startTime=0 stopTime=864000 tolerance=1e-06 numberOfIntervals=86400 stepSize=10 wasm-jit simulation: simulate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment,startTime=0,stopTime=864000,tolerance=1e-06,numberOfIntervals=86400,outputFormat="empty",variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment",simflags="-abortSlowSimulation -alarm=240 -lv LOG_STATS") LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient4.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient4.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient_citalopram_CYP2C19_2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_CYP2C19_2.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient2.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient_citalopram_normal.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_normal.dose.absorptionLumen.M, has value: -1e-10" LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0s reading init.xml | | | | | | 0s reading info.xml | | | | | | 4.1047e-05s [ 0.0%] pre-initialization | | | | | | 9.6472e-05s [ 0.0%] initialization | | | | | | 0s [ 0.0%] steps | | | | | | 0.038232s [ 6.9%] solver (excl. callbacks) | | | | | | 0.0114069s [ 2.1%] creating output-file | | | | | | 0.210058s [ 37.9%] event-handling | | | | | | 0s [ 0.0%] overhead | | | | | | 0.294009s [ 53.1%] simulation | | | | | | 0.553844s [100.0%] total | | | | | events | | | | | | 111 state events | | | | | | 0 time events | | | | | solver: dassl | | | | | | 1346 steps taken | | | | | | 1714 calls of functionODE | | | | | | 1031 evaluations of jacobian | | | | | | 55 error test failures | | | | | | 0 convergence test failures | | | | | | 0.00449532s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.