startTime=0 stopTime=15000 tolerance=1e-06 numberOfIntervals=2500 stepSize=6 Regular simulation: ./Physiolibrary_Physiolibrary.Chemical.Examples.Hemoglobin.Allosteric_Hemoglobin2_MWC -abortSlowSimulation -alarm=480 -lv LOG_STATS assert | warning | The following assertion has been violated at time 0.000000 | | | | solution.mass >= 0.0 and solution.mass <= 0.0 assert | warning | Variable violating min/max constraint: 0.0 <= solution.mass <= 0.0, has value: 1.00007 assert | warning | The following assertion has been violated at time 0.000000 | | | | R0_in_R.subunitSolution.nj >= 0.0 assert | warning | Variable violating min constraint: 0.0 <= R0_in_R.subunitSolution.nj, has value: -6.5552e-07 assert | warning | The following assertion has been violated at time 0.000000 | | | | R0_in_R.subunitSolution.mj >= 0.0 and R0_in_R.subunitSolution.mj <= 0.0 assert | warning | Variable violating min/max constraint: 0.0 <= R0_in_R.subunitSolution.mj <= 0.0, has value: -1.18094e-08 assert | warning | The following assertion has been violated at time 0.000000 | | | | T0_in_T.subunitSolution.nj >= 0.0 assert | warning | Variable violating min constraint: 0.0 <= T0_in_T.subunitSolution.nj, has value: -0.00399934 assert | warning | The following assertion has been violated at time 0.000000 | | | | T0_in_T.subunitSolution.mj >= 0.0 and T0_in_T.subunitSolution.mj <= 0.0 assert | warning | Variable violating min/max constraint: 0.0 <= T0_in_T.subunitSolution.mj <= 0.0, has value: -7.20493e-05 assert | warning | The following assertion has been violated at time 0.000000 | | | | DeoxyRHm[1].solution.n >= 0.0 and DeoxyRHm[1].solution.n <= 0.0 assert | warning | Variable violating min/max constraint: 0.0 <= DeoxyRHm[1].solution.n <= 0.0, has value: 1.01629 assert | warning | The following assertion has been violated at time 0.000000 | | | | H2O.SelfClustering_K >= 0.0 and H2O.SelfClustering_K <= 1.0 assert | warning | Variable violating min/max constraint: 0.0 <= H2O.SelfClustering_K <= 1.0, has value: 53.7264 LOG_SUCCESS | info | The initialization finished successfully without homotopy method. stdout | warning | The default linear solver fails, the fallback solver with total pivoting is started at time 0.000017. That might raise performance issues, for more information use -lv LOG_LS. stdout | warning | The default linear solver fails, the fallback solver with total pivoting is started at time 0.002263. That might raise performance issues, for more information use -lv LOG_LS. stdout | info | Chattering detected around time 4.03113700689e-07..0.0333039771409 (100 state events in a row with a total time delta less than the step size 3). This can be a performance bottleneck. Use -lv LOG_EVENTS for more information. The zero-crossing was: oxygenation_R[4].rr < 1e-15 assert | debug | Aborting simulation due to chattering being detected and the simulation flags requesting we do not continue further.