Environment - simulationEnvironment: startTime=0 stopTime=864000 tolerance=1e-06 numberOfIntervals=86400 stepSize=10 Regular simulation: ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_Lithium_Experiment -abortSlowSimulation -alarm=240 -lv LOG_STATS LOG_SUCCESS | info | The initialization finished successfully without homotopy method. LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient4.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient4.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient_citalopram_CYP2C19_2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_CYP2C19_2.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient2.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient2.dose.absorptionLumen.M, has value: -1e-10" LOG_ASSERT | info | [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Interfaces/PartialCompartment.mo:18:3-18:49:writable] | | | | The following assertion has been violated at time 729.666473 | | | | ((patient_citalopram_normal.dose.absorptionLumen.M >= -1e-12)) --> "Variable violating min constraint: -1e-12 <= patient_citalopram_normal.dose.absorptionLumen.M, has value: -1e-10" LOG_SUCCESS | info | The simulation finished successfully. LOG_STATS | info | ### STATISTICS ### LOG_STATS | info | timer LOG_STATS | info | | 0s reading init.xml LOG_STATS | info | | 0s reading info.xml LOG_STATS | info | | 2.3414e-05s [ 0.0%] pre-initialization LOG_STATS | info | | 9.8595e-05s [ 0.0%] initialization LOG_STATS | info | | 0s [ 0.0%] steps LOG_STATS | info | | 0.0413283s [ 6.5%] solver (excl. callbacks) LOG_STATS | info | | 0.0741568s [ 11.6%] creating output-file LOG_STATS | info | | 0.192761s [ 30.2%] event-handling LOG_STATS | info | | 0s [ 0.0%] overhead LOG_STATS | info | | 0.330302s [ 51.7%] simulation LOG_STATS | info | | 0.63867s [100.0%] total LOG_STATS | info | events LOG_STATS | info | | 111 state events LOG_STATS | info | | 0 time events LOG_STATS | info | solver: dassl LOG_STATS | info | | 1310 steps taken LOG_STATS | info | | 1678 calls of functionODE LOG_STATS | info | | 998 evaluations of jacobian LOG_STATS | info | | 55 error test failures LOG_STATS | info | | 0 convergence test failures LOG_STATS | info | | 0.00418598s time of jacobian evaluation