Running: ./testmodel.py --libraries=/home/hudson/saved_omc/libraries/.openmodelica/libraries --ompython_omhome=/usr Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic.conf.json loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "[:1:22-1:33:writable] Warning: Modelica only supports 32-bit signed integers! Transforming: 13743895347 into a real [:1:1-1:33:writable] Error: Class GC_set_max_heap_size not found in scope (looking for a function or record). Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo): time 0.0004543/0.0004543, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo): time 0.0004113/0.0004113, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo", uses=false) [Timeout 180] "Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo): time 0.3352/0.3352, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 180] loadFile("/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo", uses=false) [Timeout 180] "[/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Drugs/ATC/B/B02BD15.mo:9:22-9:32:writable] Warning: Modelica only supports 32-bit signed integers! Transforming: 6000000000 into a real [/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/Examples/package.order:0:0-0:0:readonly] Warning: The package.order file does not list all .mo files and directories (containing package.mo) present in its directory. Missing names are: Paracetamol_Experiment Notification: Performance of loadFile(/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo): time 0.8044/0.8044, allocations: 0 / 0, free: 0 / 0 " [Timeout remaining time 179] Using package Pharmacolibrary with version 25.09 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Pharmacolibrary 25.9.0/package.mo) Using package Modelica with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Modelica 4.1.0+maint.om/package.mo) Using package Complex with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/Complex 4.1.0+maint.om/package.mo) Using package ModelicaServices with version 4.1.0 (/home/hudson/saved_omc/libraries/.openmodelica/libraries/ModelicaServices 4.1.0+maint.om/package.mo) Running command: "" <> buildModelFMU(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic,fileNamePrefix="Pharmacolibrary_Pharmacolibrary_Examples_Pharmacogenomics_PKPG_2C_generic",fmuType="me_cs",version="3.0",platforms={"wasm"}) "" <> buildModelFMU(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic,fileNamePrefix="Pharmacolibrary_Pharmacolibrary_Examples_Pharmacogenomics_PKPG_2C_generic",fmuType="me_cs",version="3.0",platforms={"wasm"}) [Timeout 660] "Notification: Performance of FrontEnd - loaded program: time 3.386e-06/3.386e-06, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FrontEnd - Absyn->SCode: time 1.777e-05/2.116e-05, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFInst.instantiate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic): time 0.02959/0.02961, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFInst.instExpressions: time 0.0119/0.04151, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFInst.updateImplicitVariability: time 0.002621/0.04413, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFTyping.typeComponents: time 0.003335/0.04747, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFTyping.typeBindings: time 0.005928/0.0534, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFTyping.typeClassSections: time 0.003785/0.05718, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFFlatten.flatten: time 0.005965/0.06315, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFFlatten.resolveConnections: time 0.002516/0.06566, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFEvalConstants.evaluate: time 0.005424/0.07109, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFSimplifyModel.simplify: time 0.003704/0.07479, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFPackage.collectConstants: time 0.0007692/0.07556, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFFlatten.collectFunctions: time 0.001323/0.07688, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFScalarize.scalarize: time 0.001262/0.07815, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFVerifyModel.verify: time 0.003172/0.08132, allocations: 0 / 0, free: 0 / 0 Notification: Performance of NFConvertDAE.convert: time 