Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.0009451/0.0009451, allocations: 88.23 kB / 19.42 MB, free: 492 kB / 13.93 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.002054/0.002054, allocations: 169 kB / 22.73 MB, free: 1.82 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 1.041/1.041, allocations: 177.1 MB / 203.1 MB, free: 5.637 MB / 186.7 MB " [Timeout remaining time 179] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 1.656/1.656, allocations: 273.5 MB / 0.5205 GB, free: 14.82 MB / 458.7 MB " [Timeout remaining time 178] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") [Timeout 660] "Notification: Performance of FrontEnd - loaded program: time 3.316e-06/3.316e-06, allocations: 1.312 kB / 0.6462 GB, free: 38.62 MB / 0.5262 GB Notification: Performance of FrontEnd - Absyn->SCode: time 3.325e-05/3.657e-05, allocations: 2.312 kB / 0.6462 GB, free: 38.62 MB / 0.5262 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic): time 0.01043/0.01047, allocations: 13.41 MB / 0.6593 GB, free: 29.88 MB / 0.5262 GB Notification: Performance of NFInst.instExpressions: time 0.005041/0.01551, allocations: 2.677 MB / 0.6619 GB, free: 27.98 MB / 0.5262 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.001418/0.01693, allocations: 22.62 kB / 0.662 GB, free: 27.98 MB / 0.5262 GB Notification: Performance of NFTyping.typeComponents: time 0.0005939/0.01752, allocations: 306.2 kB / 0.6623 GB, free: 27.8 MB / 0.5262 GB Notification: Performance of NFTyping.typeBindings: time 0.001704/0.01923, allocations: 0.9119 MB / 0.6631 GB, free: 27.12 MB / 0.5262 GB Notification: Performance of NFTyping.typeClassSections: time 0.001367/0.02059, allocations: 0.6722 MB / 0.6638 GB, free: 26.67 MB / 0.5262 GB Notification: Performance of NFFlatten.flatten: time 0.004172/0.02476, allocations: 3.268 MB / 0.667 GB, free: 24.82 MB / 0.5262 GB Notification: Performance of NFFlatten.resolveConnections: time 0.00411/0.02887, allocations: 455.7 kB / 0.6674 GB, free: 24.55 MB / 0.5262 GB Notification: Performance of NFEvalConstants.evaluate: time 0.00343/0.0323, allocations: 1.658 MB / 0.669 GB, free: 23.8 MB / 0.5262 GB Notification: Performance of NFSimplifyModel.simplify: time 0.002209/0.03451, allocations: 0.9352 MB / 0.67 GB, free: 23.48 MB / 0.5262 GB Notification: Performance of NFPackage.collectConstants: time 0.0007591/0.03527, allocations: 287 kB / 0.6702 GB, free: 23.48 MB / 0.5262 GB Notification: Performance of NFFlatten.collectFunctions: time 0.000899/0.03617, allocations: 283.9 kB / 0.6705 GB, free: 23.48 MB / 0.5262 GB Notification: Performance of NFScalarize.scalarize: time 0.0004099/0.03658, allocations: 0.505 MB / 0.671 GB, free: 23.1 MB / 0.5262 GB Notification: Performance of NFVerifyModel.verify: time 0.001895/0.03848, allocations: 0.9458 MB / 0.6719 GB, free: 22.68 MB / 0.5262 GB Notification: Performance of NFConvertDAE.convert: time 0.003337/0.04181, allocations: 1.909 MB / 0.6738 GB, free: 21.65 MB / 0.5262 GB Notification: Performance of FrontEnd - DAE generated: time 6.973e-06/0.04182, allocations: 0.6875 kB / 0.6738 GB, free: 21.65 MB / 0.5262 GB Notification: Performance of FrontEnd: time 2.625e-06/0.04182, allocations: 1.688 kB / 0.6738 GB, free: 21.65 MB / 0.5262 GB Notification: Performance of Transformations before backend: time 0.0001085/0.04193, allocations: 0 / 0.6738 GB, free: 21.65 MB / 0.5262 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 402 * Number of variables: 402 Notification: Performance of Generate backend data structure: time 0.005152/0.04708, allocations: 3.222 MB / 0.6769 GB, free: 19.24 MB / 0.5262 GB Notification: Performance of prepare preOptimizeDAE: time 4.88e-05/0.04713, allocations: 8.406 kB / 0.6769 GB, free: 19.24 MB / 0.5262 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.0006422/0.04777, allocations: 385.6 kB / 0.6773 GB, free: 19.07 MB / 0.5262 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.001677/0.04945, allocations: 0.9507 