Environment - simulationEnvironment: startTime=0 stopTime=864000 tolerance=1e-06 numberOfIntervals=864000 stepSize=1 Regular simulation (gbode: the generic bi-rate ODE solver, with the radauIIA3 method): ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.Patient_PKPG_1C_Lithium -abortSlowSimulation -alarm=240 -lv LOG_STATS -s gbode -gbm=radauIIA3 LOG_STDOUT | warning | Numerical Jacobians without coloring are currently not supported by GBODE. Colored numerical Jacobian will be used. LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable] | | | | The following assertion has been violated at time 722.000000 | | | | ((dose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= dose.absorptionLumen.C, has value: -2.42864e-06" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 722.000000 | | | | ((dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= dose.absorptionLumen.M, has value: -2.42864e-06" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable] | | | | The following assertion has been violated at time 722.000000 | | | | ((dose.absorptionLumen.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= dose.absorptionLumen.Cmin, has value: -2.42864e-06" LOG_STATS | info | gbode (single-rate integration): radauIIA3 LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0.0012575s reading init.xml | | | | | | 0.000102443s reading info.xml | | | | | | 0.000120557s [ 0.0%] pre-initialization | | | | | | 5.2479e-05s [ 0.0%] initialization | | | | | | 2.0439e-05s [ 0.0%] steps | | | | | | 0s [ 0.0%] solver (excl. callbacks) | | | | | | 0s [ 0.0%] creating output-file | | | | | | 0.00783313s [ 0.7%] event-handling | | | | | | 0.0947191s [ 8.6%] overhead | | | | | | 0.994299s [ 90.6%] simulation | | | | | | 1.09705s [100.0%] total | | | | | events | | | | | | 61 state events | | | | | | 0 time events | | | | | solver: gbode | | | | | | 297 steps taken | | | | | | 1359 calls of functionODE | | | | | | 75 evaluations of jacobian | | | | | | 19 error test failures | | | | | | 0 convergence test failures | | | | | | 0.000105375s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.