0.009972/0.09129, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FrontEnd - DAE generated: time 0.0005852/0.09187, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FrontEnd: time 6.202e-06/0.09188, allocations: 0 / 0, free: 0 / 0 Notification: Performance of Transformations before backend: time 5.103e-05/0.09193, allocations: 0 / 0, free: 0 / 0 Notification: Model statistics after passing the front-end and creating the data structures used by the back-end: * Number of equations: 486 * Number of variables: 486 Notification: Performance of Generate backend data structure: time 0.01959/0.1115, allocations: 0 / 0, free: 0 / 0 Notification: Performance of prepare preOptimizeDAE: time 0.0002087/0.1117, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt introduceOutputAliases (simulation): time 0.002312/0.114, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt normalInlineFunction (simulation): time 0.008242/0.1223, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt evaluateParameters (simulation): time 0.009328/0.1316, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt simplifyIfEquations (simulation): time 0.0003652/0.132, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt expandDerOperator (simulation): time 0.001306/0.1333, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt clockPartitioning (simulation): time 0.01757/0.1508, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt findStateOrder (simulation): time 0.0003165/0.1512, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt replaceEdgeChange (simulation): time 0.0008638/0.152, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt inlineArrayEqn (simulation): time 0.0001001/0.1521, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt removeEqualRHS (simulation): time 0.0152/0.1673, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt removeSimpleEquations (simulation): time 0.03629/0.2036, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt comSubExp (simulation): time 0.01303/0.2167, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt resolveLoops (simulation): time 0.008308/0.225, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt evalFunc (simulation): time 0.0001551/0.2251, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preOpt encapsulateWhenConditions (simulation): time 0.01292/0.238, allocations: 0 / 0, free: 0 / 0 Notification: Performance of pre-optimization done (n=300): time 0.0002232/0.2383, allocations: 0 / 0, free: 0 / 0 Notification: Performance of matching and sorting (n=318): time 0.08523/0.3235, allocations: 0 / 0, free: 0 / 0 Notification: Performance of inlineWhenForInitialization (initialization): time 0.001806/0.3253, allocations: 0 / 0, free: 0 / 0 Notification: Performance of selectInitializationVariablesDAE (initialization): time 0.009986/0.3353, allocations: 0 / 0, free: 0 / 0 Notification: Performance of collectPreVariables (initialization): time 0.001579/0.3369, allocations: 0 / 0, free: 0 / 0 Notification: Performance of collectInitialEqns (initialization): time 0.002605/0.3395, allocations: 0 / 0, free: 0 / 0 Notification: Performance of collectInitialBindings (initialization): time 0.002239/0.3417, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simplifyInitialFunctions (initialization): time 0.003864/0.3456, allocations: 0 / 0, free: 0 / 0 Notification: Performance of setup shared object (initialization): time 0.0002013/0.3458, allocations: 0 / 0, free: 0 / 0 Notification: Performance of preBalanceInitialSystem (initialization): time 0.01002/0.3558, allocations: 0 / 0, free: 0 / 0 Notification: Performance of partitionIndependentBlocks (initialization): time 0.01133/0.3671, allocations: 0 / 0, free: 0 / 0 Notification: Performance of analyzeInitialSystem (initialization): time 0.04142/0.4085, allocations: 0 / 0, free: 0 / 0 Notification: Performance of solveInitialSystemEqSystem (initialization): time 8.378e-05/0.4086, allocations: 0 / 0, free: 0 / 0 Notification: Performance of matching and sorting (n=462) (initialization): time 0.03371/0.4423, allocations: 0 / 0, free: 0 / 0 Notification: Performance of prepare postOptimizeDAE: time 0.001108/0.4435, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyComplexFunction (initialization): time 9.387e-05/0.4435, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt tearingSystem (initialization): time 