Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.001129/0.001129, allocations: 81.95 kB / 19.87 MB, free: 4.621 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.001192/0.001192, allocations: 169.7 kB / 23.28 MB, free: 1.223 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 1.008/1.008, allocations: 177.1 MB / 203.7 MB, free: 5.52 MB / 186.7 MB " [Timeout remaining time 179] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 1.622/1.622, allocations: 273.5 MB / 0.5212 GB, free: 14.69 MB / 458.7 MB " [Timeout remaining time 178] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") [Timeout 660] "Notification: Performance of FrontEnd - loaded program: time 2.735e-06/2.735e-06, allocations: 0 / 0.6474 GB, free: 38.48 MB / 0.5262 GB Notification: Performance of FrontEnd - Absyn->SCode: time 2.59e-05/2.863e-05, allocations: 4.562 kB / 0.6474 GB, free: 38.48 MB / 0.5262 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic): time 0.0121/0.01212, allocations: 13.08 MB / 0.6602 GB, free: 29.73 MB / 0.5262 GB Notification: Performance of NFInst.instExpressions: time 0.005544/0.01767, allocations: 2.671 MB / 0.6628 GB, free: 27.84 MB / 0.5262 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.001123/0.01879, allocations: 20.91 kB / 0.6628 GB, free: 27.84 MB / 0.5262 GB Notification: Performance of NFTyping.typeComponents: time 0.0004845/0.01928, allocations: 312.1 kB / 0.6631 GB, free: 27.66 MB / 0.5262 GB Notification: Performance of NFTyping.typeBindings: time 0.001514/0.02079, allocations: 0.9132 MB / 0.664 GB, free: 26.98 MB / 0.5262 GB Notification: Performance of NFTyping.typeClassSections: time 0.0009437/0.02173, allocations: 0.6777 MB / 0.6647 GB, free: 26.52 MB / 0.5262 GB Notification: Performance of NFFlatten.flatten: time 0.002418/0.02415, allocations: 3.262 MB / 0.6678 GB, free: 24.67 MB / 0.5262 GB Notification: Performance of NFFlatten.resolveConnections: time 0.0005924/0.02474, allocations: 455.1 kB / 0.6683 GB, free: 24.4 MB / 0.5262 GB Notification: Performance of NFEvalConstants.evaluate: time 0.001663/0.02641, allocations: 1.666 MB / 0.6699 GB, free: 23.65 MB / 0.5262 GB Notification: Performance of NFSimplifyModel.simplify: time 0.0009843/0.02739, allocations: 0.9355 MB / 0.6708 GB, free: 23.32 MB / 0.5262 GB Notification: Performance of NFPackage.collectConstants: time 0.0003049/0.0277, allocations: 281.9 kB / 0.6711 GB, free: 23.32 MB / 0.5262 GB Notification: Performance of NFFlatten.collectFunctions: time 0.0003744/0.02807, allocations: 284.8 kB / 0.6714 GB, free: 23.32 MB / 0.5262 GB Notification: Performance of NFScalarize.scalarize: time 0.0002146/0.02829, allocations: 0.5042 MB / 0.6718 GB, free: 22.95 MB / 0.5262 GB Notification: Performance of NFVerifyModel.verify: time 0.001761/0.03005, allocations: 0.952 MB / 0.6728 GB, free: 22.52 MB / 0.5262 GB Notification: Performance of NFConvertDAE.convert: time 0.002152/0.0322, allocations: 1.907 MB / 0.6746 GB, free: 21.49 MB / 0.5262 GB Notification: Performance of FrontEnd - DAE generated: time 6.632e-06/0.0322, allocations: 1.406 kB / 0.6746 GB, free: 21.49 MB / 0.5262 GB Notification: Performance of FrontEnd: time 1.153e-06/0.03221, allocations: 0 / 0.6746 GB, free: 21.49 MB / 0.5262 GB Notification: Performance of Transformations before backend: time 0.0001172/0.03232, allocations: 0 / 0.6746 GB, free: 21.49 MB / 0.5262 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 402 * Number of variables: 402 Notification: Performance of Generate backend data structure: time 0.003924/0.03625, allocations: 3.251 MB / 0.6778 GB, free: 19.06 MB / 0.5262 GB Notification: Performance of prepare preOptimizeDAE: time 4.211e-05/0.03629, allocations: 9.906 kB / 0.6778 GB, free: 19.06 MB / 0.5262 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.0004877/0.03678, allocations: 384.9 kB / 0.6782 GB, free: 18.88 MB / 0.5262 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.001017/0.03779, allocations: 0.9336 MB / 0.6791 