startTime=0 stopTime=86400 tolerance=1e-06 numberOfIntervals=86400 stepSize=1 wasm-jit simulation: simulate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic,startTime=0,stopTime=86400,tolerance=1e-06,numberOfIntervals=86400,outputFormat="empty",variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic",simflags="-abortSlowSimulation -alarm=240 -lv LOG_STATS") LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((patient_high.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_high.periodicDose.absorptionLumen.M, has value: -2.17315e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((patient_low.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_low.periodicDose.absorptionLumen.M, has value: -2.17315e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((patient.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient.periodicDose.absorptionLumen.M, has value: -2.17315e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((ref_high.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= ref_high.periodicDose.absorptionLumen.M, has value: -2.17315e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((ref_low.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= ref_low.periodicDose.absorptionLumen.M, has value: -2.17315e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((ref.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= ref.periodicDose.absorptionLumen.M, has value: -2.17315e-12" LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0s reading init.xml | | | | | | 0s reading info.xml | | | | | | 2.5818e-05s [ 0.0%] pre-initialization | | | | | | 0.000102503s [ 0.0%] initialization | | | | | | 0s [ 0.0%] steps | | | | | | 0.0933007s [ 8.9%] solver (excl. callbacks) | | | | | | 0.0175725s [ 1.7%] creating output-file | | | | | | 0.394609s [ 37.5%] event-handling | | | | | | 0s [ 0.0%] overhead | | | | | | 0.546635s [ 51.9%] simulation | | | | | | 1.05224s [100.0%] total | | | | | events | | | | | | 75 state events | | | | | | 6 time events | | | | | solver: dassl | | | | | | 1449 steps taken | | | | | | 1702 calls of functionODE | | | | | | 1056 evaluations of jacobian | | | | | | 22 error test failures | | | | | | 0 convergence test failures | | | | | | 0.013621s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.