0.0001453/0.4437, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt solveSimpleEquations (initialization): time 0.005833/0.4495, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt calculateStrongComponentJacobians (initialization): time 0.0001588/0.4497, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyAllExpressions (initialization): time 0.004045/0.4537, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt collapseArrayExpressions (initialization): time 0.001698/0.4554, allocations: 0 / 0, free: 0 / 0 Warning: Assuming fixed start value for the following 84 variables: patient_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real patient.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real patient.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_high.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_high.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref_low.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref_low.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.central.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.periodicDose.absorptionLumen.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.periodicDose.variableDose.TotalCumulativeMass:VARIABLE(min = -1e-12 unit = \"kg\" fixed = true ) \"Total dose adminitrated by this source\" type: Real ref.peripheral.AUC:VARIABLE(unit = \"kg.s/m3\" fixed = true ) \"area under curve\" type: Real ref.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_low.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.peripheral.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.periodicDose.absorptionLumen.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmin:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real patient_high.central.Cmax:DISCRETE(min = -1e-9 unit = \"kg/m3\" fixed = true ) type: Real ref.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean ref_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_low.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.peripheral.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.periodicDose.absorptionLumen.rising:DISCRETE(fixed = true protected = true ) type: Boolean patient_high.central.rising:DISCRETE(fixed = true protected = true ) type: Boolean Notification: Model statistics after passing the back-end for initialization: * Number of independent subsystems: 96 * Number of states: 0 () * Number of discrete variables: 186 ($PRE.ref.peripheral.Cmin,ref.peripheral.Cmin,$PRE.ref.peripheral.Cmax,ref.peripheral.Cmax,$PRE.ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.Cmin,$PRE.ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmax,$PRE.ref.central.Cmin,ref.central.Cmin,$PRE.ref.central.Cmax,ref.central.Cmax,$PRE.ref_low.peripheral.Cmin,ref_low.peripheral.Cmin,$PRE.ref_low.peripheral.Cmax,ref_low.peripheral.Cmax,$PRE.ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.Cmin,$PRE.ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmax,$PRE.ref_low.central.Cmin,ref_low.central.Cmin,$PRE.ref_low.central.Cmax,ref_low.central.Cmax,$PRE.ref_high.peripheral.Cmin,ref_high.peripheral.Cmin,$PRE.ref_high.peripheral.Cmax,ref_high.peripheral.Cmax,$PRE.ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.Cmin,$PRE.ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmax,$PRE.ref_high.central.Cmin,ref_high.central.Cmin,$PRE.ref_high.central.Cmax,ref_high.central.Cmax,$PRE.patient.peripheral.Cmin,patient.peripheral.Cmin,$PRE.patient.peripheral.Cmax,patient.peripheral.Cmax,$PRE.patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.Cmin,$PRE.patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmax,$PRE.patient.central.Cmin,patient.central.Cmin,$PRE.patient.central.Cmax,patient.central.Cmax,$PRE.patient_low.peripheral.Cmin,patient_low.peripheral.Cmin,$PRE.patient_low.peripheral.Cmax,patient_low.peripheral.Cmax,$PRE.patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.Cmin,$PRE.patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmax,$PRE.patient_low.central.Cmin,patient_low.central.Cmin,$PRE.patient_low.central.Cmax,patient_low.central.Cmax,$PRE.patient_high.peripheral.Cmin,patient_high.peripheral.Cmin,$PRE.patient_high.peripheral.Cmax,patient_high.peripheral.Cmax,$PRE.patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.Cmin,$PRE.patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmax,$PRE.patient_high.central.Cmin,patient_high.central.Cmin,$PRE.patient_high.central.Cmax,patient_high.central.Cmax,$PRE.ref.peripheral.rising,$PRE.ref.periodicDose.pulse.count,$PRE.ref.periodicDose.pulse.T_start,$PRE.ref.periodicDose.absorptionLumen.rising,$PRE.ref.central.rising,ref.CYP2C19.status,ref.SLC22A2.status,ref.peripheral.rising,ref.periodicDose.pulse.count,ref.periodicDose.pulse.T_start,ref.periodicDose.absorptionLumen.rising,ref.central.rising,$whenCondition41,$whenCondition40,$whenCondition39,$whenCondition38,$whenCondition37,$whenCondition36,$whenCondition42,$PRE.ref_low.peripheral.rising,$PRE.ref_low.periodicDose.pulse.count,$PRE.ref_low.periodicDose.pulse.T_start,$PRE.ref_low.periodicDose.absorptionLumen.rising,$PRE.ref_low.central.rising,ref_low.CYP2C19.status,ref_low.SLC22A2.status,ref_low.peripheral.rising,ref_low.periodicDose.pulse.count,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.rising,$whenCondition34,$whenCondition33,$whenCondition32,$whenCondition31,$whenCondition30,$whenCondition29,$whenCondition35,$PRE.ref_high.peripheral.rising,$PRE.ref_high.periodicDose.pulse.count,$PRE.ref_high.periodicDose.pulse.T_start,$PRE.ref_high.periodicDose.absorptionLumen.rising,$PRE.ref_high.central.rising,ref_high.CYP2C19.status,ref_high.SLC22A2.status,ref_high.peripheral.rising,ref_high.periodicDose.pulse.count,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.rising,$whenCondition27,$whenCondition26,$whenCondition25,$whenCondition24,$whenCondition23,$whenCondition22,$whenCondition28,$PRE.patient.peripheral.rising,$PRE.patient.periodicDose.pulse.count,$PRE.patient.periodicDose.pulse.T_start,$PRE.patient.periodicDose.absorptionLumen.rising,$PRE.patient.central.rising,patient.CYP2C19.status,patient.SLC22A2.status,patient.peripheral.rising,patient.periodicDose.pulse.count,patient.periodicDose.pulse.T_start,patient.periodicDose.absorptionLumen.rising,patient.central.rising,$whenCondition20,$whenCondition19,$whenCondition18,$whenCondition17,$whenCondition16,$whenCondition15,$whenCondition21,$PRE.patient_low.peripheral.rising,$PRE.patient_low.periodicDose.pulse.count,$PRE.patient_low.periodicDose.pulse.T_start,$PRE.patient_low.periodicDose.absorptionLumen.rising,$PRE.patient_low.central.rising,patient_low.CYP2C19.status,patient_low.SLC22A2.status,patient_low.peripheral.rising,patient_low.periodicDose.pulse.count,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.rising,$whenCondition13,$whenCondition12,$whenCondition11,$whenCondition10,$whenCondition9,$whenCondition8,$whenCondition14,$PRE.patient_high.peripheral.rising,$PRE.patient_high.periodicDose.pulse.count,$PRE.patient_high.periodicDose.pulse.T_start,$PRE.patient_high.periodicDose.absorptionLumen.rising,$PRE.patient_high.central.rising,patient_high.CYP2C19.status,patient_high.SLC22A2.status,patient_high.peripheral.rising,patient_high.periodicDose.pulse.count,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.rising,$whenCondition6,$whenCondition5,$whenCondition4,$whenCondition3,$whenCondition2,$whenCondition1,$whenCondition7) * Number of discrete states: 0 () * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for initialization (426): * Single equations (assignments): 390 * Array equations: 0 * Algorithm blocks: 36 * Record equations: 0 * When equations: 0 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of prepare postOptimizeDAE: time 0.007769/0.4632, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt lateInlineFunction (simulation): time 0.005433/0.4686, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt wrapFunctionCalls (simulation): time 0.002058/0.4707, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt inlineArrayEqn (simulation): time 6.021e-05/0.4707, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt constantLinearSystem (simulation): time 5.448e-05/0.4708, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifysemiLinear (simulation): time 6.255e-05/0.4709, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt removeSimpleEquations (simulation): time 0.04678/0.5176, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyComplexFunction (simulation): time 3.506e-05/0.5177, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt solveSimpleEquations (simulation): time 0.004863/0.5225, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt