Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.001406/0.001406, allocations: 92.22 kB / 19.65 MB, free: 276 kB / 13.93 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.001768/0.001768, allocations: 169 kB / 23.02 MB, free: 1.551 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 0.9716/0.9716, allocations: 177.1 MB / 203.4 MB, free: 5.633 MB / 186.7 MB " [Timeout remaining time 179] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 1.588/1.588, allocations: 273.5 MB / 0.5209 GB, free: 14.84 MB / 458.7 MB " [Timeout remaining time 178] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") [Timeout 660] "Notification: Performance of FrontEnd - loaded program: time 3.135e-06/3.135e-06, allocations: 0 / 0.647 GB, free: 38.66 MB / 0.5262 GB Notification: Performance of FrontEnd - Absyn->SCode: time 2.501e-05/2.814e-05, allocations: 4.531 kB / 0.647 GB, free: 38.65 MB / 0.5262 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic): time 0.009345/0.009373, allocations: 13.41 MB / 0.6601 GB, free: 29.91 MB / 0.5262 GB Notification: Performance of NFInst.instExpressions: time 0.004828/0.0142, allocations: 2.683 MB / 0.6627 GB, free: 28.01 MB / 0.5262 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.0008694/0.01507, allocations: 20.72 kB / 0.6627 GB, free: 28.01 MB / 0.5262 GB Notification: Performance of NFTyping.typeComponents: time 0.0004743/0.01554, allocations: 307.1 kB / 0.663 GB, free: 27.84 MB / 0.5262 GB Notification: Performance of NFTyping.typeBindings: time 0.001336/0.01688, allocations: 0.916 MB / 0.6639 GB, free: 27.15 MB / 0.5262 GB Notification: Performance of NFTyping.typeClassSections: time 0.00096/0.01784, allocations: 0.6665 MB / 0.6645 GB, free: 26.7 MB / 0.5262 GB Notification: Performance of NFFlatten.flatten: time 0.002188/0.02003, allocations: 3.272 MB / 0.6677 GB, free: 24.84 MB / 0.5262 GB Notification: Performance of NFFlatten.resolveConnections: time 0.0006005/0.02063, allocations: 453.2 kB / 0.6682 GB, free: 24.57 MB / 0.5262 GB Notification: Performance of NFEvalConstants.evaluate: time 0.001844/0.02247, allocations: 1.654 MB / 0.6698 GB, free: 23.83 MB / 0.5262 GB Notification: Performance of NFSimplifyModel.simplify: time 0.001105/0.02358, allocations: 0.9423 MB / 0.6707 GB, free: 23.5 MB / 0.5262 GB Notification: Performance of NFPackage.collectConstants: time 0.0003109/0.02389, allocations: 281.3 kB / 0.671 GB, free: 23.5 MB / 0.5262 GB Notification: Performance of NFFlatten.collectFunctions: time 0.0003873/0.02428, allocations: 286 kB / 0.6712 GB, free: 23.5 MB / 0.5262 GB Notification: Performance of NFScalarize.scalarize: time 0.0002567/0.02453, allocations: 0.5051 MB / 0.6717 GB, free: 23.12 MB / 0.5262 GB Notification: Performance of NFVerifyModel.verify: time 0.0009614/0.0255, allocations: 0.9535 MB / 0.6727 GB, free: 22.69 MB / 0.5262 GB Notification: Performance of NFConvertDAE.convert: time 0.002067/0.02756, allocations: 1.909 MB / 0.6745 GB, free: 21.66 MB / 0.5262 GB Notification: Performance of FrontEnd - DAE generated: time 6.382e-06/0.02757, allocations: 4 kB / 0.6745 GB, free: 21.66 MB / 0.5262 GB Notification: Performance of FrontEnd: time 2.364e-06/0.02757, allocations: 0 / 0.6745 GB, free: 21.66 MB / 0.5262 GB Notification: Performance of Transformations before backend: time 2.77e-05/0.0276, allocations: 0 / 0.6745 GB, free: 21.66 MB / 0.5262 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 402 * Number of variables: 402 Notification: Performance of Generate backend data structure: time 0.00301/0.03061, allocations: 3.222 MB / 0.6777 GB, free: 19.25 MB / 0.5262 GB Notification: Performance of prepare preOptimizeDAE: time 4.376e-05/0.03065, allocations: 12.47 kB / 0.6777 GB, free: 19.25 MB / 0.5262 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.0004155/0.03107, allocations: 380.5 kB / 0.678 GB, free: 19.08 MB / 0.5262 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.001066/0.03213, allocations: 0.9572 MB / 0.679 