Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.0009034/0.0009034, allocations: 92.2 kB / 20.19 MB, free: 4.363 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.0009535/0.0009535, allocations: 173 kB / 23.49 MB, free: 1.055 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 0.9441/0.9441, allocations: 177.1 MB / 203.8 MB, free: 5.633 MB / 186.7 MB " [Timeout remaining time 179] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 1.613/1.613, allocations: 273.5 MB / 0.5213 GB, free: 14.8 MB / 458.7 MB " [Timeout remaining time 178] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") [Timeout 660] "Notification: Performance of FrontEnd - loaded program: time 1.754e-06/1.754e-06, allocations: 0 / 0.6462 GB, free: 39.25 MB / 0.5262 GB Notification: Performance of FrontEnd - Absyn->SCode: time 1.111e-05/1.287e-05, allocations: 2.312 kB / 0.6462 GB, free: 39.25 MB / 0.5262 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic): time 0.00774/0.007753, allocations: 13.34 MB / 0.6592 GB, free: 30.5 MB / 0.5262 GB Notification: Performance of NFInst.instExpressions: time 0.003175/0.01093, allocations: 2.681 MB / 0.6619 GB, free: 28.6 MB / 0.5262 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.0004923/0.01142, allocations: 22.31 kB / 0.6619 GB, free: 28.6 MB / 0.5262 GB Notification: Performance of NFTyping.typeComponents: time 0.0003772/0.0118, allocations: 308.5 kB / 0.6622 GB, free: 28.42 MB / 0.5262 GB Notification: Performance of NFTyping.typeBindings: time 0.0009395/0.01274, allocations: 0.9079 MB / 0.6631 GB, free: 27.74 MB / 0.5262 GB Notification: Performance of NFTyping.typeClassSections: time 0.0007003/0.01344, allocations: 0.673 MB / 0.6637 GB, free: 27.29 MB / 0.5262 GB Notification: Performance of NFFlatten.flatten: time 0.001572/0.01501, allocations: 3.268 MB / 0.6669 GB, free: 25.43 MB / 0.5262 GB Notification: Performance of NFFlatten.resolveConnections: time 0.0004496/0.01546, allocations: 464.2 kB / 0.6674 GB, free: 25.16 MB / 0.5262 GB Notification: Performance of NFEvalConstants.evaluate: time 0.0009633/0.01642, allocations: 1.653 MB / 0.669 GB, free: 24.41 MB / 0.5262 GB Notification: Performance of NFSimplifyModel.simplify: time 0.0007704/0.01719, allocations: 0.9425 MB / 0.6699 GB, free: 24.08 MB / 0.5262 GB Notification: Performance of NFPackage.collectConstants: time 0.000238/0.01743, allocations: 285.5 kB / 0.6702 GB, free: 24.08 MB / 0.5262 GB Notification: Performance of NFFlatten.collectFunctions: time 0.0002639/0.01769, allocations: 290.6 kB / 0.6704 GB, free: 24.07 MB / 0.5262 GB Notification: Performance of NFScalarize.scalarize: time 0.0002002/0.0179, allocations: 0.5025 MB / 0.6709 GB, free: 23.7 MB / 0.5262 GB Notification: Performance of NFVerifyModel.verify: time 0.0006044/0.0185, allocations: 0.9567 MB / 0.6719 GB, free: 23.27 MB / 0.5262 GB Notification: Performance of NFConvertDAE.convert: time 0.001214/0.01971, allocations: 1.906 MB / 0.6737 GB, free: 22.24 MB / 0.5262 GB Notification: Performance of FrontEnd - DAE generated: time 2.354e-06/0.01972, allocations: 0 / 0.6737 GB, free: 22.24 MB / 0.5262 GB Notification: Performance of FrontEnd: time 8.51e-07/0.01972, allocations: 1.719 kB / 0.6737 GB, free: 22.24 MB / 0.5262 GB Notification: Performance of Transformations before backend: time 1.79e-05/0.01973, allocations: 0.9375 kB / 0.6737 GB, free: 22.24 MB / 0.5262 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 402 * Number of variables: 402 Notification: Performance of Generate backend data structure: time 0.002559/0.02229, allocations: 3.219 MB / 0.6769 GB, free: 19.83 MB / 0.5262 GB Notification: Performance of prepare preOptimizeDAE: time 3.488e-05/0.02233, allocations: 10.59 kB / 0.6769 GB, free: 19.83 MB / 0.5262 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.0003429/0.02267, allocations: 376.3 kB / 0.6772 GB, free: 19.66 MB / 0.5262 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.0008879/0.02356, allocations: 