Environment - simulationEnvironment: startTime=0 stopTime=864000 tolerance=1e-06 numberOfIntervals=864000 stepSize=1 Regular simulation (cvode: SUNDIALS CVODE): ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.Patient_PKPG_1C_Lithium -abortSlowSimulation -alarm=240 -lv LOG_STATS -s cvode LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 736.000000 | | | | ((dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= dose.absorptionLumen.M, has value: -8.42848e-12" LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0.00137562s reading init.xml | | | | | | 0.000123121s reading info.xml | | | | | | 9.0761e-05s [ 0.0%] pre-initialization | | | | | | 6.1175e-05s [ 0.0%] initialization | | | | | | 2.796e-06s [ 0.0%] steps | | | | | | 0.479895s [ 17.6%] solver (excl. callbacks) | | | | | | 0s [ 0.0%] creating output-file | | | | | | 0.00761329s [ 0.3%] event-handling | | | | | | 0.102713s [ 3.8%] overhead | | | | | | 2.13357s [ 78.3%] simulation | | | | | | 2.72394s [100.0%] total | | | | | events | | | | | | 61 state events | | | | | | 0 time events | | | | | solver: cvode | | | | | | 864292 steps taken | | | | | | 864574 calls of functionODE | | | | | | 14441 evaluations of jacobian | | | | | | 14 error test failures | | | | | | 0 convergence test failures | | | | | | 0s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.