GB, free: 18.41 MB / 0.5262 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 8.231e-05/0.03222, allocations: 123 kB / 0.6791 GB, free: 18.36 MB / 0.5262 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.000216/0.03243, allocations: 194.9 kB / 0.6793 GB, free: 18.29 MB / 0.5262 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.0019/0.03433, allocations: 1.815 MB / 0.6811 GB, free: 17.2 MB / 0.5262 GB Notification: Performance of preOpt findStateOrder (simulation): time 5.901e-05/0.03439, allocations: 34.75 kB / 0.6811 GB, free: 17.18 MB / 0.5262 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 8.694e-05/0.03448, allocations: 64.66 kB / 0.6812 GB, free: 17.14 MB / 0.5262 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 2.794e-05/0.03451, allocations: 41.16 kB / 0.6812 GB, free: 17.14 MB / 0.5262 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.001346/0.03585, allocations: 1.353 MB / 0.6825 GB, free: 16.44 MB / 0.5262 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.005381/0.04123, allocations: 5.119 MB / 0.6875 GB, free: 12.93 MB / 0.5262 GB Notification: Performance of preOpt comSubExp (simulation): time 0.001667/0.0429, allocations: 1.432 MB / 0.6889 GB, free: 11.98 MB / 0.5262 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.0006944/0.04359, allocations: 0.9283 MB / 0.6898 GB, free: 11.2 MB / 0.5262 GB Notification: Performance of preOpt evalFunc (simulation): time 8.534e-05/0.04368, allocations: 38.7 kB / 0.6899 GB, free: 11.2 MB / 0.5262 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.001448/0.04513, allocations: 2.634 MB / 0.6924 GB, free: 8.727 MB / 0.5262 GB Notification: Performance of pre-optimization done (n=264): time 4.769e-06/0.04513, allocations: 3.797 kB / 0.6924 GB, free: 8.727 MB / 0.5262 GB Notification: Performance of matching and sorting (n=282): time 0.007238/0.05237, allocations: 8.776 MB / 0.701 GB, free: 220 kB / 0.5262 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.0005305/0.0529, allocations: 1.648 MB / 0.7026 GB, free: 14.19 MB / 0.5418 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.001086/0.05399, allocations: 1.118 MB / 0.7037 GB, free: 13.04 MB / 0.5418 GB Notification: Performance of collectPreVariables (initialization): time 0.0001263/0.05411, allocations: 117.7 kB / 0.7038 GB, free: 12.92 MB / 0.5418 GB Notification: Performance of collectInitialEqns (initialization): time 0.0004283/0.05454, allocations: 0.7508 MB / 0.7045 GB, free: 12.16 MB / 0.5418 GB Notification: Performance of collectInitialBindings (initialization): time 0.0006716/0.05521, allocations: 0.9106 MB / 0.7054 GB, free: 11.24 MB / 0.5418 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0004804/0.05569, allocations: 482.6 kB / 0.7059 GB, free: 10.76 MB / 0.5418 GB Notification: Performance of setup shared object (initialization): time 0.0001015/0.0558, allocations: 480.7 kB / 0.7064 GB, free: 10.29 MB / 0.5418 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.000989/0.05678, allocations: 1.179 MB / 0.7075 GB, free: 8.945 MB / 0.5418 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.001666/0.05845, allocations: 2.228 MB / 0.7097 GB, free: 6.102 MB / 0.5418 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.003247/0.0617, allocations: 4.21 MB / 0.7138 GB, free: 1.082 MB / 0.5418 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 3.852e-05/0.06174, allocations: 8 kB / 0.7138 GB, free: 1.074 MB / 0.5418 GB Notification: Performance of matching and sorting (n=426) (initialization): time 0.00409/0.06583, allocations: 3.632 MB / 0.7173 GB, free: 13.13 MB / 0.5574 GB Notification: Performance of prepare postOptimizeDAE: time 0.0002468/0.06607, allocations: 0.6765 MB / 0.718 GB, free: 12.31 MB / 0.5574 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 2.485e-05/0.0661, allocations: 20 kB / 0.718 GB, free: 12.29 MB / 0.5574 GB Notification: Performance of postOpt tearingSystem (initialization): time 4.468e-05/0.06614, allocations: 36 kB / 