Environment - simulationEnvironment:
startTime=0
stopTime=864000
tolerance=1e-06
numberOfIntervals=86400
stepSize=10
Regular simulation (gbode: the generic bi-rate ODE solver, with the radauIIA3 method): ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment -abortSlowSimulation -alarm=240  -lv LOG_STATS -s gbode -gbm=radauIIA3
LOG_STDOUT        | warning | Numerical Jacobians without coloring are currently not supported by GBODE. Colored numerical Jacobian will be used.
LOG_SUCCESS       | info    | The initialization finished successfully without homotopy method.
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient4.dose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= patient4.dose.absorptionLumen.C, has value: -3.16025e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient4.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient4.dose.absorptionLumen.M, has value: -3.16025e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient4.dose.absorptionLumen.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= patient4.dose.absorptionLumen.Cmin, has value: -3.16025e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient_citalopram_CYP2C19_2.dose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= patient_citalopram_CYP2C19_2.dose.absorptionLumen.C, has value: -3.16025e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient_citalopram_CYP2C19_2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_CYP2C19_2.dose.absorptionLumen.M, has value: -3.16025e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= patient_citalopram_CYP2C19_2.dose.absorptionLumen.Cmin, has value: -3.16025e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient2.dose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= patient2.dose.absorptionLumen.C, has value: -3.16025e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient2.dose.absorptionLumen.M, has value: -3.16025e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient2.dose.absorptionLumen.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= patient2.dose.absorptionLumen.Cmin, has value: -3.16025e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient_citalopram_normal.dose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= patient_citalopram_normal.dose.absorptionLumen.C, has value: -3.16025e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient_citalopram_normal.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_normal.dose.absorptionLumen.M, has value: -3.16025e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable]
|                 | |       | The following assertion has been violated at time 432750.000000
|                 | |       | ((patient_citalopram_normal.dose.absorptionLumen.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= patient_citalopram_normal.dose.absorptionLumen.Cmin, has value: -3.16025e-08"
LOG_STATS         | info    | gbode (single-rate integration): radauIIA3
LOG_STATS         | info    | ### STATISTICS ###
|                 | |       | | timer
|                 | |       | | |   0.00402942s          reading init.xml
|                 | |       | | |  0.000302529s          reading info.xml
|                 | |       | | |  0.000146074s [  0.1%] pre-initialization
|                 | |       | | |   9.3496e-05s [  0.0%] initialization
|                 | |       | | |   1.6421e-05s [  0.0%] steps
|                 | |       | | |            0s [  0.0%] solver (excl. callbacks)
|                 | |       | | |            0s [  0.0%] creating output-file
|                 | |       | | |   0.00253232s [  0.9%] event-handling
|                 | |       | | |   0.00968087s [  3.5%] overhead
|                 | |       | | |     0.265866s [ 95.5%] simulation
|                 | |       | | |     0.278335s [100.0%] total
|                 | |       | | events
|                 | |       | | |    42 state events
|                 | |       | | |     0 time events
|                 | |       | | solver: gbode
|                 | |       | | |   209 steps taken
|                 | |       | | |   941 calls of functionODE
|                 | |       | | |    52 evaluations of jacobian
|                 | |       | | |    12 error test failures
|                 | |       | | |     0 convergence test failures
|                 | |       | | | 0.000189924s time of jacobian evaluation
LOG_SUCCESS       | info    | The simulation finished successfully.