GB, free: 18.23 MB / 0.5262 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 7.499e-05/0.03787, allocations: 127.1 kB / 0.6792 GB, free: 18.17 MB / 0.5262 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.0002276/0.0381, allocations: 195.7 kB / 0.6794 GB, free: 18.11 MB / 0.5262 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.001656/0.03975, allocations: 1.715 MB / 0.6811 GB, free: 17.06 MB / 0.5262 GB Notification: Performance of preOpt findStateOrder (simulation): time 8.663e-05/0.03984, allocations: 35.53 kB / 0.6811 GB, free: 17.04 MB / 0.5262 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 8.635e-05/0.03993, allocations: 65.44 kB / 0.6812 GB, free: 16.99 MB / 0.5262 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 2.596e-05/0.03995, allocations: 41.47 kB / 0.6812 GB, free: 16.99 MB / 0.5262 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.001107/0.04106, allocations: 1.245 MB / 0.6824 GB, free: 16.33 MB / 0.5262 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.004407/0.04547, allocations: 4.964 MB / 0.6873 GB, free: 12.88 MB / 0.5262 GB Notification: Performance of preOpt comSubExp (simulation): time 0.001151/0.04662, allocations: 1.35 MB / 0.6886 GB, free: 11.91 MB / 0.5262 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.0004571/0.04707, allocations: 0.8599 MB / 0.6894 GB, free: 11.15 MB / 0.5262 GB Notification: Performance of preOpt evalFunc (simulation): time 7.137e-05/0.04715, allocations: 46.61 kB / 0.6895 GB, free: 11.14 MB / 0.5262 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.00123/0.04838, allocations: 2.568 MB / 0.692 GB, free: 8.699 MB / 0.5262 GB Notification: Performance of pre-optimization done (n=264): time 4.699e-06/0.04838, allocations: 1.281 kB / 0.692 GB, free: 8.699 MB / 0.5262 GB Notification: Performance of matching and sorting (n=282): time 0.005375/0.05376, allocations: 7.057 MB / 0.6989 GB, free: 2.551 MB / 0.5262 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.0002007/0.05396, allocations: 1.648 MB / 0.7005 GB, free: 0.5273 MB / 0.5262 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.0007609/0.05472, allocations: 1.067 MB / 0.7015 GB, free: 15.43 MB / 0.5418 GB Notification: Performance of collectPreVariables (initialization): time 0.0001413/0.05486, allocations: 125.6 kB / 0.7017 GB, free: 15.3 MB / 0.5418 GB Notification: Performance of collectInitialEqns (initialization): time 0.0004238/0.05528, allocations: 0.7584 MB / 0.7024 GB, free: 14.53 MB / 0.5418 GB Notification: Performance of collectInitialBindings (initialization): time 0.00058/0.05586, allocations: 0.9298 MB / 0.7033 GB, free: 13.59 MB / 0.5418 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0005103/0.05637, allocations: 494.3 kB / 0.7038 GB, free: 13.1 MB / 0.5418 GB Notification: Performance of setup shared object (initialization): time 0.0001002/0.05647, allocations: 484.7 kB / 0.7042 GB, free: 12.62 MB / 0.5418 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.0008512/0.05732, allocations: 1.097 MB / 0.7053 GB, free: 11.36 MB / 0.5418 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.001175/0.0585, allocations: 2.146 MB / 0.7074 GB, free: 8.602 MB / 0.5418 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.002412/0.06091, allocations: 4.007 MB / 0.7113 GB, free: 3.785 MB / 0.5418 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 2.63e-05/0.06094, allocations: 8 kB / 0.7113 GB, free: 3.777 MB / 0.5418 GB Notification: Performance of matching and sorting (n=426) (initialization): time 0.002929/0.06387, allocations: 3.429 MB / 0.7147 GB, free: 44 kB / 0.5418 GB Notification: Performance of prepare postOptimizeDAE: time 0.0002357/0.0641, allocations: 0.6726 MB / 0.7153 GB, free: 15.22 MB / 0.5574 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 2.844e-05/0.06413, allocations: 20 kB / 0.7153 GB, free: 15.2 MB / 0.5574 GB Notification: Performance of postOpt tearingSystem (initialization): time 4.654e-05/0.06418, allocations: 