0.9609 MB / 0.6782 GB, free: 18.99 MB / 0.5262 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 6.013e-05/0.02362, allocations: 120.1 kB / 0.6783 GB, free: 18.95 MB / 0.5262 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.0001905/0.02381, allocations: 194.4 kB / 0.6785 GB, free: 18.88 MB / 0.5262 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.001759/0.02557, allocations: 1.809 MB / 0.6802 GB, free: 17.79 MB / 0.5262 GB Notification: Performance of preOpt findStateOrder (simulation): time 5.954e-05/0.02563, allocations: 39.94 kB / 0.6803 GB, free: 17.77 MB / 0.5262 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 9.824e-05/0.02573, allocations: 73.92 kB / 0.6803 GB, free: 17.71 MB / 0.5262 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 3.011e-05/0.02576, allocations: 36.34 kB / 0.6804 GB, free: 17.71 MB / 0.5262 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.00129/0.02705, allocations: 1.35 MB / 0.6817 GB, free: 17.02 MB / 0.5262 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.00421/0.03126, allocations: 5.129 MB / 0.6867 GB, free: 13.5 MB / 0.5262 GB Notification: Performance of preOpt comSubExp (simulation): time 0.001383/0.03264, allocations: 1.427 MB / 0.6881 GB, free: 12.56 MB / 0.5262 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.0006406/0.03328, allocations: 0.9211 MB / 0.689 GB, free: 11.79 MB / 0.5262 GB Notification: Performance of preOpt evalFunc (simulation): time 7.399e-05/0.03335, allocations: 42.27 kB / 0.689 GB, free: 11.78 MB / 0.5262 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.001348/0.0347, allocations: 2.636 MB / 0.6916 GB, free: 9.309 MB / 0.5262 GB Notification: Performance of pre-optimization done (n=264): time 3.567e-06/0.03471, allocations: 0 / 0.6916 GB, free: 9.309 MB / 0.5262 GB Notification: Performance of matching and sorting (n=282): time 0.0062/0.04091, allocations: 8.774 MB / 0.7002 GB, free: 1.355 MB / 0.5262 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.0003079/0.04121, allocations: 1.648 MB / 0.7018 GB, free: 15.33 MB / 0.5418 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.0009505/0.04216, allocations: 1.111 MB / 0.7029 GB, free: 14.19 MB / 0.5418 GB Notification: Performance of collectPreVariables (initialization): time 0.0001231/0.04229, allocations: 121.6 kB / 0.703 GB, free: 14.06 MB / 0.5418 GB Notification: Performance of collectInitialEqns (initialization): time 0.0003943/0.04268, allocations: 0.7509 MB / 0.7037 GB, free: 13.3 MB / 0.5418 GB Notification: Performance of collectInitialBindings (initialization): time 0.0005008/0.04318, allocations: 0.9145 MB / 0.7046 GB, free: 12.38 MB / 0.5418 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0004771/0.04366, allocations: 482.6 kB / 0.7051 GB, free: 11.9 MB / 0.5418 GB Notification: Performance of setup shared object (initialization): time 9.378e-05/0.04375, allocations: 484.7 kB / 0.7055 GB, free: 11.42 MB / 0.5418 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.001097/0.04485, allocations: 1.183 MB / 0.7067 GB, free: 10.08 MB / 0.5418 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.00134/0.04619, allocations: 2.228 MB / 0.7089 GB, free: 7.234 MB / 0.5418 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.00299/0.04918, allocations: 4.206 MB / 0.713 GB, free: 2.219 MB / 0.5418 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 8.977e-06/0.04919, allocations: 8 kB / 0.713 GB, free: 2.211 MB / 0.5418 GB Notification: Performance of matching and sorting (n=426) (initialization): time 0.002943/0.05213, allocations: 3.628 MB / 0.7165 GB, free: 14.27 MB / 0.5574 GB Notification: Performance of prepare postOptimizeDAE: time 0.0002112/0.05234, allocations: 0.6736 MB / 0.7172 GB, free: 13.45 MB / 0.5574 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 2.031e-05/0.05236, allocations: 27.56 kB / 0.7172 GB, free: 13.43 MB / 0.5574 GB Notification: