Environment - simulationEnvironment: startTime=0 stopTime=864000 tolerance=1e-06 numberOfIntervals=86400 stepSize=10 Regular simulation (cvode: SUNDIALS CVODE): ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment -abortSlowSimulation -alarm=240 -lv LOG_STATS -s cvode LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 750.000000 | | | | ((patient4.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient4.dose.absorptionLumen.M, has value: -3.44723e-11" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 750.000000 | | | | ((patient_citalopram_CYP2C19_2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_CYP2C19_2.dose.absorptionLumen.M, has value: -3.44723e-11" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 750.000000 | | | | ((patient2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient2.dose.absorptionLumen.M, has value: -3.44723e-11" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 750.000000 | | | | ((patient_citalopram_normal.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_normal.dose.absorptionLumen.M, has value: -3.44723e-11" LOG_STATS | info | ### STATISTICS ### | | | | | timer | | | | | | 0.00373616s reading init.xml | | | | | | 0.000321996s reading info.xml | | | | | | 0.000115076s [ 0.0%] pre-initialization | | | | | | 0.000106961s [ 0.0%] initialization | | | | | | 7.053e-06s [ 0.0%] steps | | | | | | 0.0903335s [ 10.5%] solver (excl. callbacks) | | | | | | 0s [ 0.0%] creating output-file | | | | | | 0.00315158s [ 0.4%] event-handling | | | | | | 0.0142468s [ 1.7%] overhead | | | | | | 0.750746s [ 87.4%] simulation | | | | | | 0.858707s [100.0%] total | | | | | events | | | | | | 78 state events | | | | | | 0 time events | | | | | solver: cvode | | | | | | 86751 steps taken | | | | | | 87121 calls of functionODE | | | | | | 1509 evaluations of jacobian | | | | | | 29 error test failures | | | | | | 0 convergence test failures | | | | | | 0s time of jacobian evaluation LOG_SUCCESS | info | The simulation finished successfully.