Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.0009697/0.0009697, allocations: 73.88 kB / 20.65 MB, free: 3.844 MB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.001183/0.001183, allocations: 169 kB / 24.06 MB, free: 452 kB / 18.57 MB " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 0.9884/0.9884, allocations: 177.1 MB / 204.5 MB, free: 5.477 MB / 186.7 MB " [Timeout remaining time 179] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 1.587/1.587, allocations: 273.5 MB / 0.522 GB, free: 14.7 MB / 458.7 MB " [Timeout remaining time 178] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") translateModel(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic,tolerance=1e-12,outputFormat="empty",numberOfIntervals=864,variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic") [Timeout 660] "Notification: Performance of FrontEnd - loaded program: time 1.713e-06/1.713e-06, allocations: 3.562 kB / 0.6482 GB, free: 38.44 MB / 0.5262 GB Notification: Performance of FrontEnd - Absyn->SCode: time 1.625e-05/1.796e-05, allocations: 2.312 kB / 0.6482 GB, free: 38.43 MB / 0.5262 GB Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic): time 0.007542/0.00756, allocations: 13.08 MB / 0.6609 GB, free: 29.69 MB / 0.5262 GB Notification: Performance of NFInst.instExpressions: time 0.003347/0.01091, allocations: 2.668 MB / 0.6636 GB, free: 27.8 MB / 0.5262 GB Notification: Performance of NFInst.updateImplicitVariability: time 0.0005278/0.01143, allocations: 20.72 kB / 0.6636 GB, free: 27.79 MB / 0.5262 GB Notification: Performance of NFTyping.typeComponents: time 0.000357/0.01179, allocations: 307.3 kB / 0.6639 GB, free: 27.62 MB / 0.5262 GB Notification: Performance of NFTyping.typeBindings: time 0.0009865/0.01278, allocations: 0.9088 MB / 0.6648 GB, free: 26.95 MB / 0.5262 GB Notification: Performance of NFTyping.typeClassSections: time 0.0006935/0.01347, allocations: 0.6798 MB / 0.6654 GB, free: 26.49 MB / 0.5262 GB Notification: Performance of NFFlatten.flatten: time 0.001651/0.01512, allocations: 3.262 MB / 0.6686 GB, free: 24.64 MB / 0.5262 GB Notification: Performance of NFFlatten.resolveConnections: time 0.0004458/0.01557, allocations: 461.6 kB / 0.669 GB, free: 24.37 MB / 0.5262 GB Notification: Performance of NFEvalConstants.evaluate: time 0.0009871/0.01656, allocations: 1.66 MB / 0.6707 GB, free: 23.62 MB / 0.5262 GB Notification: Performance of NFSimplifyModel.simplify: time 0.0007684/0.01732, allocations: 0.9341 MB / 0.6716 GB, free: 23.3 MB / 0.5262 GB Notification: Performance of NFPackage.collectConstants: time 0.0002306/0.01755, allocations: 283.8 kB / 0.6718 GB, free: 23.3 MB / 0.5262 GB Notification: Performance of NFFlatten.collectFunctions: time 0.000282/0.01784, allocations: 284.9 kB / 0.6721 GB, free: 23.3 MB / 0.5262 GB Notification: Performance of NFScalarize.scalarize: time 0.0002064/0.01804, allocations: 0.509 MB / 0.6726 GB, free: 22.91 MB / 0.5262 GB Notification: Performance of NFVerifyModel.verify: time 0.0006253/0.01867, allocations: 0.9465 MB / 0.6735 GB, free: 22.49 MB / 0.5262 GB Notification: Performance of NFConvertDAE.convert: time 0.001125/0.01979, allocations: 1.909 MB / 0.6754 GB, free: 21.46 MB / 0.5262 GB Notification: Performance of FrontEnd - DAE generated: time 2.945e-06/0.0198, allocations: 0.9844 kB / 0.6754 GB, free: 21.46 MB / 0.5262 GB Notification: Performance of FrontEnd: time 5.82e-07/0.0198, allocations: 3.156 kB / 0.6754 GB, free: 21.46 MB / 0.5262 GB Notification: Performance of Transformations before backend: time 1.58e-05/0.01981, allocations: 0 / 0.6754 GB, free: 21.46 MB / 0.5262 GB Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 402 * Number of variables: 402 Notification: Performance of Generate backend data structure: time 0.00247/0.02228, allocations: 3.241 MB / 0.6786 GB, free: 19.04 MB / 0.5262 GB Notification: Performance of prepare preOptimizeDAE: time 2.937e-05/0.02231, allocations: 9.781 kB / 0.6786 GB, free: 19.04 MB / 0.5262 GB Notification: Performance of preOpt normalInlineFunction (simulation): time 0.0003225/0.02263, allocations: 380.2 kB / 0.6789 GB, free: 18.86 MB / 0.5262 GB Notification: Performance of preOpt evaluateParameters (simulation): time 0.0007517/0.02339, allocations: 0.9377 MB / 0.6799 GB, free: 18.2 MB / 0.5262 GB