startTime=0 stopTime=86400 tolerance=1e-06 numberOfIntervals=86400 stepSize=1 wasm-jit simulation: simulate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic,startTime=0,stopTime=86400,tolerance=1e-06,numberOfIntervals=86400,outputFormat="empty",variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic",simflags="-abortSlowSimulation -alarm=240 -lv LOG_STATS") LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((patient_high.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_high.periodicDose.absorptionLumen.M, has value: -1.76475e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((patient_low.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_low.periodicDose.absorptionLumen.M, has value: -1.76475e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((patient.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient.periodicDose.absorptionLumen.M, has value: -1.76475e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((ref_high.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= ref_high.periodicDose.absorptionLumen.M, has value: -1.76475e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((ref_low.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= ref_low.periodicDose.absorptionLumen.M, has value: -1.76475e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((ref.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= ref.periodicDose.absorptionLumen.M, has value: -1.76475e-12" LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0s reading init.xml | | | | | | 0s reading info.xml | | | | | | 2.9375e-05s [ 0.0%] pre-initialization | | | | | | 7.1936e-05s [ 0.0%] initialization | | | | | | 0s [ 0.0%] steps | | | | | | 0.0872464s [ 8.7%] solver (excl. callbacks) | | | | | | 0.0172322s [ 1.7%] creating output-file | | | | | | 0.368929s [ 36.8%] event-handling | | | | | | 0s [ 0.0%] overhead | | | | | | 0.528543s [ 52.7%] simulation | | | | | | 1.00205s [100.0%] total | | | | | events | | | | | | 86 state events | | | | | | 0 time events | | | | | solver: dassl | | | | | | 1471 steps taken | | | | | | 1726 calls of functionODE | | | | | | 1077 evaluations of jacobian | | | | | | 21 error test failures | | | | | | 0 convergence test failures | | | | | | 0.0120603s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.