Environment - simulationEnvironment: startTime=0 stopTime=86400 tolerance=1e-12 numberOfIntervals=86400 stepSize=1 Regular simulation (gbode: the generic bi-rate ODE solver, with the radauIIA3 method): ./Pharmacolibrary_Pharmacolibrary.Drugs.N_NervousSystem.N02B_OtherAnalgesicsAndAntipyretics.N02BE01_Paracetamol.Paracetamol_healthy_oral -abortSlowSimulation -alarm=240 -lv LOG_STATS -s gbode -gbm=radauIIA3 LOG_STDOUT | warning | Numerical Jacobians without coloring are currently not supported by GBODE. Colored numerical Jacobian will be used. LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:9:3-9:108:writable] | | | | The following assertion has been violated at time 1260.000000 | | | | ((periodicDose.absorptionLumen.C >= -1e-9)) --> "Variable violating min constraint: -1e-9 <= periodicDose.absorptionLumen.C, has value: -5.92542e-09" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 1260.000000 | | | | ((periodicDose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= periodicDose.absorptionLumen.M, has value: -5.92542e-09" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialDrugSource.mo:6:9-6:96:writable] | | | | The following assertion has been violated at time 1260.000000 | | | | ((periodicDose.variableDose.TotalCumulativeMass >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= periodicDose.variableDose.TotalCumulativeMass, has value: -5.92556e-09" LOG_STATS | info | gbode (single-rate integration): radauIIA3 LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0.000926061s reading init.xml | | | | | | 0.000105528s reading info.xml | | | | | | 0.000123002s [ 0.2%] pre-initialization | | | | | | 4.3481e-05s [ 0.1%] initialization | | | | | | 1.3576e-05s [ 0.0%] steps | | | | | | 0s [ 0.0%] solver (excl. callbacks) | | | | | | 0s [ 0.0%] creating output-file | | | | | | 0.00065041s [ 1.2%] event-handling | | | | | | 0.00315721s [ 5.8%] overhead | | | | | | 0.0503999s [ 92.7%] simulation | | | | | | 0.0543876s [100.0%] total | | | | | events | | | | | | 10 state events | | | | | | 0 time events | | | | | solver: gbode | | | | | | 506 steps taken | | | | | | 2007 calls of functionODE | | | | | | 12 evaluations of jacobian | | | | | | 23 error test failures | | | | | | 0 convergence test failures | | | | | | 4.56e-06s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.