Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "[:1:22-1:33:writable] Warning: Modelica only supports 32-bit signed integers! Transforming: 13743895347 into a real Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.0002444/0.0002444, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.000185/0.000185, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 0.1349/0.1349, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Drugs/ATC/B/B02BD15.mo:9:22-9:32:writable] Warning: Modelica only supports 32-bit signed integers! Transforming: 6000000000 into a real [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 0.5856/0.5856, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 179] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: simulate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic,startTime=0,stopTime=86400,tolerance=1e-06,numberOfIntervals=86400,outputFormat="empty",variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic",simflags="-abortSlowSimulation -alarm=240 -lv LOG_STATS") simulate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic,startTime=0,stopTime=86400,tolerance=1e-06,numberOfIntervals=86400,outputFormat="empty",variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic",simflags="-abortSlowSimulation -alarm=240 -lv LOG_STATS") [Timeout 900] "Notification: Performance of FrontEnd - loaded program: time 1.313e-06/1.313e-06, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FrontEnd - Absyn->SCode: time 2.867e-05/2.999e-05, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic): time 0.01604/0.01607, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFInst.instExpressions: time 0.008067/0.02414, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFInst.updateImplicitVariability: time 0.001112/0.02525, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFTyping.typeComponents: time 0.001596/0.02685, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFTyping.typeBindings: time 0.00308/0.02993, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFTyping.typeClassSections: time 0.001585/0.03151, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFFlatten.flatten: time 0.002584/0.0341, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFFlatten.resolveConnections: time 0.0008883/0.03498, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFEvalConstants.evaluate: time 0.002202/0.03719, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFSimplifyModel.simplify: time 0.001273/0.03846, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFPackage.collectConstants: time 0.0002832/0.03874, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFFlatten.collectFunctions: time 0.0005072/0.03925, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFScalarize.scalarize: time 0.0005988/0.03985, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFVerifyModel.verify: time 0.001039/0.04089, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFConvertDAE.convert: time 0.003434/0.04432, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FrontEnd - DAE generated: time 0.0003737/0.0447, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FrontEnd: time 2.845e-06/0.0447, allocations: 0 / 0, free: 0 / 0 Notification: Performance of Transformations before backend: time 2.141e-05/0.04472, allocations: 0 / 0, free: 0 / 0 Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 486 * Number of variables: 486 Notification: Performance of Generate backend data structure: time 0.003708/0.04843, allocations: 0 / 0, free: 0 / 0 Notification: Performance of prepare preOptimizeDAE: time 0.000172/0.0486, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt normalInlineFunction (simulation): time 0.001079/0.04968, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt evaluateParameters (simulation): time 0.001357/0.05104, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt simplifyIfEquations (simulation): time 0.0001804/0.05122, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt expandDerOperator (simulation): time 0.000315/0.05153, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt clockPartitioning (simulation): time 0.00224/0.05377, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt findStateOrder (simulation): time 7.485e-05/0.05385, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt replaceEdgeChange (simulation): time 0.0001604/0.05401, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt inlineArrayEqn (simulation): time 4.184e-05/0.05405, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt removeEqualRHS (simulation): time 0.001282/0.05533, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.00556/0.06089, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt comSubExp (simulation): time 0.001254/0.06214, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt resolveLoops (simulation): time 0.0005852/0.06273, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt evalFunc (simulation): time 5.797e-05/0.06279, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.00154/0.06433, allocations: 0 / 0, free: 0 / 0 Notification: Performance of pre-optimization done (n=300): time 1.442e-05/0.06434, allocations: 0 / 0, free: 0 / 0 Notification: Performance of matching and sorting (n=318): time 0.007802/0.07214, allocations: 0 / 0, free: 0 / 0 Notification: Performance of inlineWhenForInitialization (initialization): time 0.0002324/0.07238, allocations: 0 / 0, free: 0 / 0 Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.001329/0.07371, allocations: 0 / 0, free: 0 / 0 Notification: Performance of collectPreVariables (initialization): time 0.0002779/0.07398, allocations: 0 / 0, free: 0 / 0 Notification: Performance of collectInitialEqns (initialization): time 0.0004088/0.07439, allocations: 0 / 0, free: 0 / 0 Notification: Performance of collectInitialBindings (initialization): time 0.0006677/0.07506, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simplifyInitialFunctions (initialization): time 0.0006041/0.07566, allocations: 0 / 0, free: 0 / 0 Notification: Performance of setup shared object (initialization): time 1.129e-05/0.07568, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preBalanceInitialSystem (initialization): time 0.000741/0.07642, allocations: 0 / 0, free: 0 / 0 Notification: Performance of partitionIndependentBlocks (initialization): time 0.0008873/0.0773, allocations: 0 / 0, free: 0 / 0 Notification: Performance of analyzeInitialSystem (initialization): time 0.002342/0.07965, allocations: 0 / 0, free: 0 / 0 Notification: Performance of solveInitialSystemEqSystem (initialization): time 3.001e-05/0.07968, allocations: 0 / 0, free: 0 / 0 Notification: Performance of matching and sorting (n=462) (initialization): time 0.002725/0.0824, allocations: 0 / 0, free: 0 / 0 Notification: Performance of prepare postOptimizeDAE: time 0.0001893/0.08259, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyComplexFunction (initialization): time 3.357e-05/0.08262, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt tearingSystem (initialization): time 5.332e-05/0.08268, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.001522/0.0842, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 7.46e-05/0.08427, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.001052/0.08532, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.0002975/0.08562, allocations: 