Environment - simulationEnvironment: startTime=0 stopTime=864000 tolerance=1e-06 numberOfIntervals=86400 stepSize=10 Regular simulation (default: the solver the model asks for, DASSL unless it says otherwise): ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment -abortSlowSimulation -alarm=240 -lv LOG_STATS LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient4.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient4.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient_citalopram_CYP2C19_2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_CYP2C19_2.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient2.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient_citalopram_normal.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_normal.dose.absorptionLumen.M, has value: -1e-10" LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0.00373563s reading init.xml | | | | | | 0.000322015s reading info.xml | | | | | | 7.7155e-05s [ 0.0%] pre-initialization | | | | | | 0.000108684s [ 0.0%] initialization | | | | | | 4.969e-06s [ 0.0%] steps | | | | | | 0.0257142s [ 5.1%] solver (excl. callbacks) | | | | | | 0s [ 0.0%] creating output-file | | | | | | 0.196139s [ 39.1%] event-handling | | | | | | 0.0105216s [ 2.1%] overhead | | | | | | 0.268891s [ 53.6%] simulation | | | | | | 0.501457s [100.0%] total | | | | | events | | | | | | 111 state events | | | | | | 0 time events | | | | | solver: dassl | | | | | | 1310 steps taken | | | | | | 1678 calls of functionODE | | | | | | 998 evaluations of jacobian | | | | | | 55 error test failures | | | | | | 0 convergence test failures | | | | | | 0.00455799s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.