/0.9643, allocations: 1.062 kB / 1.064 GB, free: 3.406 MB / 0.7293 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.00951/0.9738, allocations: 5.89 MB / 1.07 GB, free: 15.2 MB / 0.7449 GB Notification: Performance of postOpt removeConstants (simulation): time 0.001707/0.9756, allocations: 433.3 kB / 1.07 GB, free: 14.87 MB / 0.7449 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0007867/0.9763, allocations: 116.7 kB / 1.071 GB, free: 14.81 MB / 0.7449 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.001579/0.9779, allocations: 128 kB / 1.071 GB, free: 14.75 MB / 0.7449 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0005948/0.9785, allocations: 257.4 kB / 1.071 GB, free: 14.58 MB / 0.7449 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 0.000244/0.9788, allocations: 94.42 kB / 1.071 GB, free: 14.55 MB / 0.7449 GB Notification: Performance of sorting global known variables: time 0.001515/0.9803, allocations: 0.7899 MB / 1.072 GB, free: 14.11 MB / 0.7449 GB Notification: Performance of sort global known variables: time 1.1e-07/0.9803, allocations: 0 / 1.072 GB, free: 14.11 MB / 0.7449 GB Notification: Performance of remove unused functions: time 0.002821/0.9831, allocations: 0.6572 MB / 1.072 GB, free: 14.04 MB / 0.7449 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC) * Number of discrete variables: 108 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising) * Number of discrete states: 96 (patient.periodicDose.pulse.count,patient.peripheral.Cmin,$whenCondition41,patient.peripheral.Cmax,$whenCondition40,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition39,patient.periodicDose.absorptionLumen.Cmax,$whenCondition38,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition37,patient.central.Cmax,$whenCondition36,patient.central.rising,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmin,$whenCondition34,patient_high.peripheral.Cmax,$whenCondition33,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition32,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition31,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition30,patient_high.central.Cmax,$whenCondition29,patient_high.central.rising,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmin,$whenCondition27,patient_low.peripheral.Cmax,$whenCondition26,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition25,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition24,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition23,patient_low.central.Cmax,$whenCondition22,patient_low.central.rising,ref.periodicDose.pulse.count,ref.peripheral.Cmin,$whenCondition20,ref.peripheral.Cmax,$whenCondition19,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition18,ref.periodicDose.absorptionLumen.Cmax,$whenCondition17,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition16,ref.central.Cmax,$whenCondition15,ref.central.rising,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmin,$whenCondition13,ref_high.peripheral.Cmax,$whenCondition12,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition11,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition10,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition9,ref_high.central.Cmax,$whenCondition8,ref_high.central.rising,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmin,$whenCondition6,ref_low.peripheral.Cmax,$whenCondition5,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition4,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition3,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition2,ref_low.central.Cmax,$whenCondition1,ref_low.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (228): * Single equations (assignments): 198 * Array equations: 0 * Algorithm blocks: 18 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0005223/0.9836, allocations: 350.9 kB / 1.073 GB, free: 13.8 MB / 0.7449 GB Notification: Performance of simCode: created initialization part: time 0.009986/0.9936, allocations: 4.839 MB / 1.078 GB, free: 9.723 MB / 0.7449 GB Notification: Performance of simCode: created event and clocks part: time 7.484e-06/0.9936, allocations: 0 / 1.078 GB, free: 9.723 MB / 0.7449 GB Notification: Performance of simCode: created simulation system equations: time 0.006365/1, allocations: 2.791 MB / 1.08 GB, free: 6.605 MB / 0.7449 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.006661/1.007, allocations: 0.6826 MB / 1.081 GB, free: 5.93 MB / 0.7449 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.01887/1.026, allocations: 7.157 MB / 1.088 GB, free: 14.61 MB / 0.7605 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.001601/1.027, allocations: 0.8779 MB / 1.089 GB, free: 13.69 MB / 0.7605 GB Notification: Performance of simCode: alias equations: time 0.002565/1.03, allocations: 244.7 kB / 1.089 GB, free: 13.45 MB / 0.7605 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.0007107/1.03, allocations: 155.4 kB / 1.089 GB, free: 13.29 MB / 0.7605 GB Notification: Performance of SimCode: time 1.794e-06/1.03, allocations: 0 / 1.089 GB, free: 13.29 MB / 0.7605 GB Notification: Performance of Templates: time 0.08411/1.114, allocations: 39.58 MB / 1.128 GB, free: 6.922 MB / 0.7918 GB " [Timeout remaining time 659] make -j1 -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.sim & ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic -abortSlowSimulation -alarm=240 -lv LOG_STATS > Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 11.682613568846136]