0.7181 GB, free: 12.25 MB / 0.5574 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.001296/0.06744, allocations: 0.6597 MB / 0.7187 GB, free: 11.59 MB / 0.5574 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 3.609e-05/0.06747, allocations: 55.84 kB / 0.7188 GB, free: 11.54 MB / 0.5574 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.001199/0.06867, allocations: 131.9 kB / 0.7189 GB, free: 11.41 MB / 0.5574 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.0001415/0.06881, allocations: 136 kB / 0.719 GB, free: 11.28 MB / 0.5574 GB Warning: Assuming fixed start value for the following 84 variables: ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 174 ($PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (402): * Single equations (assignments): 378 * Array equations: 0 * Algorithm blocks: 24 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.001263/0.07008, allocations: 1.284 MB / 0.7203 GB, free: 9.922 MB / 0.5574 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0003528/0.07043, allocations: 338.7 kB / 0.7206 GB, free: 9.59 MB / 0.5574 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.0002013/0.07063, allocations: 204.9 kB / 0.7208 GB, free: 9.387 MB / 0.5574 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 1.422e-05/0.07065, allocations: 24 kB / 0.7208 GB, free: 9.363 MB / 0.5574 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 1.671e-05/0.07066, allocations: 4 kB / 0.7208 GB, free: 9.359 MB / 0.5574 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 1.536e-05/0.07068, allocations: 11.95 kB / 0.7208 GB, free: 9.348 MB / 0.5574 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.005289/0.07597, allocations: 5.451 MB / 0.7262 GB, free: 3.625 MB / 0.5574 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 6.732e-06/0.07597, allocations: 8 kB / 0.7262 GB, free: 3.617 MB / 0.5574 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.001062/0.07703, allocations: 427.4 kB / 0.7266 GB, free: 3.199 MB / 0.5574 GB Notification: Performance of postOpt tearingSystem (simulation): time 1.299e-05/0.07705, allocations: 8 kB / 0.7266 GB, free: 3.191 MB / 0.5574 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.000136/0.07718, allocations: 99.94 kB / 0.7267 GB, free: 3.094 MB / 0.5574 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 9.207e-06/0.07719, allocations: 8 kB / 0.7267 GB, free: 3.086 MB / 0.5574 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 4.348e-06/0.0772, allocations: 8 kB / 0.7267 GB, free: 3.078 MB / 0.5574 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.004134/0.08133, allocations: 5.093 MB / 0.7317 GB, free: 13.57 MB / 0.573 GB Notification: Performance of postOpt removeConstants (simulation): time 0.0007472/0.08208, allocations: 430.5 kB / 0.7321 GB, free: 13.15 MB / 0.573 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0002965/0.08238, allocations: 120 kB / 0.7322 GB, free: 13.04 MB / 0.573 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.0006399/0.08302, allocations: 99.23 kB / 0.7323 GB, free: 12.94 MB / 0.573 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0003314/0.08335, allocations: 255.3 kB / 0.7325 GB, free: 12.69 MB / 0.573 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 0.000106/0.08345, allocations: 95.94 kB / 0.7326 GB, free: 12.6 MB / 0.573 GB Notification: Performance of sorting global known variables: time 0.0006679/0.08412, allocations: 0.6856 MB / 0.7333 GB, free: 11.91 MB / 0.573 GB Notification: Performance of sort global known variables: time 2.41e-07/0.08412, allocations: 0 / 0.7333 GB, free: 11.91 MB / 0.573 GB Notification: Performance of remove unused functions: time 0.001531/0.08565, allocations: 0.6562 MB / 0.7339 GB, free: 11.25 MB / 0.573 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC) * Number of discrete variables: 108 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising) * Number of discrete states: 96 (patient.periodicDose.pulse.count,patient.peripheral.Cmin,$whenCondition41,patient.peripheral.Cmax,$whenCondition40,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition39,patient.periodicDose.absorptionLumen.Cmax,$whenCondition38,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition37,patient.central.Cmax,$whenCondition36,patient.central.rising,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmin,$whenCondition34,patient_high.peripheral.Cmax,$whenCondition33,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition32,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition31,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition30,patient_high.central.Cmax,$whenCondition29,patient_high.central.rising,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmin,$whenCondition27,patient_low.peripheral.Cmax,$whenCondition26,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition25,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition24,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition23,patient_low.central.Cmax,$whenCondition22,patient_low.central.rising,ref.periodicDose.pulse.count,ref.peripheral.Cmin,$whenCondition20,ref.peripheral.Cmax,$whenCondition19,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition18,ref.periodicDose.absorptionLumen.Cmax,$whenCondition17,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition16,ref.central.Cmax,$whenCondition15,ref.central.rising,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmin,$whenCondition13,ref_high.peripheral.Cmax,$whenCondition12,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition11,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition10,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition9,ref_high.central.Cmax,$whenCondition8,ref_high.central.rising,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmin,$whenCondition6,ref_low.peripheral.Cmax,$whenCondition5,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition4,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition3,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition2,ref_low.central.Cmax,$whenCondition1,ref_low.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (228): * Single equations (assignments): 198 * Array equations: 0 * Algorithm blocks: 18 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0003086/0.08596, allocations: 336 kB / 0.7342 GB, free: 10.92 MB / 0.573 GB Notification: Performance of simCode: created initialization part: time 0.00365/0.08961, allocations: 4.062 MB / 0.7382 GB, free: 6.301 MB / 0.573 GB Notification: Performance of simCode: created event and clocks part: time 3.848e-06/0.08961, allocations: 0 / 0.7382 GB, free: 6.301 MB / 0.573 GB Notification: Performance of simCode: created simulation system equations: time 0.001596/0.09121, allocations: 2.346 MB / 0.7405 GB, free: 3.617 MB / 0.573 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.002385/0.09359, allocations: 0.7101 MB / 0.7412 GB, free: 2.961 MB / 0.573 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.007524/0.1011, allocations: 5.867 MB / 0.7469 GB, free: 13.09 MB / 0.5887 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.0003028/0.1014, allocations: 389.6 kB / 0.7473 GB, free: 12.68 MB / 0.5887 GB Notification: Performance of simCode: alias equations: time 0.000895/0.1023, allocations: 239.8 kB / 0.7475 GB, free: 12.45 MB / 0.5887 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.0003317/0.1026, allocations: 164.5 kB / 0.7477 GB, free: 12.29 MB / 0.5887 GB Notification: Performance of SimCode: time 1.874e-06/0.1027, allocations: 0 / 0.7477 GB, free: 12.29 MB / 0.5887 GB Notification: Performance of Templates: time 0.04405/0.1467, allocations: 36.03 MB / 0.7829 GB, free: 10.1 MB / 0.6199 GB " [Timeout remaining time 660] make -j1 -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.sim & ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic -abortSlowSimulation -alarm=240 -lv LOG_STATS > Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 5.731269578915089]