Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.0008682/0.0008682, allocations: 80.94 kB / 19.94 MB, free: 4.543 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.001212/0.001212, allocations: 177 kB / 23.36 MB, free: 1.129 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 1.034/1.034, allocations: 177.1 MB / 203.8 MB, free: 5.477 MB / 186.7 MB " [Timeout remaining time 179] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 1.672/1.672, allocations: 273.5 MB / 0.5213 GB, free: 14.56 MB / 458.7 MB " [Timeout remaining time 178] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") [Timeout 660] "Notification: Performance of FrontEnd - loaded program: time 1.994e-06/1.994e-06, allocations: 0 / 0.5954 GB, free: 2.598 MB / 0.5105 GB Notification: Performance of FrontEnd - Absyn->SCode: time 1.366e-05/1.565e-05, allocations: 2.312 kB / 0.5954 GB, free: 2.594 MB / 0.5105 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic): time 0.00941/0.009426, allocations: 13.12 MB / 0.6083 GB, free: 5.52 MB / 0.5261 GB Notification: Performance of NFInst.instExpressions: time 0.005093/0.01452, allocations: 2.796 MB / 0.611 GB, free: 2.73 MB / 0.5261 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.0006306/0.01515, allocations: 23.94 kB / 0.611 GB, free: 2.707 MB / 0.5261 GB Notification: Performance of NFTyping.typeComponents: time 0.0004301/0.01558, allocations: 308.9 kB / 0.6113 GB, free: 2.402 MB / 0.5261 GB Notification: Performance of NFTyping.typeBindings: time 0.00138/0.01696, allocations: 0.9102 MB / 0.6122 GB, free: 1.484 MB / 0.5261 GB Notification: Performance of NFTyping.typeClassSections: time 0.001167/0.01813, allocations: 0.671 MB / 0.6129 GB, free: 0.8125 MB / 0.5261 GB Notification: Performance of NFFlatten.flatten: time 0.3749/0.393, allocations: 3.263 MB / 0.616 GB, free: 42.76 MB / 0.5262 GB Notification: Performance of NFFlatten.resolveConnections: time 0.000631/0.3937, allocations: 478.2 kB / 0.6165 GB, free: 42.64 MB / 0.5262 GB Notification: Performance of NFEvalConstants.evaluate: time 0.001424/0.3951, allocations: 1.653 MB / 0.6181 GB, free: 42.52 MB / 0.5262 GB Notification: Performance of NFSimplifyModel.simplify: time 0.0009753/0.3961, allocations: 0.943 MB / 0.619 GB, free: 42.41 MB / 0.5262 GB Notification: Performance of NFPackage.collectConstants: time 0.0003019/0.3964, allocations: 281.8 kB / 0.6193 GB, free: 42.41 MB / 0.5262 GB Notification: Performance of NFFlatten.collectFunctions: time 0.0003156/0.3967, allocations: 286.1 kB / 0.6196 GB, free: 42.41 MB / 0.5262 GB Notification: Performance of NFScalarize.scalarize: time 0.0002551/0.3969, allocations: 0.5082 MB / 0.6201 GB, free: 42.31 MB / 0.5262 GB Notification: Performance of NFVerifyModel.verify: time 0.0006916/0.3976, allocations: 0.9514 MB / 0.621 GB, free: 42.21 MB / 0.5262 GB Notification: Performance of NFConvertDAE.convert: time 0.001368/0.399, allocations: 1.907 MB / 0.6229 GB, free: 41.62 MB / 0.5262 GB Notification: Performance of FrontEnd - DAE generated: time 5.711e-06/0.399, allocations: 2.25 kB / 0.6229 GB, free: 41.62 MB / 0.5262 GB Notification: Performance of FrontEnd: time 1.984e-06/0.399, allocations: 1.375 kB / 0.6229 GB, free: 41.62 MB / 0.5262 GB Notification: Performance of Transformations before backend: time 1.539e-05/0.399, allocations: 0 / 0.6229 GB, free: 41.62 MB / 0.5262 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 402 * Number of variables: 402 Notification: Performance of Generate backend data structure: time 0.002231/0.4012, allocations: 3.09 MB / 0.6259 GB, free: 39.5 MB / 0.5262 GB Notification: Performance of prepare preOptimizeDAE: time 3.864e-05/0.4013, allocations: 10 kB / 0.6259 GB, free: 39.5 MB / 0.5262 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.0002901/0.4016, allocations: 286.1 kB / 0.6262 GB, free: 39.46 MB / 0.5262 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.000778/0.4024, allocations: 0.6613 MB / 0.6268 GB, free: 39.07 MB / 