Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.002558/0.002558, allocations: 105.5 kB / 18.95 MB, free: 1.18 MB / 13.93 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.002921/0.002921, allocations: 215.6 kB / 22.25 MB, free: 3.582 MB / 13.93 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 1.681/1.681, allocations: 230.6 MB / 256 MB, free: 9.613 MB / 202.7 MB " [Timeout remaining time 178] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 3.709/3.709, allocations: 335.2 MB / 0.6325 GB, free: 7.25 MB / 442.7 MB " [Timeout remaining time 176] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic,tolerance=1e-06,outputFormat="empty",numberOfIntervals=86400,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic") translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic,tolerance=1e-06,outputFormat="empty",numberOfIntervals=86400,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic") [Timeout 660] "Notification: Pharmacolibrary requested package Modelica of version 4.0.0. Modelica 4.1.0 is used instead which states that it is fully compatible without conversion script needed. Notification: Performance of FrontEnd - loaded program: time 0.00372/0.00372, allocations: 75.88 kB / 0.868 GB, free: 5.75 MB / 0.573 GB Notification: Performance of FrontEnd - Absyn->SCode: time 0.281/0.2847, allocations: 112.8 MB / 0.9782 GB, free: 4.66 MB / 0.6824 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic): time 0.5339/0.8186, allocations: 13.5 MB / 0.9914 GB, free: 20.2 MB / 0.698 GB Notification: Performance of NFInst.instExpressions: time 0.007006/0.8256, allocations: 3.418 MB / 0.9947 GB, free: 19.01 MB / 0.698 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.002714/0.8284, allocations: 32.06 kB / 0.9947 GB, free: 19 MB / 0.698 GB Notification: Performance of NFTyping.typeComponents: time 0.001839/0.8302, allocations: 0.4966 MB / 0.9952 GB, free: 18.75 MB / 0.698 GB Notification: Performance of NFTyping.typeBindings: time 0.003441/0.8336, allocations: 1.039 MB / 0.9962 GB, free: 18.1 MB / 0.698 GB Notification: Performance of NFTyping.typeClassSections: time 0.002439/0.8361, allocations: 0.9048 MB / 0.9971 GB, free: 18.04 MB / 0.698 GB Notification: Performance of NFFlatten.flatten: time 0.005351/0.8414, allocations: 3.76 MB / 1.001 GB, free: 16.58 MB / 0.698 GB Notification: Performance of NFFlatten.resolveConnections: time 0.0009853/0.8424, allocations: 0.5318 MB / 1.001 GB, free: 16.27 MB / 0.698 GB Notification: Performance of NFEvalConstants.evaluate: time 0.002151/0.8446, allocations: 1.297 MB / 1.003 GB, free: 15.62 MB / 0.698 GB Notification: Performance of NFSimplifyModel.simplify: time 0.00309/0.8477, allocations: 1.324 MB / 1.004 GB, free: 15 MB / 0.698 GB Notification: Performance of NFPackage.collectConstants: time 0.0007916/0.8485, allocations: 333.4 kB / 1.004 GB, free: 15 MB / 0.698 GB Notification: Performance of NFFlatten.collectFunctions: time 0.001669/0.8501, allocations: 477.5 kB / 1.005 GB, free: 14.95 MB / 0.698 GB Notification: Performance of NFScalarize.scalarize: time 0.0006266/0.8507, allocations: 0.6967 MB / 1.005 GB, free: 14.49 MB / 0.698 GB Notification: Performance of NFVerifyModel.verify: time 0.002204/0.853, allocations: 1.344 MB / 1.007 GB, free: 13.75 MB / 0.698 GB Notification: Performance of NFConvertDAE.convert: time 0.006159/0.8591, allocations: 4.158 MB / 1.011 GB, free: 11.92 MB / 0.698 GB Notification: Performance of FrontEnd - DAE generated: time 6.151e-06/0.8591, allocations: 0 / 1.011 GB, free: 11.92 MB / 0.698 GB Notification: Performance of FrontEnd: time 2.475e-06/0.8591, allocations: 2.234 kB / 1.011 GB, free: 11.92 MB / 0.698 GB Notification: Performance of Transformations before backend: time 0.0001599/0.8593, allocations: 0 / 1.011 GB, free: 11.92 MB / 0.698 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 486 * Number of variables: 486 Notification: Performance of Generate backend data structure: time 0.008602/0.8679, allocations: 4.262 MB / 1.015 GB, free: 8.746 MB / 0.698 GB Notification: Performance of prepare preOptimizeDAE: time 4.552e-05/0.8679, allocations: 11.45 kB / 1.015 GB, free: 8.746 MB / 0.698 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.001721/0.8696, allocations: 462.3 kB / 1.015 GB, free: 8.531 MB / 0.698 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.003104/0.8728, allocations: 1.348 MB / 1.017 