Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.001064/0.001064, allocations: 81.86 kB / 19.87 MB, free: 4.621 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.001073/0.001073, allocations: 169.7 kB / 23.27 MB, free: 1.219 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 0.9542/0.9542, allocations: 177.1 MB / 203.7 MB, free: 5.492 MB / 186.7 MB " [Timeout remaining time 179] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 1.574/1.574, allocations: 273.5 MB / 0.5212 GB, free: 14.68 MB / 458.7 MB " [Timeout remaining time 178] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body,tolerance=1e-06,outputFormat="empty",numberOfIntervals=499,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body") translateModel(Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body,tolerance=1e-06,outputFormat="empty",numberOfIntervals=499,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body") [Timeout 660] "Notification: Performance of FrontEnd - loaded program: time 1.563e-06/1.563e-06, allocations: 0 / 0.6475 GB, free: 38.43 MB / 0.5262 GB Notification: Performance of FrontEnd - Absyn->SCode: time 2.094e-05/2.25e-05, allocations: 6.25 kB / 0.6475 GB, free: 38.42 MB / 0.5262 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body): time 0.007542/0.007565, allocations: 11.54 MB / 0.6588 GB, free: 30.75 MB / 0.5262 GB Notification: Performance of NFInst.instExpressions: time 0.003111/0.01068, allocations: 2.486 MB / 0.6612 GB, free: 29.01 MB / 0.5262 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.0005568/0.01123, allocations: 22.75 kB / 0.6612 GB, free: 29.01 MB / 0.5262 GB Notification: Performance of NFTyping.typeComponents: time 0.0004193/0.01165, allocations: 299.9 kB / 0.6615 GB, free: 28.84 MB / 0.5262 GB Notification: Performance of NFTyping.typeBindings: time 0.0009501/0.0126, allocations: 0.7849 MB / 0.6623 GB, free: 28.27 MB / 0.5262 GB Notification: Performance of NFTyping.typeClassSections: time 0.0007515/0.01335, allocations: 0.5902 MB / 0.6628 GB, free: 27.92 MB / 0.5262 GB Notification: Performance of NFFlatten.flatten: time 0.001559/0.01491, allocations: 2.87 MB / 0.6656 GB, free: 26.38 MB / 0.5262 GB Notification: Performance of NFFlatten.resolveConnections: time 0.002017/0.01693, allocations: 3.228 MB / 0.6688 GB, free: 24.45 MB / 0.5262 GB Notification: Performance of NFEvalConstants.evaluate: time 0.001845/0.01877, allocations: 2.562 MB / 0.6713 GB, free: 23.39 MB / 0.5262 GB Notification: Performance of NFSimplifyModel.simplify: time 0.002144/0.02092, allocations: 1.98 MB / 0.6732 GB, free: 22.86 MB / 0.5262 GB Notification: Performance of NFPackage.collectConstants: time 0.0004409/0.02136, allocations: 423.3 kB / 0.6736 GB, free: 22.86 MB / 0.5262 GB Notification: Performance of NFFlatten.collectFunctions: time 0.0004773/0.02184, allocations: 425.7 kB / 0.674 GB, free: 22.86 MB / 0.5262 GB Notification: Performance of NFScalarize.scalarize: time 0.0005087/0.02235, allocations: 0.9244 MB / 0.6749 GB, free: 22.27 MB / 0.5262 GB Notification: Performance of NFVerifyModel.verify: time 0.0009835/0.02333, allocations: 1.294 MB / 0.6762 GB, free: 21.65 MB / 0.5262 GB Notification: Performance of NFConvertDAE.convert: time 0.002057/0.02539, allocations: 2.598 MB / 0.6787 GB, free: 20.38 MB / 0.5262 GB Notification: Performance of FrontEnd - DAE generated: time 3.857e-06/0.02539, allocations: 1.344 kB / 0.6787 GB, free: 20.38 MB / 0.5262 GB Notification: Performance of FrontEnd: time 1.012e-06/0.02539, allocations: 0 / 0.6787 GB, free: 20.38 MB / 0.5262 GB Notification: Performance of Transformations before backend: time 1.909e-05/0.02541, allocations: 0 / 0.6787 GB, free: 20.38 MB / 0.5262 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 449 * Number of variables: 449 Notification: Performance of Generate backend data structure: time 0.003426/0.02884, allocations: 2.913 MB / 0.6816 GB, free: 18.23 MB / 0.5262 GB Notification: Performance of prepare preOptimizeDAE: time 3.676e-05/0.02887, allocations: 9.906 kB / 0.6816 GB, free: 18.23 MB / 0.5262 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.0005489/0.02942, allocations: 377.9 kB / 0.682 GB, free: 18.05 MB / 0.5262 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.001002/0.03042, allocations: 