tearingSystem (simulation): time 5.114e-05/0.5226, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt inputDerivativesUsed (simulation): time 0.001261/0.5239, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt calculateStrongComponentJacobians (simulation): time 5.759e-05/0.5239, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt calculateStateSetsJacobians (simulation): time 8.125e-06/0.5239, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt symbolicJacobian (simulation): time 0.04275/0.5667, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt removeConstants (simulation): time 0.007592/0.5743, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyTimeIndepFuncCalls (simulation): time 0.002378/0.5766, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt simplifyAllExpressions (simulation): time 0.003404/0.58, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt findZeroCrossings (simulation): time 0.004267/0.5843, allocations: 0 / 0, free: 0 / 0 Notification: Performance of postOpt collapseArrayExpressions (simulation): time 0.00152/0.5858, allocations: 0 / 0, free: 0 / 0 Notification: Performance of sorting global known variables: time 0.00661/0.5924, allocations: 0 / 0, free: 0 / 0 Notification: Performance of sort global known variables: time 0.0001083/0.5925, allocations: 0 / 0, free: 0 / 0 Notification: Performance of remove unused functions: time 0.008273/0.6008, allocations: 0 / 0, free: 0 / 0 Notification: Model statistics after passing the back-end for simulation: * Number of independent subsystems: 6 * Number of states: 54 (patient_high.central.C,patient_high.central.AUC,patient_high.elim.MExc,patient_high.periodicDose.TotalCumulativeMass,patient_high.periodicDose.absorptionLumen.C,patient_high.periodicDose.absorptionLumen.AUC,patient_high.periodicDose.variableDose.TotalCumulativeMass,patient_high.peripheral.C,patient_high.peripheral.AUC,patient_low.central.C,patient_low.central.AUC,patient_low.elim.MExc,patient_low.periodicDose.TotalCumulativeMass,patient_low.periodicDose.absorptionLumen.C,patient_low.periodicDose.absorptionLumen.AUC,patient_low.periodicDose.variableDose.TotalCumulativeMass,patient_low.peripheral.C,patient_low.peripheral.AUC,patient.central.C,patient.central.AUC,patient.elim.MExc,patient.periodicDose.TotalCumulativeMass,patient.periodicDose.absorptionLumen.C,patient.periodicDose.absorptionLumen.AUC,patient.periodicDose.variableDose.TotalCumulativeMass,patient.peripheral.C,patient.peripheral.AUC,ref_high.central.C,ref_high.central.AUC,ref_high.elim.MExc,ref_high.periodicDose.TotalCumulativeMass,ref_high.periodicDose.absorptionLumen.C,ref_high.periodicDose.absorptionLumen.AUC,ref_high.periodicDose.variableDose.TotalCumulativeMass,ref_high.peripheral.C,ref_high.peripheral.AUC,ref_low.central.C,ref_low.central.AUC,ref_low.elim.MExc,ref_low.periodicDose.TotalCumulativeMass,ref_low.periodicDose.absorptionLumen.C,ref_low.periodicDose.absorptionLumen.AUC,ref_low.periodicDose.variableDose.TotalCumulativeMass,ref_low.peripheral.C,ref_low.peripheral.AUC,ref.central.C,ref.central.AUC,ref.elim.MExc,ref.periodicDose.TotalCumulativeMass,ref.periodicDose.absorptionLumen.C,ref.periodicDose.absorptionLumen.AUC,ref.periodicDose.variableDose.TotalCumulativeMass,ref.peripheral.C,ref.peripheral.AUC) * Number of discrete variables: 120 ($whenCondition7,$whenCondition1,$whenCondition2,$whenCondition3,$whenCondition4,$whenCondition5,$whenCondition6,patient_high.central.Cmax,patient_high.central.Cmin,patient_high.central.rising,patient_high.periodicDose.absorptionLumen.Cmax,patient_high.periodicDose.absorptionLumen.Cmin,patient_high.periodicDose.absorptionLumen.rising,patient_high.periodicDose.pulse.T_start,patient_high.periodicDose.pulse.count,patient_high.peripheral.Cmax,patient_high.peripheral.Cmin,patient_high.peripheral.rising,patient_high.SLC22A2.status,patient_high.CYP2C19.status,$whenCondition14,$whenCondition8,$whenCondition9,$whenCondition10,$whenCondition11,$whenCondition12,$whenCondition13,patient_low.central.Cmax,patient_low.central.Cmin,patient_low.central.rising,patient_low.periodicDose.absorptionLumen.Cmax,patient_low.periodicDose.absorptionLumen.Cmin,patient_low.periodicDose.absorptionLumen.rising,patient_low.periodicDose.pulse.T_start,patient_low.periodicDose.pulse.count,patient_low.