0 / 0, free: 0 / 0 Warning: Assuming fixed start value for the following 84 variables: patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 186 ($PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.CYP2C19.status,patient_high.SLC22A2.status,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.CYP2C19.status,patient_low.SLC22A2.status,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.CYP2C19.status,patient.SLC22A2.status,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.CYP2C19.status,ref_high.SLC22A2.status,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.CYP2C19.status,ref_low.SLC22A2.status,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.CYP2C19.status,ref.SLC22A2.status,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (426): * Single equations (assignments): 390 * Array equations: 0 * Algorithm blocks: 36 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.00116/0.08678, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0006718/0.08745, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.000355/0.08781, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt inlineArrayEqn (simulation): time 2.328e-05/0.08783, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt constantLinearSystem (simulation): time 9.588e-06/0.08784, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifysemiLinear (simulation): time 2.047e-05/0.08786, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.004759/0.09262, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyComplexFunction (simulation): time 1.334e-05/0.09263, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.001137/0.09377, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt tearingSystem (simulation): time 1.71e-05/0.09379, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0001876/0.09398, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 2.567e-05/0.094, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 3.026e-06/0.094, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt symbolicJacobian (simulation): time 0.003669/0.09767, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt removeConstants (simulation): time 0.0008321/0.09851, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0008206/0.09933, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.0009243/0.1003, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0006096/0.1009, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt collapseArrayExpressions (simulation): time 0.0002839/0.1011, allocations: 0 / 0, free: 0 / 0 Notification: Performance of sorting global known variables: time 0.0006499/0.1018, allocations: 0 / 0, free: 0 / 0 Notification: Performance of sort global known variables: time 5.676e-05/0.1019, allocations: 0 / 0, free: 0 / 0 Notification: Performance of remove unused functions: time 0.002313/0.1042, allocations: 0 / 0, free: 0 / 0 Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC) * Number of discrete variables: 120 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,patient_high.SLC22A2.status,patient_high.CYP2C19.status,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,patient_low.SLC22A2.status,patient_low.CYP2C19.status,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising,patient.SLC22A2.status,patient.CYP2C19.status,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,ref_high.SLC22A2.status,ref_high.CYP2C19.status,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,ref_low.SLC22A2.status,ref_low.CYP2C19.status,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,ref.SLC22A2.status,ref.CYP2C19.status) * Number of discrete states: 108 (ref.periodicDose.pulse.count,ref.CYP2C19.status,ref.SLC22A2.status,ref.peripheral.Cmin,$whenCondition41,ref.peripheral.Cmax,$whenCondition40,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition39,ref.periodicDose.absorptionLumen.Cmax,$whenCondition38,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition37,ref.central.Cmax,$whenCondition36,ref.central.rising,ref_low.periodicDose.pulse.count,ref_low.CYP2C19.status,ref_low.SLC22A2.status,ref_low.peripheral.Cmin,$whenCondition34,ref_low.peripheral.Cmax,$whenCondition33,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition32,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition31,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition30,ref_low.central.Cmax,$whenCondition29,ref_low.central.rising,ref_high.periodicDose.pulse.count,ref_high.CYP2C19.status,ref_high.SLC22A2.status,ref_high.peripheral.Cmin,$whenCondition27,ref_high.peripheral.Cmax,$whenCondition26,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition25,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition24,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition23,ref_high.central.Cmax,$whenCondition22,ref_high.central.rising,patient.periodicDose.pulse.count,patient.CYP2C19.status,patient.SLC22A2.status,patient.peripheral.Cmin,$whenCondition20,patient.peripheral.Cmax,$whenCondition19,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition18,patient.periodicDose.absorptionLumen.Cmax,$whenCondition17,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition16,patient.central.Cmax,$whenCondition15,patient.central.rising,patient_low.periodicDose.pulse.count,patient_low.CYP2C19.status,patient_low.SLC22A2.status,patient_low.peripheral.Cmin,$whenCondition13,patient_low.peripheral.Cmax,$whenCondition12,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition11,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition10,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition9,patient_low.central.Cmax,$whenCondition8,patient_low.central.rising,patient_high.periodicDose.pulse.count,patient_high.CYP2C19.status,patient_high.SLC22A2.status,patient_high.peripheral.Cmin,$whenCondition6,patient_high.peripheral.Cmax,$whenCondition5,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition4,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition3,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition2,patient_high.central.Cmax,$whenCondition1,patient_high.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (252): * Single equations (assignments): 210 * Array equations: 0 * Algorithm blocks: 30 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0008006/0.105, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created initialization part: time 0.002515/0.1075, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created event and clocks part: time 2.154e-06/0.1075, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created simulation system equations: time 0.001316/0.1088, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.003744/0.1125, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.006214/0.1188, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: some other stuff during SimCode phase: time 0.000704/0.1195, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: alias equations: time 0.0007136/0.1202, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: all other stuff during SimCode phase: time 0.001741/0.1219, allocations: 0 / 0, free: 0 / 0 Notification: Performance of SimCode: time 8.821e-05/0.122, allocations: 0 / 0, free: 0 / 0 Notification: Performance of Templates: time 0.006855/0.1289, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 899] [Calling sys.exit(0), Time elapsed: 2.5025348463095725]