Environment - simulationEnvironment: startTime=0 stopTime=86400 tolerance=1e-06 numberOfIntervals=86400 stepSize=1 Regular simulation (ida: SUNDIALS IDA): (cd run_ida && ../Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic -abortSlowSimulation -alarm=240 -lv LOG_STATS -inputPath=.. -s ida) LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((patient_high.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_high.periodicDose.absorptionLumen.M, has value: -4.73948e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((patient_low.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_low.periodicDose.absorptionLumen.M, has value: -4.73948e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((patient.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient.periodicDose.absorptionLumen.M, has value: -4.73948e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((ref_high.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= ref_high.periodicDose.absorptionLumen.M, has value: -4.73948e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((ref_low.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= ref_low.periodicDose.absorptionLumen.M, has value: -4.73948e-12" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1217.000000 | | | | ((ref.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= ref.periodicDose.absorptionLumen.M, has value: -4.73948e-12" LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0s reading init.xml | | | | | | 0s reading info.xml | | | | | | 2.4666e-05s [ 0.0%] pre-initialization | | | | | | 0.000141897s [ 0.0%] initialization | | | | | | 0s [ 0.0%] steps | | | | | | 0.027423s [ 3.1%] solver (excl. callbacks) | | | | | | 0.0177635s [ 2.0%] creating output-file | | | | | | 0.00116372s [ 0.1%] event-handling | | | | | | 0s [ 0.0%] overhead | | | | | | 0.84682s [ 94.8%] simulation | | | | | | 0.893337s [100.0%] total | | | | | events | | | | | | 81 state events | | | | | | 0 time events | | | | | solver: ida | | | | | | 1529 steps taken | | | | | | 1749 calls of functionODE | | | | | | 1053 evaluations of jacobian | | | | | | 22 error test failures | | | | | | 0 convergence test failures | | | | | | 0.0106006s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.