peripheral.Cmax,patient_low.peripheral.Cmin,patient_low.peripheral.rising,patient_low.SLC22A2.status,patient_low.CYP2C19.status,$whenCondition21,$whenCondition15,$whenCondition16,$whenCondition17,$whenCondition18,$whenCondition19,$whenCondition20,patient.central.Cmax,patient.central.Cmin,patient.central.rising,patient.periodicDose.absorptionLumen.Cmax,patient.periodicDose.absorptionLumen.Cmin,patient.periodicDose.absorptionLumen.rising,patient.periodicDose.pulse.T_start,patient.periodicDose.pulse.count,patient.peripheral.Cmax,patient.peripheral.Cmin,patient.peripheral.rising,patient.SLC22A2.status,patient.CYP2C19.status,$whenCondition28,$whenCondition22,$whenCondition23,$whenCondition24,$whenCondition25,$whenCondition26,$whenCondition27,ref_high.central.Cmax,ref_high.central.Cmin,ref_high.central.rising,ref_high.periodicDose.absorptionLumen.Cmax,ref_high.periodicDose.absorptionLumen.Cmin,ref_high.periodicDose.absorptionLumen.rising,ref_high.periodicDose.pulse.T_start,ref_high.periodicDose.pulse.count,ref_high.peripheral.Cmax,ref_high.peripheral.Cmin,ref_high.peripheral.rising,ref_high.SLC22A2.status,ref_high.CYP2C19.status,$whenCondition35,$whenCondition29,$whenCondition30,$whenCondition31,$whenCondition32,$whenCondition33,$whenCondition34,ref_low.central.Cmax,ref_low.central.Cmin,ref_low.central.rising,ref_low.periodicDose.absorptionLumen.Cmax,ref_low.periodicDose.absorptionLumen.Cmin,ref_low.periodicDose.absorptionLumen.rising,ref_low.periodicDose.pulse.T_start,ref_low.periodicDose.pulse.count,ref_low.peripheral.Cmax,ref_low.peripheral.Cmin,ref_low.peripheral.rising,ref_low.SLC22A2.status,ref_low.CYP2C19.status,$whenCondition42,$whenCondition36,$whenCondition37,$whenCondition38,$whenCondition39,$whenCondition40,$whenCondition41,ref.central.Cmax,ref.central.Cmin,ref.central.rising,ref.periodicDose.absorptionLumen.Cmax,ref.periodicDose.absorptionLumen.Cmin,ref.periodicDose.absorptionLumen.rising,ref.periodicDose.pulse.T_start,ref.periodicDose.pulse.count,ref.peripheral.Cmax,ref.peripheral.Cmin,ref.peripheral.rising,ref.SLC22A2.status,ref.CYP2C19.status) * Number of discrete states: 108 (ref.periodicDose.pulse.count,ref.CYP2C19.status,ref.SLC22A2.status,ref.peripheral.Cmin,$whenCondition41,ref.peripheral.Cmax,$whenCondition40,ref.peripheral.rising,ref.periodicDose.absorptionLumen.Cmin,$whenCondition39,ref.periodicDose.absorptionLumen.Cmax,$whenCondition38,ref.periodicDose.absorptionLumen.rising,ref.central.Cmin,$whenCondition37,ref.central.Cmax,$whenCondition36,ref.central.rising,ref_low.periodicDose.pulse.count,ref_low.CYP2C19.status,ref_low.SLC22A2.status,ref_low.peripheral.Cmin,$whenCondition34,ref_low.peripheral.Cmax,$whenCondition33,ref_low.peripheral.rising,ref_low.periodicDose.absorptionLumen.Cmin,$whenCondition32,ref_low.periodicDose.absorptionLumen.Cmax,$whenCondition31,ref_low.periodicDose.absorptionLumen.rising,ref_low.central.Cmin,$whenCondition30,ref_low.central.Cmax,$whenCondition29,ref_low.central.rising,ref_high.periodicDose.pulse.count,ref_high.CYP2C19.status,ref_high.SLC22A2.status,ref_high.peripheral.Cmin,$whenCondition27,ref_high.peripheral.Cmax,$whenCondition26,ref_high.peripheral.rising,ref_high.periodicDose.absorptionLumen.Cmin,$whenCondition25,ref_high.periodicDose.absorptionLumen.Cmax,$whenCondition24,ref_high.periodicDose.absorptionLumen.rising,ref_high.central.Cmin,$whenCondition23,ref_high.central.Cmax,$whenCondition22,ref_high.central.rising,patient.periodicDose.pulse.count,patient.CYP2C19.status,patient.SLC22A2.status,patient.peripheral.Cmin,$whenCondition20,patient.peripheral.Cmax,$whenCondition19,patient.peripheral.rising,patient.periodicDose.absorptionLumen.Cmin,$whenCondition18,patient.periodicDose.absorptionLumen.Cmax,$whenCondition17,patient.periodicDose.absorptionLumen.rising,patient.central.Cmin,$whenCondition16,patient.central.Cmax,$whenCondition15,patient.central.rising,patient_low.periodicDose.pulse.count,patient_low.CYP2C19.status,patient_low.SLC22A2.status,patient_low.peripheral.Cmin,$whenCondition13,patient_low.peripheral.Cmax,$whenCondition12,patient_low.peripheral.rising,patient_low.periodicDose.absorptionLumen.Cmin,$whenCondition11,patient_low.periodicDose.absorptionLumen.Cmax,$whenCondition10,patient_low.periodicDose.absorptionLumen.rising,patient_low.central.Cmin,$whenCondition9,patient_low.central.Cmax,$whenCondition8,patient_low.central.rising,patient_high.periodicDose.pulse.count,patient_high.CYP2C19.status,patient_high.SLC22A2.status,patient_high.peripheral.Cmin,$whenCondition6,patient_high.peripheral.Cmax,$whenCondition5,patient_high.peripheral.rising,patient_high.periodicDose.absorptionLumen.Cmin,$whenCondition4,patient_high.periodicDose.absorptionLumen.Cmax,$whenCondition3,patient_high.periodicDose.absorptionLumen.rising,patient_high.central.Cmin,$whenCondition2,patient_high.central.Cmax,$whenCondition1,patient_high.central.rising) * Number