0.5262 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 6.073e-05/0.4024, allocations: 124.2 kB / 0.6269 GB, free: 39.02 MB / 0.5262 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.0001955/0.4026, allocations: 193.8 kB / 0.6271 GB, free: 38.96 MB / 0.5262 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.001478/0.4041, allocations: 1.711 MB / 0.6288 GB, free: 38.03 MB / 0.5262 GB Notification: Performance of preOpt findStateOrder (simulation): time 5.335e-05/0.4041, allocations: 27.53 kB / 0.6288 GB, free: 38.02 MB / 0.5262 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 7.641e-05/0.4042, allocations: 75.84 kB / 0.6289 GB, free: 37.97 MB / 0.5262 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 2.419e-05/0.4042, allocations: 36.78 kB / 0.6289 GB, free: 37.97 MB / 0.5262 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.0008393/0.4051, allocations: 1.189 MB / 0.6301 GB, free: 37.27 MB / 0.5262 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.00329/0.4084, allocations: 3.593 MB / 0.6336 GB, free: 34.97 MB / 0.5262 GB Notification: Performance of preOpt comSubExp (simulation): time 0.0009594/0.4093, allocations: 1.26 MB / 0.6348 GB, free: 34.12 MB / 0.5262 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.000449/0.4098, allocations: 0.8235 MB / 0.6356 GB, free: 33.41 MB / 0.5262 GB Notification: Performance of preOpt evalFunc (simulation): time 6.651e-05/0.4098, allocations: 44.72 kB / 0.6357 GB, free: 33.41 MB / 0.5262 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.001086/0.4109, allocations: 2.564 MB / 0.6382 GB, free: 31.09 MB / 0.5262 GB Notification: Performance of pre-optimization done (n=264): time 3.416e-06/0.4109, allocations: 0 / 0.6382 GB, free: 31.09 MB / 0.5262 GB Notification: Performance of matching and sorting (n=282): time 0.004403/0.4153, allocations: 6.434 MB / 0.6444 GB, free: 26.38 MB / 0.5262 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.0002226/0.4156, allocations: 1.652 MB / 0.6461 GB, free: 24.42 MB / 0.5262 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.0006381/0.4162, allocations: 1.005 MB / 0.647 GB, free: 24.04 MB / 0.5262 GB Notification: Performance of collectPreVariables (initialization): time 0.0001024/0.4163, allocations: 118.2 kB / 0.6472 GB, free: 23.95 MB / 0.5262 GB Notification: Performance of collectInitialEqns (initialization): time 0.0001945/0.4165, allocations: 0.5057 MB / 0.6476 GB, free: 23.59 MB / 0.5262 GB Notification: Performance of collectInitialBindings (initialization): time 0.0003629/0.4169, allocations: 0.9199 MB / 0.6485 GB, free: 22.86 MB / 0.5262 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0004124/0.4173, allocations: 490 kB / 0.649 GB, free: 22.66 MB / 0.5262 GB Notification: Performance of setup shared object (initialization): time 2.666e-05/0.4173, allocations: 307.6 kB / 0.6493 GB, free: 22.36 MB / 0.5262 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.0005394/0.4178, allocations: 1.066 MB / 0.6503 GB, free: 21.47 MB / 0.5262 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.000807/0.4186, allocations: 1.839 MB / 0.6521 GB, free: 19.58 MB / 0.5262 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.001976/0.4206, allocations: 3.771 MB / 0.6558 GB, free: 16.3 MB / 0.5262 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 1.244e-05/0.4206, allocations: 6.219 kB / 0.6558 GB, free: 16.3 MB / 0.5262 GB Notification: Performance of matching and sorting (n=426) (initialization): time 0.001811/0.4224, allocations: 2.802 MB / 0.6586 GB, free: 14.36 MB / 0.5262 GB Notification: Performance of prepare postOptimizeDAE: time 0.0001276/0.4226, allocations: 0.675 MB / 0.6592 GB, free: 13.57 MB / 0.5262 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 1.932e-05/0.4226, allocations: 22.31 kB / 0.6593 GB, free: 13.57 MB / 0.5262 GB Notification: Performance of postOpt tearingSystem (initialization): time 2.995e-05/0.4226, allocations: 40 kB / 0.6593 GB, free: 13.57 MB / 0.5262 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.001403/0.424, allocations: 0.8223 MB / 0.6601 GB, free: 13.39 MB / 0.5262 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 2.585e-05/0.4241, allocations: 50.83 kB / 0.6601 GB, free: 13.39 MB / 0.5262 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.0006565/0.4247, allocations: 141.5 kB / 0.6603 GB, free: 13.33 MB / 0.5262 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 9.915e-05/0.4248, allocations: 109.2 kB / 0.6604 GB, free: 13.3 MB / 0.5262 GB Warning: Assuming fixed start value for the following 84 variables: ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 174 ($PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (402): * Single equations (assignments): 378 * Array equations: 0 * Algorithm blocks: 24 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.0007196/0.4255, allocations: 1.241 MB / 0.6616 GB, free: 12.32 MB / 0.5262 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0002176/0.4257, allocations: 269.1 kB / 0.6618 GB, free: 12.23 MB / 0.5262 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.0001601/0.4259, allocations: 204.8 kB / 0.662 GB, free: 12.07 MB / 0.5262 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 1.051e-05/0.4259, allocations: 22.31 kB / 0.6621 GB, free: 12.07 MB / 0.5262 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 2.454e-05/0.4259, allocations: 3.281 kB / 0.6621 GB, free: 12.07 MB / 0.5262 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 1.367e-05/0.426, allocations: 16.92 kB / 0.6621 GB, free: 12.06 MB / 0.5262 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.002509/0.4285, allocations: 3.729 MB / 0.6657 GB, free: 9.148 MB / 0.5262 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 5.21e-06/0.4285, allocations: 4 kB / 0.6657 GB, free: 9.145 MB / 0.5262 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.001164/0.4296, allocations: 0.5627 MB / 0.6663 GB, free: 8.613 MB / 0.5262 GB Notification: Performance of postOpt tearingSystem (simulation): time 7.343e-06/0.4296, allocations: 8 kB / 0.6663 GB, free: 8.605 MB / 0.5262 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 9.57e-05/0.4297, allocations: 97.12 kB / 0.6664 GB, free: 8.512 MB / 0.5262 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 5.971e-06/0.4297, allocations: 8 kB / 0.6664 GB, free: 8.504 MB / 0.5262 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 1.563e-06/0.4297, allocations: 0 / 0.6664 GB, free: 8.504 MB / 0.5262 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.001757/0.4315, allocations: 3.893 MB / 0.6702 GB, free: 4.281 MB / 0.5262 GB Notification: Performance of postOpt removeConstants (simulation): time 0.000404/0.4319, allocations: 222.7 kB / 0.6704 GB, free: 4.062 MB / 0.5262 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0002155/0.4321, allocations: 127.6 kB / 0.6705 GB, free: 3.941 MB / 0.5262 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.0005492/0.4327, allocations: 99.94 kB / 0.6706 GB, free: 3.844 MB / 0.5262 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0002559/0.4329, allocations: 243.1 kB / 0.6708 GB, free: 3.609 MB / 0.5262 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 7.263e-05/0.433, allocations: 79.92 kB / 0.6709 GB, free: 3.535 MB / 0.5262 GB Notification: Performance of sorting global known variables: time 0.0002934/0.4333, allocations: 0.4977 MB / 0.6714 GB, free: 3.09 MB / 0.5262 GB Notification: Performance of sort global known variables: time 8e-08/0.4333, allocations: 0 / 0.6714 GB, free: 3.09 MB / 0.5262 GB Notification: Performance of remove unused functions: time 0.0009201/0.4342, allocations: 0.6523 MB / 0.672 GB, free: 2.438 MB / 0.5262 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC) * Number of discrete variables: 108 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising) * Number of discrete states: 96 (patient.periodicDose.pulse.count,patient.peripheral.Cmin,$whenCondition41,patient.peripheral.Cmax,$whenCondition40,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition39,patient.periodicDose.absorptionLumen.Cmax,$whenCondition38,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition37,patient.central.Cmax,$whenCondition36,patient.central.rising,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmin,$whenCondition34,patient_high.peripheral.Cmax,$whenCondition33,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition32,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition31,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition30,patient_high.central.Cmax,$whenCondition29,patient_high.central.rising,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmin,$whenCondition27,patient_low.peripheral.Cmax,$whenCondition26,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition25,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition24,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition23,patient_low.central.Cmax,$whenCondition22,patient_low.central.rising,ref.periodicDose.pulse.count,ref.peripheral.Cmin,$whenCondition20,ref.peripheral.Cmax,$whenCondition19,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition18,ref.periodicDose.absorptionLumen.Cmax,$whenCondition17,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition16,ref.central.Cmax,$whenCondition15,ref.central.rising,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmin,$whenCondition13,ref_high.peripheral.Cmax,$whenCondition12,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition11,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition10,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition9,ref_high.central.Cmax,$whenCondition8,ref_high.central.rising,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmin,$whenCondition6,ref_low.peripheral.Cmax,$whenCondition5,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition4,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition3,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition2,ref_low.central.Cmax,$whenCondition1,ref_low.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (228): * Single equations (assignments): 198 * Array equations: 0 * Algorithm blocks: 18 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0002262/0.4344, allocations: 319.8 kB / 0.6724 GB, free: 2.152 MB / 0.5262 GB Notification: Performance of simCode: created initialization part: time 0.00198/0.4364, allocations: 3.828 MB / 0.6761 GB, free: 13.87 MB / 0.5418 GB Notification: Performance of simCode: created event and clocks part: time 1.246e-05/0.4364, allocations: 13.62 kB / 0.6761 GB, free: 13.86 MB / 0.5418 GB Notification: Performance of simCode: created simulation system equations: time 0.001081/0.4375, allocations: 2.232 MB / 0.6783 GB, free: 11.31 MB / 0.5418 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.001661/0.4392, allocations: 0.7229 MB / 0.679 GB, free: 10.68 MB / 0.5418 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.005167/0.4443, allocations: 4.641 MB / 0.6835 GB, free: 5.953 MB / 0.5418 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.0003182/0.4447, allocations: 389.8 kB / 0.6839 GB, free: 5.547 MB / 0.5418 GB Notification: Performance of simCode: alias equations: time 0.0006873/0.4453, allocations: 241.8 kB / 0.6841 GB, free: 5.32 MB / 0.5418 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.001268/0.4466, allocations: 0.8082 MB / 0.6849 GB, free: 4.52 MB / 0.5418 GB Notification: Performance of SimCode: time 1.122e-06/0.4466, allocations: 0 / 0.6849 GB, free: 4.52 MB / 0.5418 GB Notification: Performance of Templates: time 0.04186/0.4885, allocations: 40.11 MB / 0.7241 GB, free: 15.06 MB / 0.5887 GB " [Timeout remaining time 660] make -j1 -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.sim & ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic -abortSlowSimulation -alarm=240 -s gbode -gbm=radauIIA3 -lv LOG_STATS > Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 5.761605950072408]