GB, free: 7.609 MB / 0.698 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 0.0001973/0.8729, allocations: 147 kB / 1.017 GB, free: 7.551 MB / 0.698 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.0004781/0.8734, allocations: 224.5 kB / 1.017 GB, free: 7.477 MB / 0.698 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.006493/0.8799, allocations: 3.654 MB / 1.021 GB, free: 5.367 MB / 0.698 GB Notification: Performance of preOpt findStateOrder (simulation): time 0.0001127/0.88, allocations: 31.91 kB / 1.021 GB, free: 5.348 MB / 0.698 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 0.000219/0.8802, allocations: 83.36 kB / 1.021 GB, free: 5.293 MB / 0.698 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 6.528e-05/0.8803, allocations: 43.38 kB / 1.021 GB, free: 5.293 MB / 0.698 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.00579/0.8861, allocations: 3.296 MB / 1.024 GB, free: 3.512 MB / 0.698 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.01304/0.8991, allocations: 5.86 MB / 1.03 GB, free: 15.92 MB / 0.7137 GB Notification: Performance of preOpt comSubExp (simulation): time 0.00587/0.905, allocations: 3.257 MB / 1.033 GB, free: 13.83 MB / 0.7137 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.003827/0.9088, allocations: 2.433 MB / 1.035 GB, free: 12.03 MB / 0.7137 GB Notification: Performance of preOpt evalFunc (simulation): time 0.0001607/0.909, allocations: 35.61 kB / 1.035 GB, free: 12.02 MB / 0.7137 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.006367/0.9154, allocations: 4.214 MB / 1.039 GB, free: 8.492 MB / 0.7137 GB Notification: Performance of pre-optimization done (n=300): time 5.911e-06/0.9154, allocations: 1.375 kB / 1.039 GB, free: 8.492 MB / 0.7137 GB Notification: Performance of matching and sorting (n=318): time 0.02891/0.9443, allocations: 17.04 MB / 1.056 GB, free: 12.38 MB / 0.7293 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.001594/0.9459, allocations: 1.982 MB / 1.058 GB, free: 10.02 MB / 0.7293 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.003861/0.9497, allocations: 1.972 MB / 1.06 GB, free: 8.926 MB / 0.7293 GB Notification: Performance of collectPreVariables (initialization): time 0.0005854/0.9503, allocations: 125.5 kB / 1.06 GB, free: 8.836 MB / 0.7293 GB Notification: Performance of collectInitialEqns (initialization): time 0.001221/0.9515, allocations: 1.043 MB / 1.061 GB, free: 7.914 MB / 0.7293 GB Notification: Performance of collectInitialBindings (initialization): time 0.001418/0.953, allocations: 1.024 MB / 1.062 GB, free: 7.008 MB / 0.7293 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0009659/0.9539, allocations: 0.5357 MB / 1.063 GB, free: 6.711 MB / 0.7293 GB Notification: Performance of setup shared object (initialization): time 0.0001622/0.9541, allocations: 302.2 kB / 1.063 GB, free: 6.414 MB / 0.7293 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.003991/0.9581, allocations: 2.813 MB / 1.066 GB, free: 4.305 MB / 0.7293 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.004961/0.963, allocations: 3.621 MB / 1.069 GB, free: 1.16 MB / 0.7293 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.01701/0.9801, allocations: 11.56 MB / 1.08 GB, free: 7.215 MB / 0.7449 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 5.273e-05/0.9801, allocations: 11.94 kB / 1.08 GB, free: 7.203 MB / 0.7449 GB Notification: Performance of matching and sorting (n=462) (initialization): time 0.01286/0.993, allocations: 7.014 MB / 1.087 GB, free: 15.74 MB / 0.7605 GB Notification: Performance of prepare postOptimizeDAE: time 0.0008411/0.9938, allocations: 1.019 MB / 1.088 GB, free: 14.5 MB / 0.7605 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 4.897e-05/0.9939, allocations: 20 kB / 1.088 GB, free: 14.48 MB / 0.7605 GB Notification: Performance of postOpt tearingSystem (initialization): time 8.003e-05/0.9939, allocations: 40 kB / 1.088 GB, free: 14.44 MB / 0.7605 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.00276/0.9967, allocations: 0.6359 MB / 1.089 GB, free: 13.8 MB / 0.7605 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 8.684e-05/0.9968, allocations: 51.8 kB / 1.089 GB, free: 13.75 MB / 0.7605 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.002965/0.9998, allocations: 163.9 kB / 1.089 GB, free: 13.59 MB / 0.7605 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.000819/1.001, allocations: 