36.72 kB / 0.7154 GB, free: 15.17 MB / 0.5574 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.001205/0.06538, allocations: 0.6708 MB / 0.716 GB, free: 14.5 MB / 0.5574 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 4.052e-05/0.06542, allocations: 51.86 kB / 0.7161 GB, free: 14.45 MB / 0.5574 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.001151/0.06657, allocations: 139.5 kB / 0.7162 GB, free: 14.31 MB / 0.5574 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.000128/0.0667, allocations: 112 kB / 0.7163 GB, free: 14.2 MB / 0.5574 GB Warning: Assuming fixed start value for the following 84 variables: ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 174 ($PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (402): * Single equations (assignments): 378 * Array equations: 0 * Algorithm blocks: 24 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.001444/0.06815, allocations: 1.289 MB / 0.7176 GB, free: 12.84 MB / 0.5574 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0003638/0.06851, allocations: 338.6 kB / 0.7179 GB, free: 12.5 MB / 0.5574 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.0002175/0.06873, allocations: 208.9 kB / 0.7181 GB, free: 12.3 MB / 0.5574 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 1.448e-05/0.06874, allocations: 24 kB / 0.7181 GB, free: 12.27 MB / 0.5574 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 1.879e-05/0.06876, allocations: 0 / 0.7181 GB, free: 12.27 MB / 0.5574 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 1.726e-05/0.06878, allocations: 15.95 kB / 0.7181 GB, free: 12.26 MB / 0.5574 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.004479/0.07326, allocations: 5.138 MB / 0.7232 GB, free: 6.859 MB / 0.5574 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 6.452e-06/0.07326, allocations: 0 / 0.7232 GB, free: 6.859 MB / 0.5574 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.001068/0.07433, allocations: 427.5 kB / 0.7236 GB, free: 6.441 MB / 0.5574 GB Notification: Performance of postOpt tearingSystem (simulation): time 1.997e-05/0.07435, allocations: 12 kB / 0.7236 GB, free: 6.43 MB / 0.5574 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0004406/0.07479, allocations: 91.95 kB / 0.7237 GB, free: 6.34 MB / 0.5574 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 8.857e-06/0.0748, allocations: 15.94 kB / 0.7237 GB, free: 6.324 MB / 0.5574 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 3.086e-06/0.0748, allocations: 4 kB / 0.7237 GB, free: 6.32 MB / 0.5574 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.003454/0.07826, allocations: 4.859 MB / 0.7284 GB, free: 1.051 MB / 0.5574 GB Notification: Performance of postOpt removeConstants (simulation): time 0.000703/0.07896, allocations: 434.3 kB / 0.7289 GB, free: 0.625 MB / 0.5574 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0002816/0.07924, allocations: 119.2 kB / 0.729 GB, free: 0.5117 MB / 0.5574 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.0006467/0.07989, allocations: 103.9 kB / 0.7291 GB, free: 420 kB / 0.5574 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0003098/0.0802, allocations: 251.3 kB / 0.7293 GB, free: 168 kB / 0.5574 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 9.638e-05/0.0803, allocations: 91.89 kB / 0.7294 GB, free: 76 kB / 0.5574 GB Notification: Performance of sorting global known variables: time 0.0004884/0.08078, allocations: 0.6152 MB / 0.73 GB, free: 15.45 MB / 0.573 GB Notification: Performance of sort global known variables: time 8.1e-08/0.08078, allocations: 0 / 0.73 GB, free: 15.45 MB / 0.573 GB Notification: Performance of remove unused functions: time 0.001787/0.08257, allocations: 0.6562 MB / 0.7306 GB, free: 14.8 MB / 0.573 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC) * Number of discrete variables: 108 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising) * Number of discrete states: 96 (patient.periodicDose.pulse.count,patient.peripheral.Cmin,$whenCondition41,patient.peripheral.Cmax,$whenCondition40,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition39,patient.periodicDose.absorptionLumen.Cmax,$whenCondition38,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition37,patient.central.Cmax,$whenCondition36,patient.central.rising,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmin,$whenCondition34,patient_high.peripheral.Cmax,$whenCondition33,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition32,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition31,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition30,patient_high.central.Cmax,$whenCondition29,patient_high.central.rising,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmin,$whenCondition27,patient_low.peripheral.Cmax,$whenCondition26,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition25,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition24,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition23,patient_low.central.Cmax,$whenCondition22,patient_low.central.rising,ref.periodicDose.pulse.count,ref.peripheral.Cmin,$whenCondition20,ref.peripheral.Cmax,$whenCondition19,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition18,ref.periodicDose.absorptionLumen.Cmax,$whenCondition17,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition16,ref.central.Cmax,$whenCondition15,ref.central.rising,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmin,$whenCondition13,ref_high.peripheral.Cmax,$whenCondition12,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition11,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition10,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition9,ref_high.central.Cmax,$whenCondition8,ref_high.central.rising,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmin,$whenCondition6,ref_low.peripheral.Cmax,$whenCondition5,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition4,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition3,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition2,ref_low.central.Cmax,$whenCondition1,ref_low.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (228): * Single equations (assignments): 198 * Array equations: 0 * Algorithm blocks: 18 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0003253/0.0829, allocations: 352.5 kB / 0.731 GB, free: 14.46 MB / 0.573 GB Notification: Performance of simCode: created initialization part: time 0.00251/0.08541, allocations: 3.875 MB / 0.7348 GB, free: 10.02 MB / 0.573 GB Notification: Performance of simCode: created event and clocks part: time 2.926e-06/0.08541, allocations: 0 / 0.7348 GB, free: 10.02 MB / 0.573 GB Notification: Performance of simCode: created simulation system equations: time 0.001482/0.08689, allocations: 2.266 MB / 0.737 GB, free: 7.414 MB / 0.573 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.001865/0.08876, allocations: 0.7092 MB / 0.7377 GB, free: 6.758 MB / 0.573 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.007033/0.09579, allocations: 5.796 MB / 0.7433 GB, free: 0.957 MB / 0.573 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.0004025/0.09619, allocations: 389.5 kB / 0.7437 GB, free: 0.5469 MB / 0.573 GB Notification: Performance of simCode: alias equations: time 0.001088/0.09728, allocations: 243.1 kB / 0.7439 GB, free: 328 kB / 0.573 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.0018/0.09908, allocations: 0.8805 MB / 0.7448 GB, free: 15.44 MB / 0.5887 GB Notification: Performance of SimCode: time 1.954e-06/0.09908, allocations: 7.938 kB / 0.7448 GB, free: 15.43 MB / 0.5887 GB Notification: Performance of Templates: time 0.04779/0.1469, allocations: 39.64 MB / 0.7835 GB, free: 9.695 MB / 0.6199 GB " [Timeout remaining time 660] make -j1 -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.sim & ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic -abortSlowSimulation -alarm=240 -lv LOG_STATS > Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 5.681430482771248]