Notification: Performance of preOpt simplifyIfEquations (simulation): time 5.924e-05/0.02344, allocations: 124.2 kB / 0.68 GB, free: 18.15 MB / 0.5262 GB Notification: Performance of preOpt expandDerOperator (simulation): time 0.0001764/0.02362, allocations: 199.5 kB / 0.6802 GB, free: 18.08 MB / 0.5262 GB Notification: Performance of preOpt clockPartitioning (simulation): time 0.001341/0.02496, allocations: 1.71 MB / 0.6818 GB, free: 17.04 MB / 0.5262 GB Notification: Performance of preOpt findStateOrder (simulation): time 5.229e-05/0.02501, allocations: 35.66 kB / 0.6819 GB, free: 17.02 MB / 0.5262 GB Notification: Performance of preOpt replaceEdgeChange (simulation): time 8.778e-05/0.0251, allocations: 66.38 kB / 0.6819 GB, free: 16.97 MB / 0.5262 GB Notification: Performance of preOpt inlineArrayEqn (simulation): time 1.952e-05/0.02512, allocations: 36.19 kB / 0.682 GB, free: 16.97 MB / 0.5262 GB Notification: Performance of preOpt removeEqualRHS (simulation): time 0.0009449/0.02607, allocations: 1.247 MB / 0.6832 GB, free: 16.31 MB / 0.5262 GB Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.003846/0.02991, allocations: 4.968 MB / 0.688 GB, free: 12.86 MB / 0.5262 GB Notification: Performance of preOpt comSubExp (simulation): time 0.001039/0.03095, allocations: 1.348 MB / 0.6894 GB, free: 11.93 MB / 0.5262 GB Notification: Performance of preOpt resolveLoops (simulation): time 0.0004756/0.03143, allocations: 0.8644 MB / 0.6902 GB, free: 11.16 MB / 0.5262 GB Notification: Performance of preOpt evalFunc (simulation): time 6.927e-05/0.0315, allocations: 38.89 kB / 0.6902 GB, free: 11.16 MB / 0.5262 GB Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.001148/0.03264, allocations: 2.568 MB / 0.6927 GB, free: 8.715 MB / 0.5262 GB Notification: Performance of pre-optimization done (n=264): time 3.377e-06/0.03265, allocations: 0 / 0.6927 GB, free: 8.715 MB / 0.5262 GB Notification: Performance of matching and sorting (n=282): time 0.005028/0.03767, allocations: 7.048 MB / 0.6996 GB, free: 2.641 MB / 0.5262 GB Notification: Performance of inlineWhenForInitialization (initialization): time 0.0001908/0.03787, allocations: 1.648 MB / 0.7012 GB, free: 0.6172 MB / 0.5262 GB Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.0006877/0.03855, allocations: 1.079 MB / 0.7023 GB, free: 15.5 MB / 0.5418 GB Notification: Performance of collectPreVariables (initialization): time 0.0001275/0.03868, allocations: 117.7 kB / 0.7024 GB, free: 15.38 MB / 0.5418 GB Notification: Performance of collectInitialEqns (initialization): time 0.000418/0.0391, allocations: 0.7623 MB / 0.7031 GB, free: 14.61 MB / 0.5418 GB Notification: Performance of collectInitialBindings (initialization): time 0.0004788/0.03958, allocations: 0.9259 MB / 0.7041 GB, free: 13.68 MB / 0.5418 GB Notification: Performance of simplifyInitialFunctions (initialization): time 0.0004688/0.04005, allocations: 494.3 kB / 0.7045 GB, free: 13.18 MB / 0.5418 GB Notification: Performance of setup shared object (initialization): time 9.532e-05/0.04014, allocations: 480.7 kB / 0.705 GB, free: 12.71 MB / 0.5418 GB Notification: Performance of preBalanceInitialSystem (initialization): time 0.0007004/0.04084, allocations: 1.105 MB / 0.7061 GB, free: 11.45 MB / 0.5418 GB Notification: Performance of partitionIndependentBlocks (initialization): time 0.001151/0.04199, allocations: 2.146 MB / 0.7082 GB, free: 8.684 MB / 0.5418 GB Notification: Performance of analyzeInitialSystem (initialization): time 0.002505/0.0445, allocations: 4.01 MB / 0.7121 GB, free: 3.867 MB / 0.5418 GB Notification: Performance of solveInitialSystemEqSystem (initialization): time 1.044e-05/0.04451, allocations: 4 kB / 0.7121 GB, free: 3.863 MB / 0.5418 GB Notification: Performance of matching and sorting (n=426) (initialization): time 0.002781/0.04729, allocations: 3.429 MB / 0.7154 GB, free: 132 kB / 0.5418 GB Notification: Performance of prepare postOptimizeDAE: time 0.0002329/0.04752, allocations: 0.6727 MB / 0.7161 GB, free: 15.31 MB / 0.5574 GB Notification: Performance of postOpt simplifyComplexFunction (initialization): time 2.18e-05/0.04754, allocations: 23.98 kB / 0.7161 GB, free: 15.29 MB / 0.5574 GB Notification: Performance of postOpt tearingSystem (initialization): time 2.776e-05/0.04757, allocations: 36 kB / 0.7161 GB, free: 15.25 MB / 0.5574 GB Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.001211/0.04878, allocations: 0.6635 MB / 0.7168 GB, free: 14.59 MB / 0.5574 GB Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 2.84e-05/0.04881, allocations: 51.8 kB / 0.7168 GB, free: 14.54 MB / 0.5574 GB Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.0007032/0.04951, allocations: 135.9 kB / 0.717 GB, free: 14.4 MB / 0.5574 GB Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.0001202/0.04963, allocations: 108 kB / 0.7171 GB, free: 14.3 MB / 0.5574 GB Warning: Assuming fixed start value for the following 84 variables: ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 174 ($PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (402): * Single equations (assignments): 378 * Array equations: 0 * Algorithm blocks: 24 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.0009467/0.05058, allocations: 1.294 MB / 0.7183 GB, free: 12.93 MB / 0.5574 GB Notification: Performance of postOpt lateInlineFunction (simulation): time 0.0003047/0.05089, allocations: 334.6 kB / 0.7187 GB, free: 12.6 MB / 0.5574 GB Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.0002031/0.05109, allocations: 208.9 kB / 0.7189 GB, free: 12.39 MB / 0.5574 GB Notification: Performance of postOpt inlineArrayEqn (simulation): time 1.177e-05/0.0511, allocations: 24 kB / 0.7189 GB, free: 12.37 MB / 0.5574 GB Notification: Performance of postOpt constantLinearSystem (simulation): time 1.262e-05/0.05111, allocations: 0 / 0.7189 GB, free: 12.37 MB / 0.5574 GB Notification: Performance of postOpt simplifysemiLinear (simulation): time 1.64e-05/0.05113, allocations: 19.89 kB / 0.7189 GB, free: 12.35 MB / 0.5574 GB Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.004239/0.05537, allocations: 5.13 MB / 0.7239 GB, free: 6.961 MB / 0.5574 GB Notification: Performance of postOpt simplifyComplexFunction (simulation): time 6.703e-06/0.05538, allocations: 7.188 kB / 0.7239 GB, free: 6.957 MB / 0.5574 GB Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.001039/0.05641, allocations: 431.4 kB / 0.7243 GB, free: 6.535 MB / 0.5574 GB Notification: Performance of postOpt tearingSystem (simulation): time 8.576e-06/0.05642, allocations: 8 kB / 0.7243 GB, free: 6.527 MB / 0.5574 GB Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.0001148/0.05654, allocations: 95.94 kB / 0.7244 GB, free: 6.434 MB / 0.5574 GB Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 6.673e-06/0.05654, allocations: 8 kB / 0.7244 GB, free: 6.426 MB / 0.5574 GB Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 3.196e-06/0.05655, allocations: 4 kB / 0.7244 GB, free: 6.422 MB / 0.5574 GB Notification: Performance of postOpt symbolicJacobian (simulation): time 0.003429/0.05998, allocations: 4.863 MB / 0.7292 GB, free: 1.148 MB / 0.5574 GB Notification: Performance of postOpt removeConstants (simulation): time 0.0005252/0.0605, allocations: 434.3 kB / 0.7296 GB, free: 0.7227 MB / 0.5574 GB Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.0002605/0.06076, allocations: 120 kB / 0.7297 GB, free: 0.6055 MB / 0.5574 GB Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.0005955/0.06136, allocations: 95.95 kB / 0.7298 GB, free: 0.5117 MB / 0.5574 GB Notification: Performance of postOpt findZeroCrossings (simulation): time 0.0002942/0.06165, allocations: 255.3 kB / 0.73 GB, free: 268 kB / 0.5574 GB Notification: Performance of postOpt collapseArrayExpressions (simulation): time 9.786e-05/0.06175, allocations: 95.88 kB / 0.7301 GB, free: 172 kB / 0.5574 GB Notification: Performance of sorting global known variables: time 0.000427/0.06218, allocations: 0.6113 MB / 0.7307 GB, free: 15.55 MB / 0.573 GB Notification: Performance of sort global known variables: time 6e-08/0.06218, allocations: 0 / 0.7307 GB, free: 15.55 MB / 0.573 GB Notification: Performance of remove unused functions: time 0.001087/0.06326, allocations: 0.6523 MB / 0.7314 GB, free: 14.9 MB / 0.573 GB Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC) * Number of discrete variables: 108 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising) * Number of discrete states: 96 (patient.periodicDose.pulse.count,patient.peripheral.Cmin,$whenCondition41,patient.peripheral.Cmax,$whenCondition40,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition39,patient.periodicDose.absorptionLumen.Cmax,$whenCondition38,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition37,patient.central.Cmax,$whenCondition36,patient.central.rising,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmin,$whenCondition34,patient_high.peripheral.Cmax,$whenCondition33,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition32,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition31,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition30,patient_high.central.Cmax,$whenCondition29,patient_high.central.rising,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmin,$whenCondition27,patient_low.peripheral.Cmax,$whenCondition26,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition25,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition24,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition23,patient_low.central.Cmax,$whenCondition22,patient_low.central.rising,ref.periodicDose.pulse.count,ref.peripheral.Cmin,$whenCondition20,ref.peripheral.Cmax,$whenCondition19,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition18,ref.periodicDose.absorptionLumen.Cmax,$whenCondition17,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition16,ref.central.Cmax,$whenCondition15,ref.central.rising,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmin,$whenCondition13,ref_high.peripheral.Cmax,$whenCondition12,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition11,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition10,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition9,ref_high.central.Cmax,$whenCondition8,ref_high.central.rising,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmin,$whenCondition6,ref_low.peripheral.Cmax,$whenCondition5,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition4,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition3,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition2,ref_low.central.Cmax,$whenCondition1,ref_low.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (228): * Single equations (assignments): 198 * Array equations: 0 * Algorithm blocks: 18 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.0003008/0.06356, allocations: 345 kB / 0.7317 GB, free: 14.56 MB / 0.573 GB Notification: Performance of simCode: created initialization part: time 0.002424/0.06599, allocations: 3.884 MB / 0.7355 GB, free: 10.12 MB / 0.573 GB Notification: Performance of simCode: created event and clocks part: time 1.743e-06/0.06599, allocations: 0 / 0.7355 GB, free: 10.12 MB / 0.573 GB Notification: Performance of simCode: created simulation system equations: time 0.001162/0.06715, allocations: 2.262 MB / 0.7377 GB, free: 7.516 MB / 0.573 GB Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.001832/0.06898, allocations: 0.7128 MB / 0.7384 GB, free: 6.859 MB / 0.573 GB Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.005982/0.07497, allocations: 5.792 MB / 0.7441 GB, free: 1.062 MB / 0.573 GB Notification: Performance of simCode: some other stuff during SimCode phase: time 0.000277/0.07524, allocations: 397.5 kB / 0.7444 GB, free: 0.6445 MB / 0.573 GB Notification: Performance of simCode: alias equations: time 0.0006273/0.07587, allocations: 239.2 kB / 0.7447 GB, free: 432 kB / 0.573 GB Notification: Performance of simCode: all other stuff during SimCode phase: time 0.001265/0.07714, allocations: 0.8883 MB / 0.7455 GB, free: 15.53 MB / 0.5887 GB Notification: Performance of SimCode: time 1.042e-06/0.07714, allocations: 0 / 0.7455 GB, free: 15.53 MB / 0.5887 GB Notification: Performance of Templates: time 0.04252/0.1197, allocations: 40.43 MB / 0.785 GB, free: 8.965 MB / 0.6199 GB " [Timeout remaining time 660] make -j1 -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.makefile [Timeout 660] (rm -f Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; mkfifo Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe ; head -c 1048576 < Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe >> ../files/Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.sim & ./Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic -abortSlowSimulation -alarm=240 -lv LOG_STATS > Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PK_2C_generic.pipe 2>&1) [Timeout 240] [Calling sys.exit(0), Time elapsed: 5.747617729008198]