1.07 MB / 0.683 GB, free: 17.18 MB / 0.5262 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 8.352e-05/0.03051, allocations: 134.1 kB / 0.6831 GB, free: 17.12 MB / 0.5262 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.0003131/0.03082, allocations: 215.9 kB / 0.6833 GB, free: 17.04 MB / 0.5262 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.002467/0.03329, allocations: 2.803 MB / 0.6861 GB, free: 15.23 MB / 0.5262 GB Notification: Performance of preOpt findStateOrder (simulation): time 4.356e-05/0.03333, allocations: 12 kB / 0.6861 GB, free: 15.22 MB / 0.5262 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 0.0002045/0.03354, allocations: 77.75 kB / 0.6862 GB, free: 15.16 MB / 0.5262 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 3.028e-05/0.03357, allocations: 42.31 kB / 0.6862 GB, free: 15.16 MB / 0.5262 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.002802/0.03637, allocations: 1.687 MB / 0.6878 GB, free: 14.57 MB / 0.5262 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.00976/0.04613, allocations: 6.955 MB / 0.6946 GB, free: 8.543 MB / 0.5262 GB Notification: Performance of preOpt comSubExp (simulation): time 0.001103/0.04723, allocations: 0.9733 MB / 0.6956 GB, free: 7.543 MB / 0.5262 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.000665/0.0479, allocations: 0.6522 MB / 0.6962 GB, free: 6.863 MB / 0.5262 GB Notification: Performance of preOpt evalFunc (simulation): time 7.757e-05/0.04797, allocations: 44.94 kB / 0.6963 GB, free: 6.828 MB / 0.5262 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.001109/0.04908, allocations: 1.494 MB / 0.6977 GB, free: 5.238 MB / 0.5262 GB Notification: Performance of preOpt simplifyInStream (simulation): time 0.003663/0.05275, allocations: 1.859 MB / 0.6995 GB, free: 3.422 MB / 0.5262 GB Notification: Performance of pre-optimization done (n=198): time 9.408e-06/0.05276, allocations: 0 / 0.6995 GB, free: 3.422 MB / 0.5262 GB Notification: Performance of matching and sorting (n=202): time 0.006023/0.05878, allocations: 4.809 MB / 0.7042 GB, free: 14.48 MB / 0.5418 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.0001318/0.05891, allocations: 409.8 kB / 0.7046 GB, free: 13.99 MB / 0.5418 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.0005901/0.0595, allocations: 0.8457 MB / 0.7055 GB, free: 13.12 MB / 0.5418 GB Notification: Performance of collectPreVariables (initialization): time 0.0001495/0.05965, allocations: 65.7 kB / 0.7055 GB, free: 13.05 MB / 0.5418 GB Notification: Performance of collectInitialEqns (initialization): time 0.0004013/0.06005, allocations: 0.7545 MB / 0.7063 GB, free: 12.29 MB / 0.5418 GB Notification: Performance of collectInitialBindings (initialization): time 0.0004591/0.06051, allocations: 0.7398 MB / 0.707 GB, free: 11.54 MB / 0.5418 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0006619/0.06117, allocations: 0.5992 MB / 0.7076 GB, free: 10.93 MB / 0.5418 GB Notification: Performance of setup shared object (initialization): time 0.0001002/0.06127, allocations: 476.8 kB / 0.708 GB, free: 10.46 MB / 0.5418 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.0009089/0.06218, allocations: 0.8744 MB / 0.7089 GB, free: 9.527 MB / 0.5418 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.001156/0.06334, allocations: 1.538 MB / 0.7104 GB, free: 7.641 MB / 0.5418 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.002888/0.06622, allocations: 3.061 MB / 0.7134 GB, free: 4.215 MB / 0.5418 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 9.938e-06/0.06623, allocations: 4 kB / 0.7134 GB, free: 4.211 MB / 0.5418 GB Notification: Performance of matching and sorting (n=298) (initialization): time 0.002942/0.06918, allocations: 2.802 MB / 0.7161 GB, free: 1.289 MB / 0.5418 GB Notification: Performance of prepare postOptimizeDAE: time 0.0001112/0.06929, allocations: 271.2 kB / 0.7164 GB, free: 0.9688 MB / 0.5418 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 1.531e-05/0.0693, allocations: 12 kB / 0.7164 GB, free: 0.957 MB / 0.5418 GB Notification: Performance of postOpt tearingSystem (initialization): time 2.79e-05/0.06933, allocations: 23.94 kB / 0.7164 GB, free: 0.9336 MB / 0.5418 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.001747/0.07108, allocations: 0.8348 MB / 0.7172 GB, free: 100 kB / 0.5418 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 2.913e-05/0.07111, allocations: 31.92 kB / 0.7172 GB, free: 68 kB / 0.5418 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.001099/0.07221, allocations: 100 kB / 0.7173 GB, free: 15.96 MB / 0.5574 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.0002034/0.07241, allocations: 191.7 kB / 0.7175 GB, free: 15.78 MB / 0.5574 GB Warning: Assuming fixed start value for the following 42 variables: venous.