Environment - simulationEnvironment: startTime=0 stopTime=864000 tolerance=1e-06 numberOfIntervals=86400 stepSize=10 Regular simulation: ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment -abortSlowSimulation -alarm=240 -lv LOG_STATS LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient4.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient4.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient_citalopram_CYP2C19_2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_CYP2C19_2.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient2.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient_citalopram_normal.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_normal.dose.absorptionLumen.M, has value: -1e-10" LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0.00750743s reading init.xml | | | | | | 0.000489618s reading info.xml | | | | | | 0.000131827s [ 0.0%] pre-initialization | | | | | | 0.000130665s [ 0.0%] initialization | | | | | | 7.454e-06s [ 0.0%] steps | | | | | | 0.0320464s [ 4.3%] solver (excl. callbacks) | | | | | | 0s [ 0.0%] creating output-file | | | | | | 0.280512s [ 37.3%] event-handling | | | | | | 0.0196754s [ 2.6%] overhead | | | | | | 0.420179s [ 55.8%] simulation | | | | | | 0.752683s [100.0%] total | | | | | events | | | | | | 111 state events | | | | | | 0 time events | | | | | solver: dassl | | | | | | 1310 steps taken | | | | | | 1678 calls of functionODE | | | | | | 998 evaluations of jacobian | | | | | | 55 error test failures | | | | | | 0 convergence test failures | | | | | | 0.00716703s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.