Environment - simulationEnvironment:
startTime=0
stopTime=86400
tolerance=1e-06
numberOfIntervals=8640
stepSize=10
Regular simulation (gbode: the generic bi-rate ODE solver, with the radauIIA3 method): ./Pharmacolibrary_Pharmacolibrary.Examples.Paracetamol_Experiment -abortSlowSimulation -alarm=240  -lv LOG_STATS -s gbode -gbm=radauIIA3
LOG_STDOUT        | warning | Numerical Jacobians without coloring are currently not supported by GBODE. Colored numerical Jacobian will be used.
LOG_SUCCESS       | info    | The initialization finished successfully without homotopy method.
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((rapid_met.central.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= rapid_met.central.C, has value: -4.55178e-07"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((rapid_met.central.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= rapid_met.central.M, has value: -4.32419e-10"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((rapid_met.periodicDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= rapid_met.periodicDose.TotalCumulativeMass, has value: -4.32262e-10"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((rapid_met.periodicDose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= rapid_met.periodicDose.absorptionLumen.C, has value: -1.25e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((rapid_met.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= rapid_met.periodicDose.absorptionLumen.M, has value: -1.25e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((rapid_met.periodicDose.absorptionLumen.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= rapid_met.periodicDose.absorptionLumen.Cmin, has value: -1.25e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((rapid_met.periodicDose.variableDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= rapid_met.periodicDose.variableDose.TotalCumulativeMass, has value: -1.29323e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((poor_met.central.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= poor_met.central.C, has value: -4.55112e-07"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((poor_met.central.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= poor_met.central.M, has value: -4.32356e-10"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((poor_met.periodicDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= poor_met.periodicDose.TotalCumulativeMass, has value: -4.32262e-10"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((poor_met.periodicDose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= poor_met.periodicDose.absorptionLumen.C, has value: -1.25e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((poor_met.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= poor_met.periodicDose.absorptionLumen.M, has value: -1.25e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((poor_met.periodicDose.absorptionLumen.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= poor_met.periodicDose.absorptionLumen.Cmin, has value: -1.25e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((poor_met.periodicDose.variableDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= poor_met.periodicDose.variableDose.TotalCumulativeMass, has value: -1.29323e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((normal.central.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= normal.central.C, has value: -4.55145e-07"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((normal.central.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= normal.central.M, has value: -4.32387e-10"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((normal.periodicDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= normal.periodicDose.TotalCumulativeMass, has value: -4.32262e-10"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((normal.periodicDose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= normal.periodicDose.absorptionLumen.C, has value: -1.25e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((normal.periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= normal.periodicDose.absorptionLumen.M, has value: -1.25e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((normal.periodicDose.absorptionLumen.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= normal.periodicDose.absorptionLumen.Cmin, has value: -1.25e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable]
|                 | |       | The following assertion has been violated at time 646.074231
|                 | |       | ((normal.periodicDose.variableDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= normal.periodicDose.variableDose.TotalCumulativeMass, has value: -1.29323e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable]
|                 | |       | The following assertion has been violated at time 662.083039
|                 | |       | ((rapid_met.central.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= rapid_met.central.Cmin, has value: -2.01501e-06"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Pharmacokinetic/ClearanceDrivenElimination.mo:6:3-6:80:writable]
|                 | |       | The following assertion has been violated at time 662.083039
|                 | |       | ((rapid_met.elim.MExc >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= rapid_met.elim.MExc, has value: -1.42322e-12"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable]
|                 | |       | The following assertion has been violated at time 662.083039
|                 | |       | ((poor_met.central.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= poor_met.central.Cmin, has value: -2.01561e-06"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable]
|                 | |       | The following assertion has been violated at time 662.083039
|                 | |       | ((normal.central.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= normal.central.Cmin, has value: -2.01531e-06"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Pharmacokinetic/ClearanceDrivenElimination.mo:6:3-6:80:writable]
|                 | |       | The following assertion has been violated at time 662.083039
|                 | |       | ((normal.elim.MExc >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= normal.elim.MExc, has value: -1.13835e-12"
LOG_STATS         | info    | gbode (single-rate integration): radauIIA3
LOG_STATS         | info    | ### STATISTICS ###
|                 | |       | | timer
|                 | |       | | |   0.00248021s          reading init.xml
|                 | |       | | |  0.000238438s          reading info.xml
|                 | |       | | |  0.000129493s [  1.2%] pre-initialization
|                 | |       | | |   8.6413e-05s [  0.8%] initialization
|                 | |       | | |    3.477e-06s [  0.0%] steps
|                 | |       | | |            0s [  0.0%] solver (excl. callbacks)
|                 | |       | | |            0s [  0.0%] creating output-file
|                 | |       | | |  0.000225551s [  2.1%] event-handling
|                 | |       | | |  0.000384125s [  3.6%] overhead
|                 | |       | | |   0.00979993s [ 92.2%] simulation
|                 | |       | | |     0.010629s [100.0%] total
|                 | |       | | events
|                 | |       | | |    24 state events
|                 | |       | | |     0 time events
|                 | |       | | solver: gbode
|                 | |       | | |   217 steps taken
|                 | |       | | |   890 calls of functionODE
|                 | |       | | |    25 evaluations of jacobian
|                 | |       | | |    19 error test failures
|                 | |       | | |     0 convergence test failures
|                 | |       | | | 1.3025e-05s time of jacobian evaluation
LOG_SUCCESS       | info    | The simulation finished successfully.