Environment - simulationEnvironment:
startTime=0
stopTime=1.3
tolerance=1e-06
numberOfIntervals=2500
stepSize=0.00052
Regular simulation: ./Physiolibrary_Physiolibrary.Chemical.Examples.Hemoglobin.Develop.Hemoglobin_titration  -abortSlowSimulation -alarm=480 -lv LOG_STATS
LOG_SUCCESS       | info    | The initialization finished successfully without homotopy method.
assert            | warning | The following assertion has been violated at time 0.001300
|                 | |       | deoxyhemoglobin.R.carboxylation[3].products[1].conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.R.carboxylation[3].products[1].conc, has value: -1.61559e-24
assert            | warning | The following assertion has been violated at time 0.001300
|                 | |       | deoxyhemoglobin.R.NHCOO[3].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.R.NHCOO[3].state, has value: -1.61559e-27
assert            | warning | The following assertion has been violated at time 0.004680
|                 | |       | deoxyhemoglobin.R.OxyHm[1].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.R.OxyHm[1].state, has value: -1.61559e-27
assert            | warning | The following assertion has been violated at time 0.004680
|                 | |       | deoxyhemoglobin.R.OxyHm[1].q_out.conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.R.OxyHm[1].q_out.conc, has value: -1.61559e-24
assert            | warning | The following assertion has been violated at time 0.004680
|                 | |       | deoxyhemoglobin.R.OxyHm[2].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.R.OxyHm[2].state, has value: -1.61559e-27
assert            | warning | The following assertion has been violated at time 0.004680
|                 | |       | deoxyhemoglobin.R.OxyHm[2].q_out.conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.R.OxyHm[2].q_out.conc, has value: -1.61559e-24
assert            | warning | The following assertion has been violated at time 0.004680
|                 | |       | deoxyhemoglobin.R.OxyHm[3].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.R.OxyHm[3].state, has value: -1.61559e-27
assert            | warning | The following assertion has been violated at time 0.004680
|                 | |       | deoxyhemoglobin.R.OxyHm[3].q_out.conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.R.OxyHm[3].q_out.conc, has value: -1.61559e-24
assert            | warning | The following assertion has been violated at time 0.004680
|                 | |       | deoxyhemoglobin.R.OxyHm[4].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.R.OxyHm[4].state, has value: -1.61559e-27
assert            | warning | The following assertion has been violated at time 0.004680
|                 | |       | deoxyhemoglobin.R.OxyHm[4].q_out.conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.R.OxyHm[4].q_out.conc, has value: -1.61559e-24
assert            | warning | The following assertion has been violated at time 0.004680
|                 | |       | deoxyhemoglobin.R.oxygenation >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.R.oxygenation, has value: -6.46235e-27
assert            | warning | The following assertion has been violated at time 0.006760
|                 | |       | deoxyhemoglobin.T.carboxylation[3].products[1].conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.carboxylation[3].products[1].conc, has value: -2.1684e-16
assert            | warning | The following assertion has been violated at time 0.006760
|                 | |       | deoxyhemoglobin.T.carboxylation[4].products[1].conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.carboxylation[4].products[1].conc, has value: -2.1684e-16
assert            | warning | The following assertion has been violated at time 0.006760
|                 | |       | deoxyhemoglobin.T.NHCOO[3].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.NHCOO[3].state, has value: -2.1684e-19
assert            | warning | The following assertion has been violated at time 0.006760
|                 | |       | deoxyhemoglobin.T.NHCOO[4].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.NHCOO[4].state, has value: -2.1684e-19
assert            | warning | The following assertion has been violated at time 0.013780
|                 | |       | deoxyhemoglobin.T.OxyHm[1].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.OxyHm[1].state, has value: -2.1684e-19
assert            | warning | The following assertion has been violated at time 0.013780
|                 | |       | deoxyhemoglobin.T.OxyHm[1].q_out.conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.OxyHm[1].q_out.conc, has value: -2.1684e-16
assert            | warning | The following assertion has been violated at time 0.013780
|                 | |       | deoxyhemoglobin.T.OxyHm[2].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.OxyHm[2].state, has value: -2.1684e-19
assert            | warning | The following assertion has been violated at time 0.013780
|                 | |       | deoxyhemoglobin.T.OxyHm[2].q_out.conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.OxyHm[2].q_out.conc, has value: -2.1684e-16
assert            | warning | The following assertion has been violated at time 0.013780
|                 | |       | deoxyhemoglobin.T.OxyHm[3].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.OxyHm[3].state, has value: -2.1684e-19
assert            | warning | The following assertion has been violated at time 0.013780
|                 | |       | deoxyhemoglobin.T.OxyHm[3].q_out.conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.OxyHm[3].q_out.conc, has value: -2.1684e-16
assert            | warning | The following assertion has been violated at time 0.013780
|                 | |       | deoxyhemoglobin.T.OxyHm[4].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.OxyHm[4].state, has value: -2.1684e-19
assert            | warning | The following assertion has been violated at time 0.013780
|                 | |       | deoxyhemoglobin.T.OxyHm[4].q_out.conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.OxyHm[4].q_out.conc, has value: -2.1684e-16
assert            | warning | The following assertion has been violated at time 0.013780
|                 | |       | deoxyhemoglobin.T.oxygenation >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.oxygenation, has value: -8.67362e-19
assert            | warning | The following assertion has been violated at time 0.015080
|                 | |       | deoxyhemoglobin.T.carboxylation[1].products[1].conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.carboxylation[1].products[1].conc, has value: -2.1684e-16
assert            | warning | The following assertion has been violated at time 0.015080
|                 | |       | deoxyhemoglobin.T.carboxylation[2].products[1].conc >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.carboxylation[2].products[1].conc, has value: -2.1684e-16
assert            | warning | The following assertion has been violated at time 0.015080
|                 | |       | deoxyhemoglobin.T.NHCOO[1].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.NHCOO[1].state, has value: -2.1684e-19
assert            | warning | The following assertion has been violated at time 0.015080
|                 | |       | deoxyhemoglobin.T.NHCOO[2].state >= 0.0
assert            | warning | Variable violating min constraint: 0.0 <= deoxyhemoglobin.T.NHCOO[2].state, has value: -2.1684e-19
LOG_STATS         | info    | ### STATISTICS ###
|                 | |       | | timer
|                 | |       | | |    0.0286409s          reading init.xml
|                 | |       | | |   0.00374207s          reading info.xml
|                 | |       | | |  0.000184967s [  0.0%] pre-initialization
|                 | |       | | |  0.000851367s [  0.1%] initialization
|                 | |       | | |  0.000252343s [  0.0%] steps
|                 | |       | | |   0.00350271s [  0.3%] solver (excl. callbacks)
|                 | |       | | |            0s [  0.0%] creating output-file
|                 | |       | | |     0.609311s [ 47.8%] event-handling
|                 | |       | | |    0.0028053s [  0.2%] overhead
|                 | |       | | |     0.657618s [ 51.6%] simulation
|                 | |       | | |      1.27453s [100.0%] total
|                 | |       | | events
|                 | |       | | |     0 state events
|                 | |       | | |     0 time events
|                 | |       | | solver: dassl
|                 | |       | | |    23 steps taken
|                 | |       | | |    23 calls of functionODE
|                 | |       | | |    22 evaluations of jacobian
|                 | |       | | |     0 error test failures
|                 | |       | | |     0 convergence test failures
|                 | |       | | | 1.6492e-05s time of jacobian evaluation
LOG_SUCCESS       | info    | The simulation finished successfully.