Environment - simulationEnvironment: startTime=0 stopTime=864000 tolerance=1e-09 numberOfIntervals=86400 stepSize=10 Regular simulation: ./Pharmacolibrary_Pharmacolibrary.Examples.PK_Lithium.PK_1C_Lithium_CI -abortSlowSimulation -alarm=240 -s gbode -gbm=radauIIA3 -lv LOG_STATS LOG_STDOUT | warning | Numerical Jacobians without coloring are currently not supported by GBODE. Colored numerical Jacobian will be used. LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 658.532387 | | | | ((pK_lower.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= pK_lower.periodicDose.absorptionLumen.M, has value: -2.38095e-11" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable] | | | | The following assertion has been violated at time 658.532387 | | | | ((pK_lower.periodicDose.variableDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= pK_lower.periodicDose.variableDose.TotalCumulativeMass, has value: -7.92363e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 658.532387 | | | | ((pK_1C_Lithium_upper.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= pK_1C_Lithium_upper.periodicDose.absorptionLumen.M, has value: -1.42857e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable] | | | | The following assertion has been violated at time 658.532387 | | | | ((pK_1C_Lithium_upper.periodicDose.variableDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= pK_1C_Lithium_upper.periodicDose.variableDose.TotalCumulativeMass, has value: -4.75418e-11" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 658.532387 | | | | ((pK_1C_Lithium.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= pK_1C_Lithium.periodicDose.absorptionLumen.M, has value: -9.52381e-11" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable] | | | | The following assertion has been violated at time 658.532387 | | | | ((pK_1C_Lithium.periodicDose.variableDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= pK_1C_Lithium.periodicDose.variableDose.TotalCumulativeMass, has value: -3.16945e-11" LOG_STATS | info | gbode (single-rate integration): radauIIA3 LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0s reading init.xml | | | | | | 0s reading info.xml | | | | | | 6.5844e-05s [ 0.0%] pre-initialization | | | | | | 6.8279e-05s [ 0.0%] initialization | | | | | | 0s [ 0.0%] steps | | | | | | 0s [ 0.0%] solver (excl. callbacks) | | | | | | 1.994e-06s [ 0.0%] creating output-file | | | | | | 0.000431977s [ 0.2%] event-handling | | | | | | 0s [ 0.0%] overhead | | | | | | 0.213386s [ 99.7%] simulation | | | | | | 0.213954s [100.0%] total | | | | | events | | | | | | 112 state events | | | | | | 40 time events | | | | | solver: gbode | | | | | | 1244 steps taken | | | | | | 5182 calls of functionODE | | | | | | 143 evaluations of jacobian | | | | | | 86 error test failures | | | | | | 0 convergence test failures | | | | | | 0s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.