MB / 0.6782 GB, free: 18.4 MB / 0.5262 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 0.0001061/0.04956, allocations: 125.6 kB / 0.6784 GB, free: 18.35 MB / 0.5262 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.0003179/0.04988, allocations: 202.5 kB / 0.6785 GB, free: 18.28 MB / 0.5262 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.002927/0.0528, allocations: 1.817 MB / 0.6803 GB, free: 17.18 MB / 0.5262 GB Notification: Performance of preOpt findStateOrder (simulation): time 0.0001165/0.05292, allocations: 31.58 kB / 0.6804 GB, free: 17.16 MB / 0.5262 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 0.0001467/0.05307, allocations: 66.02 kB / 0.6804 GB, free: 17.12 MB / 0.5262 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 4.695e-05/0.05311, allocations: 36.53 kB / 0.6805 GB, free: 17.12 MB / 0.5262 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.002067/0.05518, allocations: 1.352 MB / 0.6818 GB, free: 16.42 MB / 0.5262 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.00575/0.06093, allocations: 5.131 MB / 0.6868 GB, free: 12.9 MB / 0.5262 GB Notification: Performance of preOpt comSubExp (simulation): time 0.00147/0.0624, allocations: 1.425 MB / 0.6882 GB, free: 11.95 MB / 0.5262 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.0006429/0.06304, allocations: 0.9254 MB / 0.6891 GB, free: 11.16 MB / 0.5262 GB Notification: Performance of preOpt evalFunc (simulation): time 7.845e-05/0.06312, allocations: 38.64 kB / 0.6891 GB, free: 11.15 MB / 0.5262 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.001431/0.06455, allocations: 2.639 MB / 0.6917 GB, free: 8.68 MB / 0.5262 GB Notification: Performance of pre-optimization done (n=264): time 3.747e-06/0.06456, allocations: 0 / 0.6917 GB, free: 8.68 MB / 0.5262 GB Notification: Performance of matching and sorting (n=282): time 0.008/0.07256, allocations: 8.778 MB / 0.7003 GB, free: 0.5156 MB / 0.5262 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.0006849/0.07324, allocations: 1.648 MB / 0.7019 GB, free: 14.49 MB / 0.5418 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.001166/0.07441, allocations: 1.114 MB / 0.703 GB, free: 13.34 MB / 0.5418 GB Notification: Performance of collectPreVariables (initialization): time 0.0001506/0.07456, allocations: 121.7 kB / 0.7031 GB, free: 13.22 MB / 0.5418 GB Notification: Performance of collectInitialEqns (initialization): time 0.0004576/0.07502, allocations: 0.7508 MB / 0.7038 GB, free: 12.46 MB / 0.5418 GB Notification: Performance of collectInitialBindings (initialization): time 0.0006127/0.07563, allocations: 0.9144 MB / 0.7047 GB, free: 11.54 MB / 0.5418 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0005286/0.07616, allocations: 482.6 kB / 0.7052 GB, free: 11.05 MB / 0.5418 GB Notification: Performance of setup shared object (initialization): time 0.0001063/0.07626, allocations: 484.7 kB / 0.7056 GB, free: 10.58 MB / 0.5418 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.001017/0.07728, allocations: 1.179 MB / 0.7068 GB, free: 9.238 MB / 0.5418 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.001464/0.07874, allocations: 2.216 MB / 0.7089 GB, free: 6.406 MB / 0.5418 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.003135/0.08188, allocations: 4.218 MB / 0.7131 GB, free: 1.379 MB / 0.5418 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 2.142e-05/0.0819, allocations: 8 kB / 0.7131 GB, free: 1.371 MB / 0.5418 GB Notification: Performance of matching and sorting (n=426) (initialization): time 0.003432/0.08533, allocations: 3.625 MB / 0.7166 GB, free: 13.44 MB / 0.5574 GB Notification: Performance of prepare postOptimizeDAE: time 0.0002311/0.08556, allocations: 0.6765 MB / 0.7173 GB, free: 12.61 MB / 0.5574 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 2.473e-05/0.08559, allocations: 24 kB / 0.7173 GB, free: 12.59 MB / 0.5574 GB Notification: Performance of postOpt tearingSystem (initialization): time 4.711e-05/0.08564, allocations: 