Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.001008/0.001008, allocations: 80.88 kB / 19.94 MB, free: 4.551 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.001107/0.001107, allocations: 177 kB / 23.36 MB, free: 1.133 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 0.9377/0.9377, allocations: 177.1 MB / 203.8 MB, free: 5.484 MB / 186.7 MB " [Timeout remaining time 179] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 1.578/1.578, allocations: 273.5 MB / 0.5212 GB, free: 14.7 MB / 458.7 MB " [Timeout remaining time 178] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") [Timeout 660] "Notification: Performance of FrontEnd - loaded program: time 1.633e-06/1.633e-06, allocations: 0 / 0.5954 GB, free: 2.777 MB / 0.5105 GB Notification: Performance of FrontEnd - Absyn->SCode: time 1.442e-05/1.605e-05, allocations: 5.547 kB / 0.5954 GB, free: 2.773 MB / 0.5105 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic): time 0.008833/0.008849, allocations: 13.08 MB / 0.6082 GB, free: 5.746 MB / 0.5261 GB Notification: Performance of NFInst.instExpressions: time 0.005059/0.01391, allocations: 2.793 MB / 0.6109 GB, free: 2.957 MB / 0.5261 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.0007584/0.01467, allocations: 19.94 kB / 0.6109 GB, free: 2.938 MB / 0.5261 GB Notification: Performance of NFTyping.typeComponents: time 0.0004873/0.01515, allocations: 308.9 kB / 0.6112 GB, free: 2.633 MB / 0.5261 GB Notification: Performance of NFTyping.typeBindings: time 0.001359/0.01651, allocations: 0.914 MB / 0.6121 GB, free: 1.711 MB / 0.5261 GB Notification: Performance of NFTyping.typeClassSections: time 0.0009594/0.01747, allocations: 0.6745 MB / 0.6128 GB, free: 1.039 MB / 0.5261 GB Notification: Performance of NFFlatten.flatten: time 0.361/0.3785, allocations: 3.261 MB / 0.6159 GB, free: 42.84 MB / 0.5262 GB Notification: Performance of NFFlatten.resolveConnections: time 0.0007063/0.3792, allocations: 483.9 kB / 0.6164 GB, free: 42.72 MB / 0.5262 GB Notification: Performance of NFEvalConstants.evaluate: time 0.001659/0.3808, allocations: 1.654 MB / 0.618 GB, free: 42.6 MB / 0.5262 GB Notification: Performance of NFSimplifyModel.simplify: time 0.001084/0.3819, allocations: 0.9366 MB / 0.6189 GB, free: 42.49 MB / 0.5262 GB Notification: Performance of NFPackage.collectConstants: time 0.0003375/0.3822, allocations: 282.9 kB / 0.6192 GB, free: 42.49 MB / 0.5262 GB Notification: Performance of NFFlatten.collectFunctions: time 0.0003906/0.3826, allocations: 284.6 kB / 0.6195 GB, free: 42.49 MB / 0.5262 GB Notification: Performance of NFScalarize.scalarize: time 0.0002987/0.3829, allocations: 0.5105 MB / 0.62 GB, free: 42.39 MB / 0.5262 GB Notification: Performance of NFVerifyModel.verify: time 0.0008158/0.3838, allocations: 0.9489 MB / 0.6209 GB, free: 42.29 MB / 0.5262 GB Notification: Performance of NFConvertDAE.convert: time 0.001426/0.3852, allocations: 1.905 MB / 0.6228 GB, free: 41.77 MB / 0.5262 GB Notification: Performance of FrontEnd - DAE generated: time 3.667e-06/0.3852, allocations: 2.375 kB / 0.6228 GB, free: 41.77 MB / 0.5262 GB Notification: Performance of FrontEnd: time 1.052e-06/0.3852, allocations: 0 / 0.6228 GB, free: 41.77 MB / 0.5262 GB Notification: Performance of Transformations before backend: time 1.449e-05/0.3852, allocations: 1.281 kB / 0.6228 GB, free: 41.77 MB / 0.5262 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 402 * Number of variables: 402 Notification: Performance of Generate backend data structure: time 0.002646/0.3878, allocations: 3.095 MB / 0.6258 GB, free: 39.64 MB / 0.5262 GB Notification: Performance of prepare preOptimizeDAE: time 3.342e-05/0.3879, allocations: 9.438 kB / 0.6258 GB, free: 39.64 MB / 0.5262 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.0003203/0.3882, allocations: 285.1 kB / 0.6261 GB, free: 39.6 MB / 0.5262 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.0008411/0.389, allocations: 0.6636 MB / 0.6267 