Environment - simulationEnvironment: startTime=0 stopTime=86400 tolerance=1e-09 numberOfIntervals=86400 stepSize=1 Regular simulation: ./Pharmacolibrary_Pharmacolibrary.Pharmacokinetic.Models.PK_2C_enteral -abortSlowSimulation -alarm=240 -lv LOG_STATS LOG_STDOUT | warning | Numerical Jacobians without coloring are currently not supported by GBODE. Colored numerical Jacobian will be used. LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 29459.999996 | | | | ((periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= periodicDose.absorptionLumen.M, has value: -6.39372e-12" LOG_STATS | info | gbode (single-rate integration): radauIIA3 LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0.00113833s reading init.xml | | | | | | 0.000136587s reading info.xml | | | | | | 0.000129373s [ 0.2%] pre-initialization | | | | | | 3.9134e-05s [ 0.1%] initialization | | | | | | 1.6782e-05s [ 0.0%] steps | | | | | | 0s [ 0.0%] solver (excl. callbacks) | | | | | | 0s [ 0.0%] creating output-file | | | | | | 0.000970267s [ 1.8%] event-handling | | | | | | 0.00344596s [ 6.4%] overhead | | | | | | 0.0494265s [ 91.5%] simulation | | | | | | 0.0540281s [100.0%] total | | | | | events | | | | | | 26 state events | | | | | | 20 time events | | | | | solver: gbode | | | | | | 1035 steps taken | | | | | | 4505 calls of functionODE | | | | | | 40 evaluations of jacobian | | | | | | 96 error test failures | | | | | | 0 convergence test failures | | | | | | 1.3579e-05s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.