36 kB / 0.7173 GB, free: 12.55 MB / 0.5574 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.001305/0.08694, allocations: 0.663 MB / 0.718 GB, free: 11.89 MB / 0.5574 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 3.812e-05/0.08698, allocations: 47.95 kB / 0.718 GB, free: 11.84 MB / 0.5574 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.0007727/0.08775, allocations: 139.9 kB / 0.7182 GB, free: 11.71 MB / 0.5574 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.0001482/0.0879, allocations: 136 kB / 0.7183 GB, free: 11.57 MB / 0.5574 GB Warning: Assuming fixed start value for the following 84 variables: ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 174 ($PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (402): * Single equations (assignments): 378 * Array equations: 0 * Algorithm blocks: 24 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.001132/0.08903, allocations: 1.287 MB / 0.7195 GB, free: 10.21 MB / 0.5574 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0003168/0.08935, allocations: 334.7 kB / 0.7199 GB, free: 9.887 MB / 0.5574 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.0002133/0.08956, allocations: 208.9 kB / 0.7201 GB, free: 9.68 MB / 0.5574 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 1.296e-05/0.08957, allocations: 24 kB / 0.7201 GB, free: 9.656 MB / 0.5574 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 1.277e-05/0.08959, allocations: 0 / 0.7201 GB, free: 9.656 MB / 0.5574 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 1.644e-05/0.0896, allocations: 15.95 kB / 0.7201 GB, free: 9.641 MB / 0.5574 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.004963/0.09457, allocations: 5.447 MB / 0.7254 GB, free: 3.926 MB / 0.5574 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 5.23e-06/0.09457, allocations: 0 / 0.7254 GB, free: 3.926 MB / 0.5574 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.001076/0.09565, allocations: 427.5 kB / 0.7258 GB, free: 3.508 MB / 0.5574 GB Notification: Performance of postOpt tearingSystem (simulation): time 1.103e-05/0.09566, allocations: 11.98 kB / 0.7258 GB, free: 3.496 MB / 0.5574 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0001392/0.0958, allocations: 103 kB / 0.7259 GB, free: 3.398 MB / 0.5574 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 7.534e-06/0.09581, allocations: 11.94 kB / 0.7259 GB, free: 3.387 MB / 0.5574 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 2.064e-06/0.09581, allocations: 0 / 0.7259 GB, free: 3.387 MB / 0.5574 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.003926/0.09973, allocations: 5.098 MB / 0.7309 GB, free: 13.87 MB / 0.573 GB Notification: Performance of postOpt removeConstants (simulation): time 0.0005612/0.1003, allocations: 434.4 kB / 0.7313 GB, free: 13.45 MB / 0.573 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0002596/0.1006, allocations: 116 kB / 0.7314 GB, free: 13.33 MB / 0.573 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.0006155/0.1012, allocations: 99.94 kB / 0.7315 GB, free: 13.23 MB / 0.573 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0003348/0.1015, allocations: 251.2 kB / 0.7318 GB, free: 12.99 MB / 0.573 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 0.0001095/0.1016, allocations: 95.95 kB / 0.7319 GB, free: 12.9 MB / 0.573 GB Notification: Performance of sorting global known variables: time 0.0006223/0.1022, allocations: 0.6779 MB / 0.7325 GB, free: 12.22 MB / 0.573 GB Notification: Performance of sort global known variables: time 9e-08/0.1022, allocations: 4 kB / 0.7325 GB, free: 12.21 MB / 0.573 GB Notification: Performance of remove unused functions: time 0.001114/0.1034, allocations: 0.6601 MB / 0.7332 GB, free: 11.55 MB / 0.573 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC) * Number of discrete variables: 108 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising) * Number of discrete states: 96 (patient.periodicDose.pulse.count,patient.peripheral.Cmin,$whenCondition41,patient.peripheral.Cmax,$whenCondition40,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition39,patient.periodicDose.absorptionLumen.Cmax,$whenCondition38,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition37,patient.central.Cmax,$whenCondition36,patient.central.rising,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmin,$whenCondition34,patient_high.peripheral.Cmax,$whenCondition33,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition32,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition31,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition30,patient_high.central.Cmax,$whenCondition29,patient_high.central.rising,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmin,$whenCondition27,patient_low.peripheral.Cmax,$whenCondition26,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition25,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition24,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition23,patient_low.central.Cmax,$whenCondition22,patient_low.central.rising,ref.periodicDose.pulse.count,ref.peripheral.Cmin,$whenCondition20,ref.peripheral.Cmax,$whenCondition19,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition18,ref.periodicDose.absorptionLumen.Cmax,$whenCondition17,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition16,ref.central.Cmax,$whenCondition15,ref.central.rising,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmin,$whenCondition13,ref_high.peripheral.Cmax,$whenCondition12,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition11,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition10,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition9,ref_high.central.Cmax,$whenCondition8,ref_high.central.rising,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmin,$whenCondition6,ref_low.peripheral.Cmax,$whenCondition5,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition4,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition3,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition2,ref_low.central.Cmax,$whenCondition1,ref_low.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (228): * Single equations (assignments): 198 * Array equations: 0 * Algorithm blocks: 18 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0002988/0.1036, allocations: 340.8 kB / 0.7335 GB, free: 11.22 MB / 0.573 GB Notification: Performance of simCode: created initialization part: time 0.002763/0.1064, allocations: 4.055 MB / 0.7375 GB, free: 6.605 MB / 0.573 GB Notification: Performance of simCode: created event and clocks part: time 3.086e-06/0.1064, allocations: 4 kB / 0.7375 GB, free: 6.602 MB / 0.573 GB Notification: Performance of simCode: created simulation system equations: time 0.001417/0.1078, allocations: 2.346 MB / 0.7398 GB, free: 3.918 MB / 0.573 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.00185/0.1097, allocations: 0.7083 MB / 0.7405 GB, free: 3.266 MB / 0.573 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.006459/0.1161, allocations: 5.856 MB / 0.7462 GB, free: 13.4 MB / 0.5887 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.0002894/0.1164, allocations: 389.6 kB / 0.7465 GB, free: 12.99 MB / 0.5887 GB Notification: Performance of simCode: alias equations: time 0.0006313/0.1171, allocations: 243.1 kB / 0.7468 GB, free: 12.77 MB / 0.5887 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.0003113/0.1174, allocations: 172.4 kB / 0.7469 GB, free: 12.6 MB / 0.5887 GB Notification: Performance of SimCode: time 7.81e-07/0.1174, allocations: 0 / 0.7469 GB, free: 12.6 MB / 0.5887 GB Notification: Performance of Templates: time 0.03745/0.1548, allocations: 36.03 MB / 0.7821 GB, free: 10.41 MB / 0.6199 GB " [Timeout remaining time 660] make -j1 -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.sim & ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic -abortSlowSimulation -alarm=240 -lv LOG_STATS > Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 5.899628593120724]