GB, free: 39.21 MB / 0.5262 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 8.402e-05/0.3891, allocations: 118.1 kB / 0.6268 GB, free: 39.16 MB / 0.5262 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.0002068/0.3893, allocations: 199.4 kB / 0.627 GB, free: 39.1 MB / 0.5262 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.001584/0.3909, allocations: 1.715 MB / 0.6287 GB, free: 38.17 MB / 0.5262 GB Notification: Performance of preOpt findStateOrder (simulation): time 6.294e-05/0.391, allocations: 28.02 kB / 0.6287 GB, free: 38.16 MB / 0.5262 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 9.67e-05/0.3911, allocations: 69.19 kB / 0.6288 GB, free: 38.11 MB / 0.5262 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 3.004e-05/0.3911, allocations: 36.5 kB / 0.6288 GB, free: 38.11 MB / 0.5262 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.0009686/0.3921, allocations: 1.191 MB / 0.63 GB, free: 37.41 MB / 0.5262 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.003904/0.396, allocations: 3.592 MB / 0.6335 GB, free: 35.12 MB / 0.5262 GB Notification: Performance of preOpt comSubExp (simulation): time 0.001021/0.397, allocations: 1.256 MB / 0.6347 GB, free: 34.26 MB / 0.5262 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.000498/0.3975, allocations: 0.8266 MB / 0.6355 GB, free: 33.56 MB / 0.5262 GB Notification: Performance of preOpt evalFunc (simulation): time 7.272e-05/0.3976, allocations: 43.16 kB / 0.6356 GB, free: 33.55 MB / 0.5262 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.001199/0.3988, allocations: 2.559 MB / 0.6381 GB, free: 31.23 MB / 0.5262 GB Notification: Performance of pre-optimization done (n=264): time 3.987e-06/0.3988, allocations: 1.188 kB / 0.6381 GB, free: 31.23 MB / 0.5262 GB Notification: Performance of matching and sorting (n=282): time 0.005096/0.4039, allocations: 6.439 MB / 0.6444 GB, free: 26.52 MB / 0.5262 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.0002319/0.4041, allocations: 1.653 MB / 0.646 GB, free: 24.56 MB / 0.5262 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.0007317/0.4048, allocations: 1.005 MB / 0.6469 GB, free: 24.18 MB / 0.5262 GB Notification: Performance of collectPreVariables (initialization): time 0.0001189/0.4049, allocations: 116.9 kB / 0.6471 GB, free: 24.1 MB / 0.5262 GB Notification: Performance of collectInitialEqns (initialization): time 0.0002256/0.4052, allocations: 0.506 MB / 0.6476 GB, free: 23.73 MB / 0.5262 GB Notification: Performance of collectInitialBindings (initialization): time 0.0004111/0.4056, allocations: 0.9188 MB / 0.6485 GB, free: 23.01 MB / 0.5262 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0004708/0.4061, allocations: 492.8 kB / 0.6489 GB, free: 22.81 MB / 0.5262 GB Notification: Performance of setup shared object (initialization): time 2.453e-05/0.4061, allocations: 306.6 kB / 0.6492 GB, free: 22.51 MB / 0.5262 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.0006315/0.4067, allocations: 1.064 MB / 0.6503 GB, free: 21.62 MB / 0.5262 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.006811/0.4135, allocations: 1.846 MB / 0.6521 GB, free: 19.72 MB / 0.5262 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.001932/0.4155, allocations: 3.764 MB / 0.6557 GB, free: 16.44 MB / 0.5262 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 1.297e-05/0.4155, allocations: 5.5 kB / 0.6557 GB, free: 16.44 MB / 0.5262 GB Notification: Performance of matching and sorting (n=426) (initialization): time 0.007899/0.4234, allocations: 2.798 MB / 0.6585 GB, free: 14.5 MB / 0.5262 GB Notification: Performance of prepare postOptimizeDAE: time 0.0001265/0.4235, allocations: 0.6768 MB / 0.6591 GB, free: 13.71 MB / 0.5262 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 2.237e-05/0.4235, allocations: 20.41 kB / 0.6591 GB, free: 13.71 MB / 0.5262 GB Notification: Performance of postOpt tearingSystem (initialization): time 3.647e-05/0.4236, allocations: 