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real lungs.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real arterial.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real adipose.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real bone.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real brain.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real heart.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real muscle.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real skin.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real gut.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real spleen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real liver.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real kidney.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real gonads.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real rest.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real lumenCompartment.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real periodicOralDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real periodicOralDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real periodicOralDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real periodicIMDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real periodicIMDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real periodicIMDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real periodicIVDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real periodicIVDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real periodicIADose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real periodicIADose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real nasal_mucosa.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real periodicNasalDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real periodicNasalDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real periodicNasalDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real periodicNasalDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real periodicNasalDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real periodicIMDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real periodicIMDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real periodicOralDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real periodicOralDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real lumenCompartment.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real lumenCompartment.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real periodicNasalDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean periodicIMDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean periodicOralDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean lumenCompartment.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 55 * Number of states: 0 () * Number of discrete variables: 57 ($PRE.periodicNasalDose.absorptionLumen.Cmin,periodicNasalDose.absorptionLumen.Cmin,$PRE.periodicNasalDose.absorptionLumen.Cmax,periodicNasalDose.absorptionLumen.Cmax,$PRE.periodicIMDose.absorptionLumen.Cmin,periodicIMDose.absorptionLumen.Cmin,$PRE.periodicIMDose.absorptionLumen.Cmax,periodicIMDose.absorptionLumen.Cmax,$PRE.periodicOralDose.absorptionLumen.Cmin,periodicOralDose.absorptionLumen.Cmin,$PRE.periodicOralDose.absorptionLumen.Cmax,periodicOralDose.absorptionLumen.Cmax,$PRE.lumenCompartment.Cmin,lumenCompartment.Cmin,$PRE.lumenCompartment.Cmax,lumenCompartment.Cmax,$PRE.periodicNasalDose.pulse.count,$PRE.periodicNasalDose.pulse.T_start,$PRE.periodicNasalDose.absorptionLumen.rising,$PRE.periodicIADose.pulse.count,$PRE.periodicIADose.pulse.T_start,$PRE.periodicIVDose.pulse.count,$PRE.periodicIVDose.pulse.T_start,$PRE.periodicIMDose.pulse.count,$PRE.periodicIMDose.pulse.T_start,$PRE.periodicIMDose.absorptionLumen.rising,$PRE.periodicOralDose.pulse.count,$PRE.periodicOralDose.pulse.T_start,$PRE.periodicOralDose.absorptionLumen.rising,$PRE.lumenCompartment.rising,periodicNasalDose.pulse.count,periodicNasalDose.pulse.T_start,periodicNasalDose.absorptionLumen.rising,periodicIADose.pulse.count,periodicIADose.pulse.T_start,periodicIVDose.pulse.count,periodicIVDose.pulse.T_start,periodicIMDose.pulse.count,periodicIMDose.pulse.T_start,periodicIMDose.absorptionLumen.rising,periodicOralDose.pulse.count,periodicOralDose.pulse.T_start,periodicOralDose.absorptionLumen.rising,lumenCompartment.rising,$whenCondition8,$whenCondition7,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (289): * Single equations (assignments): 280 * Array equations: 0 * Algorithm blocks: 9 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.0007741/0.07318, allocations: 0.5797 MB / 0.7181 GB, free: 15.2 MB / 0.5574 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0003897/0.07357, allocations: 223 kB / 0.7183 GB, free: 14.98 MB / 0.5574 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.002977/0.07655, allocations: 2.544 MB / 0.7208 GB, free: 12.45 MB / 0.5574 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 1.227e-05/0.07656, allocations: 20 kB / 0.7208 GB, free: 12.43 MB / 0.5574 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 2.695e-06/0.07657, allocations: 4 kB / 0.7208 GB, free: 12.43 MB / 0.5574 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 1.404e-05/0.07658, allocations: 11.95 kB / 0.7208 GB, free: 12.41 MB / 0.5574 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.004069/0.08065, allocations: 3.316 MB / 0.7241 GB, free: 9.008 MB / 0.5574 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 4.669e-06/0.08065, allocations: 0 / 0.7241 GB, free: 9.008 MB / 0.5574 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.001267/0.08192, allocations: 443.3 kB / 0.7245 GB, free: 8.574 MB / 0.5574 GB Notification: Performance of postOpt tearingSystem (simulation): time 1.43e-05/0.08193, allocations: 8 kB / 0.7245 GB, free: 8.566 MB / 0.5574 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0001744/0.08211, allocations: 107.8 kB / 0.7246 GB, free: 8.461 MB / 0.5574 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 6.302e-06/0.08212, allocations: 8 kB / 0.7246 GB, free: 8.453 MB / 0.5574 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 1.794e-06/0.08212, allocations: 0 / 0.7246 GB, free: 8.453 MB / 0.5574 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.003252/0.08537, allocations: 2.82 MB / 0.7273 GB, free: 5.531 MB / 0.5574 GB Notification: Performance of postOpt removeConstants (simulation): time 0.0007304/0.0861, allocations: 390.6 kB / 0.7277 GB, free: 5.148 MB / 0.5574 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0002225/0.08632, allocations: 67.89 kB / 0.7278 GB, free: 5.082 MB / 0.5574 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.0007468/0.08707, allocations: 75.78 kB / 0.7279 GB, free: 5.012 MB / 0.5574 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0002193/0.08729, allocations: 165.7 kB / 0.728 GB, free: 4.848 MB / 0.5574 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 0.0001225/0.08741, allocations: 111.7 kB / 0.7281 GB, free: 4.738 MB / 0.5574 GB Notification: Performance of sorting global known variables: time 0.0003678/0.08778, allocations: 0.5371 MB / 0.7286 GB, free: 4.191 MB / 0.5574 GB Notification: Performance of sort global known variables: time 6e-08/0.08778, allocations: 0 / 0.7286 GB, free: 4.191 MB / 0.5574 GB Notification: Performance of remove unused functions: time 0.001616/0.08939, allocations: 0.6328 MB / 0.7293 GB, free: 3.559 MB / 0.5574 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 2 * Number of states: 52 (venous.M,venous.AUC,lungs.M,lungs.AUC,arterial.M,arterial.AUC,adipose.M,adipose.AUC,bone.M,bone.AUC,brain.M,brain.AUC,heart.M,heart.AUC,muscle.M,muscle.AUC,skin.M,skin.AUC,gut.M,gut.AUC,spleen.M,spleen.AUC,liver.M,liver.AUC,kidney.M,kidney.AUC,kidneyElim.MExc,liverElim.MExc,gonads.M,gonads.AUC,rest.M,rest.AUC,lumenCompartment.C,lumenCompartment.AUC,periodicOralDose.TotalCumulativeMass,periodicOralDose.absorptionLumen.C,periodicOralDose.absorptionLumen.AUC,periodicOralDose.variableDose.TotalCumulativeMass,periodicIMDose.TotalCumulativeMass,periodicIMDose.absorptionLumen.C,periodicIMDose.absorptionLumen.AUC,periodicIMDose.variableDose.TotalCumulativeMass,periodicIVDose.TotalCumulativeMass,periodicIVDose.variableDose.TotalCumulativeMass,periodicIADose.TotalCumulativeMass,periodicIADose.variableDose.TotalCumulativeMass,nasal_mucosa.M,nasal_mucosa.AUC,periodicNasalDose.TotalCumulativeMass,periodicNasalDose.absorptionLumen.C,periodicNasalDose.absorptionLumen.AUC,periodicNasalDose.variableDose.TotalCumulativeMass) * Number of discrete variables: 35 ($whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,$whenCondition7,$whenCondition8,lumenCompartment.Cmax,lumenCompartment.Cmin,lumenCompartment.rising,periodicOralDose.absorptionLumen.Cmax,periodicOralDose.absorptionLumen.Cmin,periodicOralDose.absorptionLumen.rising,periodicOralDose.pulse.T_start,periodicOralDose.pulse.count,periodicIMDose.absorptionLumen.Cmax,periodicIMDose.absorptionLumen.Cmin,periodicIMDose.absorptionLumen.rising,periodicIMDose.pulse.T_start,periodicIMDose.pulse.count,periodicIVDose.pulse.T_start,periodicIVDose.pulse.count,periodicIADose.pulse.T_start,periodicIADose.pulse.count,periodicNasalDose.absorptionLumen.Cmax,periodicNasalDose.absorptionLumen.Cmin,periodicNasalDose.absorptionLumen.rising,periodicNasalDose.pulse.T_start,periodicNasalDose.pulse.count) * Number of discrete states: 25 (periodicOralDose.pulse.count,periodicIMDose.pulse.count,periodicIVDose.pulse.count,periodicIADose.pulse.count,periodicNasalDose.pulse.count,periodicNasalDose.absorptionLumen.Cmin,$whenCondition8,periodicNasalDose.absorptionLumen.Cmax,$whenCondition7,periodicNasalDose.absorptionLumen.rising,periodicIMDose.absorptionLumen.Cmin,$whenCondition6,periodicIMDose.absorptionLumen.Cmax,$whenCondition5,periodicIMDose.absorptionLumen.rising,periodicOralDose.absorptionLumen.Cmin,$whenCondition4,periodicOralDose.absorptionLumen.Cmax,$whenCondition3,periodicOralDose.absorptionLumen.rising,lumenCompartment.Cmin,$whenCondition2,lumenCompartment.Cmax,$whenCondition1,lumenCompartment.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (190): * Single equations (assignments): 176 * Array equations: 0 * Algorithm blocks: 4 * Record equations: 0 * When equations: 10 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0003567/0.08975, allocations: 204.1 kB / 0.7295 GB, free: 3.355 MB / 0.5574 GB Notification: Performance of simCode: created initialization part: time 0.002928/0.09268, allocations: 2.474 MB / 0.7319 GB, free: 0.6875 MB / 0.5574 GB Notification: Performance of simCode: created event and clocks part: time 3.387e-06/0.09268, allocations: 8.125 kB / 0.7319 GB, free: 0.6797 MB / 0.5574 GB Notification: Performance of simCode: created simulation system equations: time 0.000997/0.09368, allocations: 1.108 MB / 0.733 GB, free: 15.49 MB / 0.573 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.001387/0.09507, allocations: 0.5716 MB / 0.7335 GB, free: 14.95 MB / 0.573 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.005779/0.1008, allocations: 5.069 MB / 0.7385 GB, free: 9.977 MB / 0.573 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.0002183/0.1011, allocations: 325.7 kB / 0.7388 GB, free: 9.633 MB / 0.573 GB Notification: Performance of simCode: alias equations: time 0.001319/0.1024, allocations: 0.4953 MB / 0.7393 GB, free: 9.266 MB / 0.573 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.001697/0.1041, allocations: 0.7903 MB / 0.74 GB, free: 8.473 MB / 0.573 GB Notification: Performance of SimCode: time 2.064e-06/0.1041, allocations: 0 / 0.74 GB, free: 8.473 MB / 0.573 GB Notification: Performance of Templates: time 0.04564/0.1497, allocations: 43.88 MB / 0.7829 GB, free: 13.62 MB / 0.6199 GB " [Timeout remaining time 660] make -j1 -f Pharmacolibrary_Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body.sim & ./Pharmacolibrary_Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body -abortSlowSimulation -alarm=240 -lv LOG_STATS > Pharmacolibrary_Pharmacolibrary.Pharmacokinetic.Models.PBPK_whole_body.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 5.614546871278435]