Performance of postOpt tearingSystem (initialization): time 3.162e-05/0.0524, allocations: 36 kB / 0.7173 GB, free: 13.39 MB / 0.5574 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.001236/0.05363, allocations: 0.6592 MB / 0.7179 GB, free: 12.73 MB / 0.5574 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 3.146e-05/0.05366, allocations: 51.84 kB / 0.7179 GB, free: 12.68 MB / 0.5574 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.0006788/0.05434, allocations: 143.8 kB / 0.7181 GB, free: 12.54 MB / 0.5574 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.0001314/0.05447, allocations: 132 kB / 0.7182 GB, free: 12.41 MB / 0.5574 GB Warning: Assuming fixed start value for the following 84 variables: ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 174 ($PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (402): * Single equations (assignments): 378 * Array equations: 0 * Algorithm blocks: 24 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.001095/0.05557, allocations: 1.283 MB / 0.7195 GB, free: 11.06 MB / 0.5574 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0002965/0.05587, allocations: 338.7 kB / 0.7198 GB, free: 10.73 MB / 0.5574 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.0001886/0.05605, allocations: 208.9 kB / 0.72 GB, free: 10.52 MB / 0.5574 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 1.095e-05/0.05607, allocations: 20 kB / 0.72 GB, free: 10.5 MB / 0.5574 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 1.34e-05/0.05608, allocations: 8 kB / 0.72 GB, free: 10.49 MB / 0.5574 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 1.39e-05/0.05609, allocations: 11.95 kB / 0.72 GB, free: 10.48 MB / 0.5574 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.004531/0.06062, allocations: 5.455 MB / 0.7254 GB, free: 4.754 MB / 0.5574 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 5.49e-06/0.06063, allocations: 0 / 0.7254 GB, free: 4.754 MB / 0.5574 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.001048/0.06168, allocations: 427.4 kB / 0.7258 GB, free: 4.336 MB / 0.5574 GB Notification: Performance of postOpt tearingSystem (simulation): time 8.125e-06/0.06169, allocations: 12 kB / 0.7258 GB, free: 4.324 MB / 0.5574 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0001207/0.06181, allocations: 99.94 kB / 0.7259 GB, free: 4.227 MB / 0.5574 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 7.133e-06/0.06181, allocations: 11.19 kB / 0.7259 GB, free: 4.219 MB / 0.5574 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 1.874e-06/0.06182, allocations: 0 / 0.7259 GB, free: 4.219 MB / 0.5574 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.003839/0.06565, allocations: 5.094 MB / 0.7309 GB, free: 14.71 MB / 0.573 GB Notification: Performance of postOpt removeConstants (simulation): time 0.0005299/0.06618, allocations: 426.5 kB / 0.7313 GB, free: 14.3 MB / 0.573 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0002459/0.06643, allocations: 124 kB / 0.7314 GB, free: 14.18 MB / 0.573 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.0005962/0.06703, allocations: 95.95 kB / 0.7315 GB, free: 14.08 MB / 0.573 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0002889/0.06731, allocations: 239.2 kB / 0.7317 GB, free: 13.84 MB / 0.573 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 0.0001036/0.06742, allocations: 103.9 kB / 0.7318 GB, free: 13.74 MB / 0.573 GB Notification: Performance of sorting global known variables: time 0.0005884/0.06801, allocations: 0.6778 MB / 0.7325 GB, free: 13.06 MB / 0.573 GB Notification: Performance of sort global known variables: time 6e-08/0.06801, allocations: 0 / 0.7325 GB, free: 13.06 MB / 0.573 GB Notification: Performance of remove unused functions: time 0.001171/0.06918, allocations: 0.6523 MB / 0.7331 GB, free: 12.41 MB / 0.573 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC) * Number of discrete variables: 108 