407.5 kB / 1.09 GB, free: 13.2 MB / 0.7605 GB Warning: Assuming fixed start value for the following 84 variables: patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 186 ($PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.CYP2C19.status,ref.SLC22A2.status,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.CYP2C19.status,ref_low.SLC22A2.status,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.CYP2C19.status,ref_high.SLC22A2.status,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.CYP2C19.status,patient.SLC22A2.status,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.CYP2C19.status,patient_low.SLC22A2.status,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.CYP2C19.status,patient_high.SLC22A2.status,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (426): * Single equations (assignments): 390 * Array equations: 0 * Algorithm blocks: 36 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.003517/1.004, allocations: 1.979 MB / 1.091 GB, free: 11.05 MB / 0.7605 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.00115/1.005, allocations: 334 kB / 1.092 GB, free: 10.72 MB / 0.7605 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.0007627/1.006, allocations: 275.5 kB / 1.092 GB, free: 10.45 MB / 0.7605 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 2.759e-05/1.006, allocations: 24 kB / 1.092 GB, free: 10.43 MB / 0.7605 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 3.716e-05/1.006, allocations: 4 kB / 1.092 GB, free: 10.42 MB / 0.7605 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 2.777e-05/1.006, allocations: 11.95 kB / 1.092 GB, free: 10.41 MB / 0.7605 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.01543/1.022, allocations: 9.076 MB / 1.101 GB, free: 0.9219 MB / 0.7605 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 1.278e-05/1.022, allocations: 4 kB / 1.101 GB, free: 0.918 MB / 0.7605 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.002345/1.024, allocations: 463.4 kB / 1.101 GB, free: 476 kB / 0.7605 GB Notification: Performance of postOpt tearingSystem (simulation): time 1.986e-05/1.024, allocations: 11.94 kB / 1.101 GB, free: 464 kB / 0.7605 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0003042/1.024, allocations: 123.9 kB / 1.102 GB, free: 340 kB / 0.7605 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 1.714e-05/1.024, allocations: 11.98 kB / 1.102 GB, free: 328 kB / 0.7605 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 1.134e-05/1.024, allocations: 11.94 kB / 1.102 GB, free: 316 kB / 0.7605 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.01584/1.04, allocations: 10.2 MB / 1.111 GB, free: 5.484 MB / 0.7762 GB Notification: Performance of postOpt removeConstants (simulation): time 0.002153/1.042, allocations: 0.5992 MB / 1.112 GB, free: 4.887 MB / 0.7762 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0007809/1.043, allocations: 136 kB / 1.112 GB, free: 4.754 MB / 0.7762 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.001604/1.045, allocations: 127.9 kB / 1.112 GB, free: 4.629 MB / 0.7762 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.000641/1.045, allocations: 283.3 kB / 1.113 GB, free: 4.352 MB / 0.7762 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 0.0005503/1.046, allocations: 385.9 kB / 1.113 GB, free: 3.977 MB / 0.7762 GB Notification: Performance of sorting global known variables: time 0.002338/1.048, allocations: 1.339 MB / 1.114 GB, free: 2.621 MB / 0.7762 GB Notification: Performance of sort global known variables: time 8e-08/1.048, allocations: 0 / 1.114 GB, free: 2.621 MB / 0.7762 GB Notification: Performance of remove unused functions: time 0.002959/1.051, allocations: 0.7617 MB / 1.115 GB, free: 1.859 MB / 0.7762 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC) * Number of discrete variables: 120 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,patient_high.SLC22A2.status,patient_high.CYP2C19.status,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,patient_low.SLC22A2.status,patient_low.CYP2C19.status,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising,patient.SLC22A2.status,patient.CYP2C19.status,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,ref_high.SLC22A2.status,ref_high.CYP2C19.status,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,ref_low.SLC22A2.status,ref_low.CYP2C19.status,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,ref.SLC22A2.status,ref.CYP2C19.status) * Number