of clocked states: 0 () * Top-level inputs: 0 Notification: Strong component statistics for simulation (252): * Single equations (assignments): 210 * Array equations: 0 * Algorithm blocks: 30 * Record equations: 0 * When equations: 12 * If-equations: 0 * Equation systems (not torn): 0 * Torn equation systems: 0 * Mixed (continuous/discrete) equation systems: 0 Notification: Performance of Backend phase and start with SimCode phase: time 0.04652/0.6473, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created initialization part: time 0.02487/0.6722, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created event and clocks part: time 9.368e-06/0.6722, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created simulation system equations: time 0.01364/0.6859, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created of all other equations (e.g. parameter, nominal, assert, etc): time 0.01499/0.7008, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: created linear, non-linear and system jacobian parts: time 0.1644/0.8652, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: some other stuff during SimCode phase: time 0.005583/0.8708, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: alias equations: time 0.003242/0.8741, allocations: 0 / 0, free: 0 / 0 Notification: Performance of simCode: all other stuff during SimCode phase: time 0.008238/0.8823, allocations: 0 / 0, free: 0 / 0 Notification: Performance of SimCode: time 0.001674/0.884, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FMU modelDescription.xml: time 0.04416/0.9281, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FMU model kernel: time 0.0195/0.9476, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FMU translated model: time 0.1033/1.051, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FMU component link: time 1.682e-05/1.051, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FMU precompile: time 2.281e-05/1.051, allocations: 0 / 0, free: 0 / 0 Notification: Performance of FMU write (0.6 MB unzipped): time 0.0003227/1.051, allocations: 0 / 0, free: 0 / 0 Notification: Building FMU for platform 'wasm' (1/1). Notification: Finished FMU for platform 'wasm' (1/1). " [Timeout remaining time 659] simulate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic,startTime=0,stopTime=86400,tolerance=1e-06,numberOfIntervals=86400,outputFormat="empty",variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic",simflags=" -alarm=240 -lv LOG_STATS -startTime=0 -stopTime=86400 -tolerance=1e-06 -stepSize=1 -noemit",resimulateExecutable="Pharmacolibrary_Pharmacolibrary_Examples_Pharmacogenomics_PKPG_2C_generic.fmu") [Timeout 240] "" [Timeout remaining time 234] simulate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic,startTime=0,stopTime=86400,tolerance=1e-06,numberOfIntervals=86400,outputFormat="empty",variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic",simflags=" -alarm=240 -lv LOG_STATS -startTime=0 -stopTime=86400 -tolerance=1e-06 -stepSize=1 -noemit -s fmi3:me:daskr",resimulateExecutable="Pharmacolibrary_Pharmacolibrary_Examples_Pharmacogenomics_PKPG_2C_generic.fmu") [Timeout 240] "" [Timeout remaining time 234] simulate(Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic,startTime=0,stopTime=86400,tolerance=1e-06,numberOfIntervals=86400,outputFormat="empty",variableFilter="",fileNamePrefix="Pharmacolibrary_Pharmacolibrary.Examples.Pharmacogenomics.PKPG_2C_generic",simflags=" -alarm=240 -lv LOG_STATS -startTime=0 -stopTime=86400 -tolerance=1e-06 -stepSize=1 -noemit -s fmi3:cs",resimulateExecutable="Pharmacolibrary_Pharmacolibrary_Examples_Pharmacogenomics_PKPG_2C_generic.fmu") [Timeout 240] "" [Timeout remaining time 225] [Calling sys.exit(0), Time elapsed: 30.41103566705715]