Environment - simulationEnvironment:
startTime=0
stopTime=14400
tolerance=1e-09
numberOfIntervals=144000
stepSize=0.1
Regular simulation (gbode: the generic bi-rate ODE solver, with the radauIIA3 method): ./Pharmacolibrary_Pharmacolibrary.Drugs.N_NervousSystem.N06B_PsychostimulantsAgentsUsedForAdhdAndNootropics.N06BC01_Caffeine.Caffeine -abortSlowSimulation -alarm=240  -lv LOG_STATS -s gbode -gbm=radauIIA3
LOG_STDOUT        | warning | Numerical Jacobians without coloring are currently not supported by GBODE. Colored numerical Jacobian will be used.
LOG_SUCCESS       | info    | The initialization finished successfully without homotopy method.
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 646.056069
|                 | |       | ((periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= periodicDose.absorptionLumen.M, has value: -3.59281e-11"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable]
|                 | |       | The following assertion has been violated at time 646.056069
|                 | |       | ((periodicDose.variableDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= periodicDose.variableDose.TotalCumulativeMass, has value: -3.6773e-11"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable]
|                 | |       | The following assertion has been violated at time 647.700000
|                 | |       | ((central.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= central.M, has value: -1.0093e-12"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable]
|                 | |       | The following assertion has been violated at time 647.700000
|                 | |       | ((periodicDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= periodicDose.TotalCumulativeMass, has value: -1.0089e-12"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 651.700000
|                 | |       | ((central.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= central.C, has value: -1.33454e-09"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable]
|                 | |       | The following assertion has been violated at time 651.700000
|                 | |       | ((periodicDose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= periodicDose.absorptionLumen.C, has value: -7.91669e-09"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Pharmacokinetic/Models/PK_1C.mo:27:3-28:174:writable]
|                 | |       | The following assertion has been violated at time 651.700000
|                 | |       | ((C_central >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= C_central, has value: -1.33454e-09"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:21:3-21:56:writable]
|                 | |       | The following assertion has been violated at time 656.080151
|                 | |       | ((central.Cmin >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= central.Cmin, has value: -2.69645e-08"
LOG_ASSERT        | info    | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:20:3-20:56:writable]
|                 | |       | The following assertion has been violated at time 658.200000
|                 | |       | ((central.Cmax >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= central.Cmax, has value: -2.7149e-08"
LOG_STATS         | info    | gbode (single-rate integration): radauIIA3
LOG_STATS         | info    | ### STATISTICS ###
|                 | |       | | timer
|                 | |       | | |  0.000864154s          reading init.xml
|                 | |       | | |   9.7423e-05s          reading info.xml
|                 | |       | | |  0.000108173s [  0.1%] pre-initialization
|                 | |       | | |   3.3604e-05s [  0.0%] initialization
|                 | |       | | |   1.7323e-05s [  0.0%] steps
|                 | |       | | |            0s [  0.0%] solver (excl. callbacks)
|                 | |       | | |            0s [  0.0%] creating output-file
|                 | |       | | |   0.00101837s [  1.2%] event-handling
|                 | |       | | |   0.00492573s [  5.7%] overhead
|                 | |       | | |    0.0798965s [ 92.9%] simulation
|                 | |       | | |    0.0859997s [100.0%] total
|                 | |       | | events
|                 | |       | | |     8 state events
|                 | |       | | |     0 time events
|                 | |       | | solver: gbode
|                 | |       | | |   124 steps taken
|                 | |       | | |   468 calls of functionODE
|                 | |       | | |     9 evaluations of jacobian
|                 | |       | | |     4 error test failures
|                 | |       | | |     0 convergence test failures
|                 | |       | | | 3.925e-06s time of jacobian evaluation
LOG_SUCCESS       | info    | The simulation finished successfully.