of discrete states: 108 (ref.periodicDose.pulse.count,ref.CYP2C19.status,ref.SLC22A2.status,ref.peripheral.Cmin,$whenCondition41,ref.peripheral.Cmax,$whenCondition40,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition39,ref.periodicDose.absorptionLumen.Cmax,$whenCondition38,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition37,ref.central.Cmax,$whenCondition36,ref.central.rising,ref_low.periodicDose.pulse.count,ref_low.CYP2C19.status,ref_low.SLC22A2.status,ref_low.peripheral.Cmin,$whenCondition34,ref_low.peripheral.Cmax,$whenCondition33,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition32,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition31,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition30,ref_low.central.Cmax,$whenCondition29,ref_low.central.rising,ref_high.periodicDose.pulse.count,ref_high.CYP2C19.status,ref_high.SLC22A2.status,ref_high.peripheral.Cmin,$whenCondition27,ref_high.peripheral.Cmax,$whenCondition26,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition25,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition24,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition23,ref_high.central.Cmax,$whenCondition22,ref_high.central.rising,patient.periodicDose.pulse.count,patient.CYP2C19.status,patient.SLC22A2.status,patient.peripheral.Cmin,$whenCondition20,patient.peripheral.Cmax,$whenCondition19,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition18,patient.periodicDose.absorptionLumen.Cmax,$whenCondition17,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition16,patient.central.Cmax,$whenCondition15,patient.central.rising,patient_low.periodicDose.pulse.count,patient_low.CYP2C19.status,patient_low.SLC22A2.status,patient_low.peripheral.Cmin,$whenCondition13,patient_low.peripheral.Cmax,$whenCondition12,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition11,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition10,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition9,patient_low.central.Cmax,$whenCondition8,patient_low.central.rising,patient_high.periodicDose.pulse.count,patient_high.CYP2C19.status,patient_high.SLC22A2.status,patient_high.peripheral.Cmin,$whenCondition6,patient_high.peripheral.Cmax,$whenCondition5,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition4,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition3,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition2,patient_high.central.Cmax,$whenCondition1,patient_high.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (252): * Single equations (assignments): 210 * Array equations: 0 * Algorithm blocks: 30 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0007558/1.052, allocations: 417.6 kB / 1.115 GB, free: 1.438 MB / 0.7762 GB Notification: Performance of simCode: created initialization part: time 0.01117/1.063, allocations: 7.943 MB / 1.123 GB, free: 8.641 MB / 0.7918 GB Notification: Performance of simCode: created event and clocks part: time 5.78e-06/1.063, allocations: 0 / 1.123 GB, free: 8.641 MB / 0.7918 GB Notification: Performance of simCode: created simulation system equations: time 0.006652/1.07, allocations: 4.676 MB / 1.128 GB, free: 3.414 MB / 0.7918 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.004973/1.075, allocations: 0.7869 MB / 1.129 GB, free: 2.645 MB / 0.7918 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.01797/1.093, allocations: 9.735 MB / 1.138 GB, free: 8.656 MB / 0.8074 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.001987/1.095, allocations: 1.272 MB / 1.139 GB, free: 7.344 MB / 0.8074 GB Notification: Performance of simCode: alias equations: time 0.001659/1.096, allocations: 254.1 kB / 1.14 GB, free: 7.094 MB / 0.8074 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.0004781/1.097, allocations: 171.4 kB / 1.14 GB, free: 6.926 MB / 0.8074 GB Notification: Performance of SimCode: time 1.352e-06/1.097, allocations: 0 / 1.14 GB, free: 6.926 MB / 0.8074 GB Notification: Performance of Templates: time 0.0916/1.188, allocations: 50.07 MB / 1.189 GB, free: 6.309 MB / 0.8543 GB " [Timeout remaining time 659] make -j1 -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic.sim & ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic -abortSlowSimulation -alarm=240 -lv LOG_STATS > Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 13.615914226975292]