37.97 kB / 0.6592 GB, free: 13.71 MB / 0.5262 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.007435/0.431, allocations: 0.6619 MB / 0.6598 GB, free: 13.6 MB / 0.5262 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 3.326e-05/0.431, allocations: 54.02 kB / 0.6599 GB, free: 13.6 MB / 0.5262 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.0008687/0.4319, allocations: 144.5 kB / 0.66 GB, free: 13.53 MB / 0.5262 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.00012/0.432, allocations: 106.8 kB / 0.6601 GB, free: 13.5 MB / 0.5262 GB Warning: Assuming fixed start value for the following 84 variables: ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 174 ($PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (402): * Single equations (assignments): 378 * Array equations: 0 * Algorithm blocks: 24 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.0007899/0.4328, allocations: 1.25 MB / 0.6613 GB, free: 12.52 MB / 0.5262 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0002605/0.4331, allocations: 263.9 kB / 0.6616 GB, free: 12.43 MB / 0.5262 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.000186/0.4332, allocations: 207.7 kB / 0.6618 GB, free: 12.27 MB / 0.5262 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 1.248e-05/0.4333, allocations: 21.03 kB / 0.6618 GB, free: 12.27 MB / 0.5262 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 1.553e-05/0.4333, allocations: 3.469 kB / 0.6618 GB, free: 12.27 MB / 0.5262 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 1.519e-05/0.4333, allocations: 11.95 kB / 0.6618 GB, free: 12.26 MB / 0.5262 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.008949/0.4422, allocations: 3.744 MB / 0.6655 GB, free: 9.59 MB / 0.5262 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 5.861e-06/0.4422, allocations: 0 / 0.6655 GB, free: 9.59 MB / 0.5262 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.004224/0.4465, allocations: 427.2 kB / 0.6659 GB, free: 9.191 MB / 0.5262 GB Notification: Performance of postOpt tearingSystem (simulation): time 1.015e-05/0.4465, allocations: 8 kB / 0.6659 GB, free: 9.184 MB / 0.5262 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0001161/0.4466, allocations: 91.89 kB / 0.666 GB, free: 9.098 MB / 0.5262 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 9.358e-06/0.4466, allocations: 16.73 kB / 0.666 GB, free: 9.086 MB / 0.5262 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 2.194e-06/0.4466, allocations: 0 / 0.666 GB, free: 9.086 MB / 0.5262 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.002221/0.4488, allocations: 3.89 MB / 0.6698 GB, free: 4.863 MB / 0.5262 GB Notification: Performance of postOpt removeConstants (simulation): time 0.003516/0.4523, allocations: 227.9 kB / 0.67 GB, free: 4.641 MB / 0.5262 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0002759/0.4526, allocations: 116 kB / 0.6701 GB, free: 4.527 MB / 0.5262 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.000754/0.4534, allocations: 101.2 kB / 0.6702 GB, free: 4.43 MB / 0.5262 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0003132/0.4537, allocations: 244.2 kB / 0.6705 GB, free: 4.195 MB / 0.5262 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 9.296e-05/0.4538, allocations: 79.95 kB / 0.6705 GB, free: 4.117 MB / 0.5262 GB Notification: Performance of sorting global known variables: time 0.0003697/0.4541, allocations: 0.4975 MB / 0.671 GB, free: 3.672 MB / 0.5262 GB Notification: Performance of sort global known variables: time 7e-08/0.4541, allocations: 0 / 0.671 GB, free: 3.672 MB / 0.5262 GB Notification: Performance of remove unused functions: time 0.004333/0.4585, allocations: 0.6536 MB / 0.6717 GB, free: 3.02 MB / 0.5262 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC) * Number of discrete variables: 108 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising) * Number of discrete states: 96 (patient.periodicDose.pulse.count,patient.peripheral.Cmin,$whenCondition41,patient.peripheral.Cmax,$whenCondition40,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition39,patient.periodicDose.absorptionLumen.Cmax,$whenCondition38,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition37,patient.central.Cmax,$whenCondition36,patient.central.rising,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmin,$whenCondition34,patient_high.peripheral.Cmax,$whenCondition33,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition32,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition31,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition30,patient_high.central.Cmax,$whenCondition29,patient_high.central.rising,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmin,$whenCondition27,patient_low.peripheral.Cmax,$whenCondition26,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition25,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition24,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition23,patient_low.central.Cmax,$whenCondition22,patient_low.central.rising,ref.periodicDose.pulse.count,ref.peripheral.Cmin,$whenCondition20,ref.peripheral.Cmax,$whenCondition19,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition18,ref.periodicDose.absorptionLumen.Cmax,$whenCondition17,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition16,ref.central.Cmax,$whenCondition15,ref.central.rising,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmin,$whenCondition13,ref_high.peripheral.Cmax,$whenCondition12,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition11,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition10,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition9,ref_high.central.Cmax,$whenCondition8,ref_high.central.rising,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmin,$whenCondition6,ref_low.peripheral.Cmax,$whenCondition5,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition4,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition3,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition2,ref_low.central.Cmax,$whenCondition1,ref_low.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (228): * Single equations (assignments): 198 * Array equations: 0 * Algorithm blocks: 18 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0002878/0.4588, allocations: 321.5 kB / 0.672 GB, free: 2.73 MB / 0.5262 GB Notification: Performance of simCode: created initialization part: time 0.005151/0.4639, allocations: 3.832 MB / 0.6757 GB, free: 14.45 MB / 0.5418 GB Notification: Performance of simCode: created event and clocks part: time 1.663e-05/0.4639, allocations: 12 kB / 0.6757 GB, free: 14.44 MB / 0.5418 GB Notification: Performance of simCode: created simulation system equations: time 0.001401/0.4653, allocations: 2.23 MB / 0.6779 GB, free: 11.89 MB / 0.5418 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.005306/0.4706, allocations: 0.7048 MB / 0.6786 GB, free: 11.28 MB / 0.5418 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.005362/0.476, allocations: 4.647 MB / 0.6831 GB, free: 6.566 MB / 0.5418 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.0002665/0.4763, allocations: 389.6 kB / 0.6835 GB, free: 6.16 MB / 0.5418 GB Notification: Performance of simCode: alias equations: time 0.0005547/0.4768, allocations: 240.7 kB / 0.6837 GB, free: 5.934 MB / 0.5418 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.001319/0.4781, allocations: 0.789 MB / 0.6845 GB, free: 5.152 MB / 0.5418 GB Notification: Performance of SimCode: time 1.172e-06/0.4781, allocations: 0 / 0.6845 GB, free: 5.152 MB / 0.5418 GB Notification: Performance of Templates: time 0.03908/0.5172, allocations: 39.16 MB / 0.7227 GB, free: 0.5703 MB / 0.573 GB " [Timeout remaining time 659] make -j1 -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.sim & ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic -abortSlowSimulation -alarm=240 -lv LOG_STATS > Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 5.43427277635783]