Environment - simulationEnvironment:
startTime=0
stopTime=86400
tolerance=1e-12
numberOfIntervals=864
stepSize=100
Regular simulation (gbode: the generic bi-rate ODE solver, with the radauIIA3 method): ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic -abortSlowSimulation -alarm=240  -lv LOG_STATS -s gbode -gbm=radauIIA3
LOG_STDOUT        | warning | Numerical Jacobians without coloring are currently not supported by GBODE. Colored numerical Jacobian will be used.
LOG_SUCCESS       | info    | The initialization finished successfully without homotopy method.
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 660.000000
|                 | |       | ((patient_low.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_low.periodicDose.absorptionLumen.M, has value: -3.93163e-11"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable]
|                 | |       | The following assertion has been violated at time 660.000000
|                 | |       | ((patient_low.periodicDose.variableDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_low.periodicDose.variableDose.TotalCumulativeMass, has value: -3.95704e-11"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 660.000000
|                 | |       | ((patient_high.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_high.periodicDose.absorptionLumen.M, has value: -3.93163e-11"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable]
|                 | |       | The following assertion has been violated at time 660.000000
|                 | |       | ((patient_high.periodicDose.variableDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_high.periodicDose.variableDose.TotalCumulativeMass, has value: -3.95704e-11"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 660.000000
|                 | |       | ((patient.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient.periodicDose.absorptionLumen.M, has value: -3.93163e-11"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable]
|                 | |       | The following assertion has been violated at time 660.000000
|                 | |       | ((patient.periodicDose.variableDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient.periodicDose.variableDose.TotalCumulativeMass, has value: -3.95704e-11"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 29460.000000
|                 | |       | ((patient_low.periodicDose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= patient_low.periodicDose.absorptionLumen.C, has value: -2.21134e-07"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 29460.000000
|                 | |       | ((patient_high.periodicDose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= patient_high.periodicDose.absorptionLumen.C, has value: -2.21134e-07"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 29460.000000
|                 | |       | ((patient.periodicDose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= patient.periodicDose.absorptionLumen.C, has value: -2.21134e-07"
LOG_STATS         | info    | gbode (single-rate integration): radauIIA3
LOG_STATS         | info    | ### STATISTICS ###
|                 | |       | | timer
|                 | |       | | |   0.00599996s          reading init.xml
|                 | |       | | |  0.000587855s          reading info.xml
|                 | |       | | |  0.000137699s [  0.9%] pre-initialization
|                 | |       | | |  0.000107943s [  0.7%] initialization
|                 | |       | | |    6.773e-06s [  0.0%] steps
|                 | |       | | |            0s [  0.0%] solver (excl. callbacks)
|                 | |       | | |            0s [  0.0%] creating output-file
|                 | |       | | |  0.000465845s [  3.0%] event-handling
|                 | |       | | |   3.7249e-05s [  0.2%] overhead
|                 | |       | | |    0.0148671s [ 95.2%] simulation
|                 | |       | | |    0.0156226s [100.0%] total
|                 | |       | | events
|                 | |       | | |   113 state events
|                 | |       | | |     0 time events
|                 | |       | | solver: gbode
|                 | |       | | |  1579 steps taken
|                 | |       | | |  6634 calls of functionODE
|                 | |       | | |   119 evaluations of jacobian
|                 | |       | | |    76 error test failures
|                 | |       | | |     0 convergence test failures
|                 | |       | | | 0.000159505s time of jacobian evaluation
LOG_SUCCESS       | info    | The simulation finished successfully.