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising) * Number of discrete states: 96 (patient.periodicDose.pulse.count,patient.peripheral.Cmin,$whenCondition41,patient.peripheral.Cmax,$whenCondition40,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition39,patient.periodicDose.absorptionLumen.Cmax,$whenCondition38,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition37,patient.central.Cmax,$whenCondition36,patient.central.rising,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmin,$whenCondition34,patient_high.peripheral.Cmax,$whenCondition33,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition32,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition31,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition30,patient_high.central.Cmax,$whenCondition29,patient_high.central.rising,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmin,$whenCondition27,patient_low.peripheral.Cmax,$whenCondition26,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition25,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition24,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition23,patient_low.central.Cmax,$whenCondition22,patient_low.central.rising,ref.periodicDose.pulse.count,ref.peripheral.Cmin,$whenCondition20,ref.peripheral.Cmax,$whenCondition19,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition18,ref.periodicDose.absorptionLumen.Cmax,$whenCondition17,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition16,ref.central.Cmax,$whenCondition15,ref.central.rising,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmin,$whenCondition13,ref_high.peripheral.Cmax,$whenCondition12,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition11,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition10,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition9,ref_high.central.Cmax,$whenCondition8,ref_high.central.rising,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmin,$whenCondition6,ref_low.peripheral.Cmax,$whenCondition5,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition4,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition3,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition2,ref_low.central.Cmax,$whenCondition1,ref_low.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (228): * Single equations (assignments): 198 * Array equations: 0 * Algorithm blocks: 18 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0002838/0.06946, allocations: 340.4 kB / 0.7334 GB, free: 12.08 MB / 0.573 GB Notification: Performance of simCode: created initialization part: time 0.002586/0.07205, allocations: 4.065 MB / 0.7374 GB, free: 7.453 MB / 0.573 GB Notification: Performance of simCode: created event and clocks part: time 2.295e-06/0.07205, allocations: 0 / 0.7374 GB, free: 7.453 MB / 0.573 GB Notification: Performance of simCode: created simulation system equations: time 0.001453/0.0735, allocations: 2.336 MB / 0.7397 GB, free: 4.781 MB / 0.573 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.001784/0.07529, allocations: 0.7172 MB / 0.7404 GB, free: 4.117 MB / 0.573 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.005994/0.08128, allocations: 5.907 MB / 0.7461 GB, free: 14.2 MB / 0.5887 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.0007139/0.082, allocations: 0.8743 MB / 0.747 GB, free: 13.29 MB / 0.5887 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.000369/0.08236, allocations: 176.5 kB / 0.7472 GB, free: 13.11 MB / 0.5887 GB Notification: Performance of SimCode: time 1.012e-06/0.08237, allocations: 0 / 0.7472 GB, free: 13.11 MB / 0.5887 GB Notification: Performance of Templates: time 0.02401/0.1064, allocations: 31.69 MB / 0.7781 GB, free: 14.29 MB / 0.6199 GB " [Timeout remaining time 660] make -j1 -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.sim & ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic > Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 6.504132620058954]